Inflammatory Disease News and Research

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Ultra-sensitive C. difficile toxin assay may be critical tool for improving diagnosis of infectious disease

Findings presented at the American Society for Microbiology's ASM Microbe conference show that the ultra-sensitive Clostridium difficile toxin A/B assay in development for use on the Sgx Clarity™ system offers excellent sensitivity and may be a critical tool for improving the diagnosis of this life-threatening infection.

29 Jul 2017

Study provides fresh insights into how the body detects early signs of cancer

Fresh insights into how cells detect damage to their DNA - a hallmark of cancer - could help explain how the body keeps disease in check.

26 Jul 2017

New PET-CT scan can diagnose cardiac sarcoidosis more accurately than traditional tests

Using a new imaging technique that can diagnose cardiac sarcoidosis much more accurately than traditional tests, researchers from the University of Illinois at Chicago have found that the disease affects other organs in 40 percent of patients with cardiac sarcoidosis.

21 Jul 2017

UAB improves dry eye treatment with development of new guidelines and expansion of clinic

Clinical practice and research of dry eye relief in the University of Alabama at Birmingham School of Optometry is progressing with the development and release of new guidelines for diagnosis and treatment of dry eye, as well as the expansion of services offered by the UAB Dry Eye Relief Clinic.

11 Jul 2017

Rise in antibiotic-resistant gonorrhea, WHO report reveals

Reports from WHO, based on the data collected from 77 countries, reveals that antibiotic resistance of gonorrhea, a common sexually transmitted infection is making the disease much harder and at times impossible to treat.

7 Jul 2017

Entasis and GARDP partner to develop oral antibiotic for treatment of drug-resistant gonorrhea

Zoliflodacin, a novel first-in-class oral antibiotic and one of the only treatments in development to address the rapidly-growing threat of drug-resistant gonorrhea will enter pivotal trials, thanks to a new partnership between the not-for-profit Global Antibiotic Research and Development Partnership and Entasis Therapeutics.

7 Jul 2017

Study examines novel surgical procedure to combat peri-implantitis

Peri-implantitis is an irreversible inflammatory disease that is commonly caused by plaque and biofilm that accumulates on the exterior of a dental implant. It effects both the soft and hard tissues surrounding the implant, and without treatment, may result in excessive bone loss proximal to the implant and its eventual failure.

5 Jul 2017

Four-food elimination diet can resolve symptoms of eosinophilic esophagitis in children

Children with eosinophilic esophagitis (EoE) – a chronic inflammatory disease that injures the esophagus – who temporarily eliminated cow's milk, wheat, egg and soy from their diet for eight weeks had their symptoms and esophageal swelling resolve, according to a study published in Clinical Gastroenterology and Hepatology.

27 Jun 2017

Researchers identify new therapy target for gonorrhea

Researchers have identified a possible new treatment for gonorrhea, using a peptide that thwarts the infection-causing bacterium by interfering with an enzyme the microbe needs to respirate.

27 Jun 2017

Type I interferons could have role in natural improvement of RA during pregnancy

An international US-Danish team of scientists, led by Damini Jawaheer, Ph.D. at the UCSF Benioff Children's Hospital Oakland Research Institute, has identified a possible link between type I interferons and a natural improvement of rheumatoid arthritis (RA) during pregnancy.

21 Jun 2017

Targeting regulatory T cells could be effective approach to treating cancers, research shows

Researchers at University of Pittsburgh School of Medicine and UPMC have discovered a clue that could unlock the potential of immunotherapy drugs to successfully treat more cancers.

15 Jun 2017

Irreversible infertility risk in men linked to urogenital infections

In couples who have not been able to have children, male infertility is the cause in at least half of cases. In 6-10% the cause is a urogenital infection.

14 Jun 2017

Study emphasizes importance of molecule in maintaining balanced immune system in the gut

A healthy gut requires a molecule called gp96 to train the immune system to tolerate food and normal microbes, report researchers at the Medical University of South Carolina in the May 19, 2017 issue of Scientific Reports.

14 Jun 2017

New biosensor technology could be used in wearable devices to monitor health

Imagine wearing a device that continuously analyzes your sweat or blood for different types of biomarkers, such as proteins that show you may have breast cancer or lung cancer.

13 Jun 2017

Expedited partner therapy for STIs provides health and cost benefits

In some states, patients who test positive for chlamydia or gonorrhea leave the clinic with not only a prescription for themselves, but also one for their sexual partner -- who was not seen by a doctor.

2 Jun 2017

Glucose may play crucial role in the fight against cancer and inflammatory disease

Glucose - commonly referred to as a 'simple' sugar - may actually be crucial in the fight against cancer and inflammatory disease as scientists have just discovered a new role in which it stimulates cells that work on the frontline in the fight against tumors and infection.

30 May 2017

Trans-fatty acids promote cell death in a more direct manner than previously thought

Tohoku University researchers have found that trans-fatty acids promote cell death in a more direct manner than previously thought, leading to the development of atherosclerosis, a major cause of heart attacks and strokes.

18 May 2017

Research findings provide insight into mechanisms underlying differences in efficacy of anti-TNF drugs

Osaka University-led researchers identified differences in how three drugs bind to tumor necrosis factor, a key mediator of inflammatory disease. The team used sedimentation velocity analytical ultracentrifugation to investigate drug-target binding in a physiological environment and at clinically-relevant concentrations.

15 May 2017

Study: Systemic therapy preserves vision of uveitis patients better than intraocular implant

Systemic therapy consisting of corticosteroids and immunosuppressants preserved vision of uveitis patients better - and had fewer adverse outcomes - than a long-lasting corticosteroid intraocular implant, according to a clinical trial funded by the National Eye Institute.

9 May 2017

Scientists create new technique for studying how chlamydia interacts with immune system

Scientists at the Wellcome Trust Sanger Institute and their collaborators at the University of British Columbia have created an innovative technique for studying how chlamydia interacts with the human immune system.

25 Apr 2017