Proteome News and Research

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The proteome is the entire complement of proteins expressed by a genome, cell, tissue or organism. More specifically, it is the expressed proteins at a given time point under defined conditions. The term is a blend of proteins and genome.

DNA synbodies, a new class of affinity reagents, gets major NIH boost

An ongoing Arizona State University effort to develop a revolutionary class of reagents that holds great promise for the future of medicine has received a major boost with a three-year, $4 million award from the National Institutes of Health.

24 Oct 2011

Older women destined to develop AD have high blood levels of pregnancy protein

In an advance toward a much-needed early diagnostic test for Alzheimer's disease (AD), scientists have discovered that older women destined to develop AD have high blood levels of a protein linked to pregnancy years before showing symptoms.

29 Sep 2011

OBT, Seattle Genetics form strategic collaboration to discover novel ADCs for cancer

Seattle Genetics, Inc. and Oxford BioTherapeutics today announced that they have formed a strategic collaboration to jointly discover novel antibody-drug conjugates (ADCs) for cancer.

14 Sep 2011

ProteinSimple introduces automated Western Blot

ProteinSimple today introduced a revolutionary new system for protein analysis, Simon and the Simple Western. The Simple Western is a complete reinvention of the Western Blot, and is truly a historic breakthrough for protein research.

From ProteinSimple 30 Aug 2011

Hutchinson Center to participate in NCI-funded proteome research consortium

The National Cancer Institute today announced that a team co-led by Fred Hutchinson Cancer Research Center and The Broad Institute in Cambridge, Mass., has been selected to participate in a National Cancer Institute-funded research consortium dedicated to understanding the molecular basis of cancer.

23 Aug 2011

New proteomics-based approach to analyze bone quality

A new technique developed at Rensselaer Polytechnic Institute allows researchers to collect large amounts of biochemical information from nanoscale bone samples.

23 Jun 2011

Scientists discover linchpin protein that drives mitochondria's calcium machinery

Mitochondria, those battery-pack organelles that fuel the energy of almost every living cell, have an insatiable appetite for calcium. Whether in a dish or a living organism, the mitochondria of most organisms eagerly absorb this chemical compound.

20 Jun 2011

New approach for identifying 'self' proteins targeted in autoimmune diseases

Researchers from Harvard Medical School and MIT have developed a new approach for identifying the "self" proteins targeted in autoimmune diseases such as multiple sclerosis, diabetes and rheumatoid arthritis.

3 Jun 2011

Bruker to showcase record performance achievements of maXis 4G system at ASMS 2011

Bruker, the pioneer of ultrahigh-resolution quadrupole time-of-flight mass spectrometry, today announced a major extension of the successful maXis UHR Qq-TOF technology range, which Bruker will showcase at the ASMS 2011 conference in Denver, Colorado, starting this Sunday, June 5.

3 Jun 2011

A new gene expression analysis technique on a single molecule sequencer

A new gene expression technique adapted for single molecule sequencing has enabled researchers at the RIKEN Omics Science Center (OSC) to accurately and quantitatively measure gene expression levels using only 100 nanograms of total RNA. The technique, which pairs RIKEN's Cap Analysis of Gene Expression (CAGE) protocol with the Helicos(R) Genetic Analysis System developed by Helicos BioSciences Corporation, opens the door to the detailed analysis of gene expression networks and rare cell populations. In recent years, next-generation DNA sequencers have produced an increasingly detailed picture of how genes are expressed at the molecular level. The transcriptional output of these genes - the RNA copies produced from DNA - has revealed a richness of complexity in transcript structure and function, providing insights into the molecular-level properties of cancers and other diseases.

19 May 2011

caprotec bioanalytics closes Series B financing for EUR 5 million

caprotec bioanalytics GmbH, a privately held biopharmaceutical company offering the proprietary Capture Compound Mass Spectrometry platform technology for the analysis of small molecule – protein interactions, today announced a second closing of EUR 1 million to its Series B financing, increasing total equity for the round to EUR 5 million.

9 May 2011

New screening marker can detect pancreatic cancer

Researchers at the University of Michigan Comprehensive Cancer Center have identified a protein that shows distinct changes in structure between pancreatic cancer, non-cancerous diseases and normal blood serum. The protein also changes from early stage pancreatic cancer to advanced disease.

28 Apr 2011

BIOBASE introduces new genome sequence custom annotation tool

BIOBASE announced its launch of a new custom annotation tool designed to aid in functional annotation of next generation sequences from uncharacterized genomes.

26 Apr 2011

New report reveals toad brains may contain germ-fighting proteins

Frog and toad skins already are renowned as cornucopias of hundreds of germ-fighting substances. Now a new report in ACS's Journal of Proteome Research reveals that the toad brains also may contain an abundance of antibacterial and antiviral substances that could inspire a new generation of medicines.

15 Apr 2011

BioWa, OBT enter license agreement to advance ADCC programs

BioWa, Inc. and Oxford BioTherapeutics Ltd today announced that they have entered into a license agreement to provide OBT with access to BioWa's patented POTELLIGENT Technology platform for the development of antibody-dependent cellular cytotoxicity enhanced antibodies.

6 Apr 2011

LIFE Biosystems to present MASE data at AACR annual meeting

Adverse events, or side effects, have traditionally been viewed as an unavoidable consequence in the therapeutic treatment of cancer patients. Yet sufficient data exists to study the relationship between molecular mechanisms, and drug-induced phenotypes to learn about - and even predict - adverse events in patients.

1 Apr 2011

Researchers characterize novel form of ubiquitin regulatory protein

Researchers at the Proteome Center Tuebingen characterize a novel form of the regulatory protein ubiquitin, involved in inflammation and cell death.

31 Mar 2011

Biognosys brings proteomic breakthroughs to mainstream users

Biognosys, a leading provider of targeted proteomics solutions, announces the software platform mProphet for large-scale applications in industrial and academic research. The software was recently published in «Nature Methods»: With the new tool researchers can analyze complex proteomics data and generate statistically validated results.

From Biognosys 25 Mar 2011

Protein serum amyloid A could be a potential diagnostic biomarker for lung cancer

Scientists are reporting discovery of a protein in the blood of lung cancer patients that could be used in a test for the disease - difficult to diagnose in its earliest and most treatable stages - and to develop drugs that stop lung cancer from spreading. Their study appears in ACS's Journal of Proteome Research.

3 Mar 2011

EPO grants three core patents to caprotec's CCMS technology

caprotec bioanalytics GmbH announced today that the European Patent Office has granted the last of three core patents protecting its proprietary and revolutionary Capture Compound Mass Spectrometry technology.

28 Feb 2011