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Entirely new approach to the treatment of aging

Dispelling the belief that the only way to treat such conditions is by fixing or replacing damaged genes, they instead focused on the field of epigenetics—the study of changes in gene silencing that occur without changes in the genes themselves.

3 Aug 2004

Third of heart failure patients face increased risk of death because they do not receive an angiotensin-converting enzyme (ACE) inhibitor

Overwhelming evidence accumulated during almost 20 years of clinical experience has established the benefits of this drug, which blocks the harmful effects of angiotensin, a substance that causes blood vessels to narrow, said the study authors.

3 Aug 2004

CV Therapeutics initiates approval-enabling trial of drug to treat chronic angina

CV Therapeutics has announced that it has initiated an approval-enabling study of Ranexa, which, if successful, could support approval of Ranexa for the treatment of chronic angina in a restricted patient population.

3 Aug 2004

New Drug Application with the U.S. Food and Drug Administration for Tarceva

OSI Pharmaceuticals and Genentech have announced that OSI completed the submission of a New Drug Application with the U.S. Food and Drug Administration for Tarceva (erlotinib HCl),

3 Aug 2004

Recommendation against the use of chemotherapy sensitivity and resistance assays

A new technology assessment from the American Society of Clinical Oncology states that the use of chemotherapy sensitivity and resistance assays (CSRAs) to select chemotherapeutic agents for cancer patients should not be undertaken outside of the clinical trial setting.

3 Aug 2004

Adhering to established guidelines improves survival and reduces the risk of breast cancer

The first study to compare survival between women with breast cancer whose treatment was based on consensus guidelines and those whose treatment was not shows that adhering to established guidelines improves survival and reduces the risk of recurrence.

3 Aug 2004

Home test kit for common sexually transmitted diseases

Researchers at Johns Hopkins have launched the first government-sponsored study to measure the effectiveness of a Web- and community-based home test kit for common sexually transmitted diseases, such as Chlamydia and gonorrhea.

3 Aug 2004

One-third of U.S. adults use some form of alternative medicine

More than one-third of U.S. adults use some form of alternative medicine such as herbal supplements and other therapies, showed in a nationwide survey by NIH's National Center for Complementary and Alternative Medicine published in May 2004.

2 Aug 2004

Smart gene therapy might effectively prevent the organ damage commonly suffered by heart attack victims

Early intervention with a novel kind of "smart gene therapy" might effectively prevent the organ damage commonly suffered by heart attack victims, suggests a new animal study by researchers at Brigham and Women's Hospital in Boston and Duke University Medical Center.

2 Aug 2004

Mining giant Rio Tinto has developed and implemented a global HIV/AIDS strategy

Rio Tinto’s response to HIV/AIDS draws upon the International Labour Organisation (ILO) Code of Good Practice on HIV/AIDS. Discrimination towards employees on the basis of real or perceived HIV status is not tolerated. The confidentiality of all information on the HIV status and condition of employees and community members is strictly upheld.

2 Aug 2004

Inexpensive generic three-in-one fixed-dose combination pill taken twice a day has helped HIV/AIDS patients in Uganda

The Arua Hospital AIDS Program today commemorated two years of providing free access to antiretroviral (ARV) treatment for nearly 1,100 people living with HIV/AIDS in Arua, a rural region in northwestern Uganda.

2 Aug 2004

New approach to cancer vaccines may eradicate skin cancer tumors

Mayo Clinic and British researchers have developed a new approach to cancer vaccines that purposely kills healthy skin cells to target the immune system against tumors. The new approach has eradicated skin cancer tumors in mice.

2 Aug 2004

Clinical benefit for moderate-to-severe plaque psoriasis patients treated with Raptiva for 30 months

Genentech and XOMA have announced preliminary 30-month (120 weeks) results from an open-label study evaluating the safety and efficacy of long-term continuous treatment with RAPTIVA® (efalizumab) in adults with moderate-to-severe chronic plaque psoriasis.

2 Aug 2004

Negative side effects of iron for people with kidney disease

More than 20 million Americans– one in nine adults– have chronic kidney disease, and most don't even know it.

2 Aug 2004

A more direct lateral approach to minimally invasive procedures

Surgeons at the Cedars-Sinai Institute for Spinal Disorders describe in the August 1 issue of the journal Spine a minimally invasive approach that enables them to perform fusion surgery on the difficult-to-access upper lumbar region of the spine with a reduced risk of serious complications.

2 Aug 2004

The p53 transcription factor plays a vital role in preventing cancer onset

Researchers at the Uppsala Branch of the Ludwig Institute for Cancer Research have discovered that the transcription factor Yin Yang 1 (YY1) is a novel regulator of the tumor suppressor p53, which is inactivated in at least half of all human cancers.

2 Aug 2004

Hypnotherapy for quitting smoking more effective in men

Hypnotherapy when used to quit smoking is more likely to be effective for men than women.

31 Jul 2004

Warning for counterfeit drugs simvastatin and carisoprodol recently imported from Mexico

The U.S. Food and Drug Administration has issued a public warning regarding counterfeit versions of the drugs simvastatin and carisoprodol that have recently been imported from Mexico to the U.S.

31 Jul 2004

Study shows blood transfusions during heart surgery appear to increase death risk

Patients who received blood platelet transfusions during coronary bypass surgery were more likely to have prolonged hospital stays, longer surgeries, more bleeding and higher risk of infection, stroke and death, according to an international study led by the Virginia Commonwealth University Medical Center.

29 Jul 2004

Under a third (31%) of all patients with type 2 diabetes are being managed by diet only

Results of a UK study in this week’s issue of THE LANCET highlight how people with diabetes controlled by diet alone have significant rates of complications and are less likely than patients on medication to be adequately monitored.

29 Jul 2004

Therapy News and Research

Entirely new approach to the treatment of aging

Third of heart failure patients face increased risk of death because they do not receive an angiotensin-converting enzyme (ACE) inhibitor

CV Therapeutics initiates approval-enabling trial of drug to treat chronic angina

New Drug Application with the U.S. Food and Drug Administration for Tarceva

Recommendation against the use of chemotherapy sensitivity and resistance assays

Adhering to established guidelines improves survival and reduces the risk of breast cancer

Home test kit for common sexually transmitted diseases

One-third of U.S. adults use some form of alternative medicine

Smart gene therapy might effectively prevent the organ damage commonly suffered by heart attack victims

Mining giant Rio Tinto has developed and implemented a global HIV/AIDS strategy

Inexpensive generic three-in-one fixed-dose combination pill taken twice a day has helped HIV/AIDS patients in Uganda

New approach to cancer vaccines may eradicate skin cancer tumors

Clinical benefit for moderate-to-severe plaque psoriasis patients treated with Raptiva for 30 months

Negative side effects of iron for people with kidney disease

A more direct lateral approach to minimally invasive procedures

The p53 transcription factor plays a vital role in preventing cancer onset

Hypnotherapy for quitting smoking more effective in men

Warning for counterfeit drugs simvastatin and carisoprodol recently imported from Mexico

Study shows blood transfusions during heart surgery appear to increase death risk

Under a third (31%) of all patients with type 2 diabetes are being managed by diet only

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