Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Fibrinogen-like protein 1 plays dual role in liver regeneration and hepatocellular carcinoma recurrence

Hepatocellular carcinoma (HCC), a leading cause of cancer-related mortality globally, exhibits a dismal five-year survival rate of only 18%.

2 Jul 2024

No organ is an island: Genetic study shows unique but interconnected aging markers

Researchers analyzed genetic underpinnings of biological age gaps in nine organ systems using a large dataset from the U.K. Biobank, revealing organ-specific yet interconnected genetic architectures. Their findings may aid in understanding complex diseases and developing holistic treatments.

2 Jul 2024

KRISS develops world's first reference material for accurate body fat measurement in medical imaging

The Korea Research Institute of Standards and Science (KRISS) has developed the world's first reference material to improve the accuracy of body fat measurements conducted through MRI and CT scans.

1 Jul 2024

New study reveals ketogenic diet's role in combating obesity

Researchers showed that ketogenic diet (KD)-induced bile acids (BAs) are protective against obesity.

1 Jul 2024

Duke researchers discover drug to restore aged livers

While the liver is one of the body's most resilient organs, it is still vulnerable to the ravages of stress and aging, leading to disease, severe scarring and failure.

26 Jun 2024

Semaglutide reduces heart risks in overweight and obese individuals without diabetes

The SELECT trial found that semaglutide significantly reduces cardiovascular events in individuals with overweight or obesity and preexisting cardiovascular disease, regardless of baseline HbA1c or changes in HbA1c levels.

26 Jun 2024

Pentraxin 3 as a predictor of advanced fibrosis and carotid intima-media thickness in MAFLD patients

Metabolic-associated fatty liver disease (MAFLD) may increase the risk of cardiovascular events. In this study, we assessed the predictive value of pentraxin 3 (PTX3) for severe fibrosis and carotid intima-media thickness (CIMT) in patients with MAFLD.

25 Jun 2024

UT Health San Antonio researcher wins NIH grant to investigate alcohol-associated liver disease

Liver transplants associated with alcohol-related disease are growing at a rapid pace, shifting research to address pathologies behind the ailments in light of a limited supply of organ donors.

21 Jun 2024

Challenges in treatment of cholangiocarcinoma in patients with primary sclerosing cholangitis

Primary sclerosing cholangitis (PSC) is a rare progressive liver disease that damages bile ducts and significantly increases the risk of bile duct cancer, particularly a type called cholangiocarcinoma (CCA).

20 Jun 2024

Study reveals genetic associations between coffee and harmful health outcomes such as obesity and substance use

Scientists have found consistent positive genetic correlations of coffee intake with substance use and obesity in US and UK adults of European ancestry.

20 Jun 2024

Study reveals overactive PKA protein as driver of fibrolamellar carcinoma

It's been enormously difficult to pinpoint the cause of many cancers - and many seem to have more than one origin. Fibrolamellar carcinoma (FLC), however, is one that scientists thought they had nailed down.

18 Jun 2024

Safety-focused summary of GLP-1 receptor agonists in diabetes, obesity, and beyond

A recent review in Diabetes Care evaluates the efficacy and safety of GLP-1 receptor agonists for type 2 diabetes and obesity, exploring their potential for new medical indications.

18 Jun 2024

Empowering communities: Penn Medicine's annual mammogram event and health fair

Penn Medicine will once again join with community partners and Siemens Healthineers to host a free mammogram clinic and community health fair in June, giving the West Philadelphia and Upper Darby communities convenient access to health screenings right in their neighborhoods.

13 Jun 2024

Innovative therapeutic strategies for combating type 2 diabetes

One of the most confusing aspects for patients with type 2 diabetes mellitus is that they have high fasting glucose levels.

7 Jun 2024

Bile acids: Balancing digestive health and liver toxicity

Bile acids are essential molecules the liver produces that play a critical role in digestion. They help us absorb fat-soluble vitamins and cholesterol from our food.

6 Jun 2024

Injectable fish oil emulsion reduces brain damage in newborn rodents

An injectable emulsion containing two omega-3 fatty acids found in fish oil markedly reduced brain damage in newborn rodents after a disruption in the flow of oxygen to the brain near birth, a study by researchers at Columbia University Vagelos College of Physicians and Surgeons has found.

6 Jun 2024

Sedentary childhood linked to premature liver damage, study finds

An increase in sedentary time from childhood caused premature liver damage, a new study shows. However, light physical activity could reverse the risk.

6 Jun 2024

Proteomic fitness scores revolutionize disease prediction and personalized exercise plans

Research establishes a proteomic CRF score, linking it to improved prediction of mortality and multisystem disease risks, showing dynamic response to exercise training.

5 Jun 2024

5-Cog paradigm: A breakthrough in dementia diagnosis and care

The underdiagnosis of dementia, especially among Black and Hispanic patients, is a long-standing challenge in medicine.

4 Jun 2024

Vasomotor symptoms in menopausal women linked to greater risk for non-alcoholic fatty liver disease

Women experiencing moderate-to-severe vasomotor symptoms face a three times greater risk for metabolic-dysfunction-associated steatotic liver disease (MASLD) compared to those with mild symptom severity, according to research being presented Monday at ENDO 2024, the Endocrine Society's annual meeting in Boston, Mass.

3 Jun 2024

Liver Disease News and Research

Further Reading

Fibrinogen-like protein 1 plays dual role in liver regeneration and hepatocellular carcinoma recurrence

No organ is an island: Genetic study shows unique but interconnected aging markers

KRISS develops world's first reference material for accurate body fat measurement in medical imaging

New study reveals ketogenic diet's role in combating obesity

Duke researchers discover drug to restore aged livers

Semaglutide reduces heart risks in overweight and obese individuals without diabetes

Pentraxin 3 as a predictor of advanced fibrosis and carotid intima-media thickness in MAFLD patients

UT Health San Antonio researcher wins NIH grant to investigate alcohol-associated liver disease

Challenges in treatment of cholangiocarcinoma in patients with primary sclerosing cholangitis

Study reveals genetic associations between coffee and harmful health outcomes such as obesity and substance use

Study reveals overactive PKA protein as driver of fibrolamellar carcinoma

Safety-focused summary of GLP-1 receptor agonists in diabetes, obesity, and beyond

Empowering communities: Penn Medicine's annual mammogram event and health fair

Innovative therapeutic strategies for combating type 2 diabetes

Bile acids: Balancing digestive health and liver toxicity

Injectable fish oil emulsion reduces brain damage in newborn rodents

Sedentary childhood linked to premature liver damage, study finds

Proteomic fitness scores revolutionize disease prediction and personalized exercise plans

5-Cog paradigm: A breakthrough in dementia diagnosis and care

Vasomotor symptoms in menopausal women linked to greater risk for non-alcoholic fatty liver disease

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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