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Cell death in sparrow brains may provide clues in age-related human diseases

A remarkable change takes place in the brains of tiny songbirds every year, and some day the mechanism controlling that change may help researchers develop treatments for age-related degenerative diseases of the brain such as Parkinson's and dementia.

18 Sep 2007

New material for joint replacement and other implants

For orthopaedic implants to be successful, bone must meld to the metal that these artificial hips, knees and shoulders are made of.

18 Sep 2007

The importance of gene regulation for common human disease

A new study published in Nature Genetics on Sunday 16 September 2007 show that common, complex diseases are more likely to be due to genetic variation in regions that control activity of genes, rather than in the regions that specify the protein code.

17 Sep 2007

Scientists synthesize DNA-based memory loop in yeast cells

Harvard Medical School researchers have successfully synthesized a DNA-based memory loop in yeast cells, findings that mark a significant step forward in the emerging field of synthetic biology.

17 Sep 2007

Solid state NMR spectroscopy reveals the workings of 'Mother Nature's Blowtorch'

Using atom-level imaging techniques, University of Michigan researchers have revealed important structural details of an enzyme system known as "Mother Nature's blowtorch" for its role in helping the body efficiently break down many drugs and toxins.

17 Sep 2007

TFAP2C gene may be useful target for new breast cancer therapies

University of Iowa researchers have discovered a gene that plays a linchpin role in the ability of breast cancer cells to respond to estrogen.

17 Sep 2007

Immune system police recognize good and bad guys in the body

Immune system police are as good at recognizing bad guys, such as bacteria and viruses, as they are our own tissue, researchers say.

17 Sep 2007

DNA as a picoforce standard

DNA, the biomolecule that provides the blueprint for life, has a lesser-known identity as a stretchy polymer.

17 Sep 2007

Dendritic cells turn T cells into T regs

Regulatory T cells (also known as T regs) suppress some of the immune system's more inappropriate responses, preventing it from attacking the body's own tissues and stifling its activity once invading microbes have been fought off.

17 Sep 2007

Byproduct of cholesterol metabolism blocks heart health benefits of estrogen

New findings by UT Southwestern Medical Center researchers show that a byproduct of cholesterol metabolism interferes with the beneficial effects estrogen has on the cardiovascular system, providing a better understanding of the interplay between cholesterol and estrogen in heart disease.

17 Sep 2007

Researchers look at role of oxidative stress in human diseases

Oxidative stress is known to underlie many human diseases including atherosclerosis, Parkinson's disease and Alzheimer's disease.

17 Sep 2007

Ringxiety - phantom rings from your cell phone

A new study found that two thirds of the people surveyed, reported hearing their phone ring or feeling it vibrate when it had not actually rung.

17 Sep 2007

N-cofilin molecule protects from neuronal disorders

Many neuronal disorders, including epilepsy, schizophrenia and lissencephaly – a form of mental retardation - result from abnormal migration of nerve cells during the development of the brain.

17 Sep 2007

Byproduct of cholesterol interferes with the beneficial effects of estrogen on the heart

A new study possibly offers a biological reason why hormone replacement therapy (HRT) fails to protect some postmenopausal women from heart disease.

17 Sep 2007

Zebrafish shed light on human mitochondrial diseases

Zebrafish can now be used to study COX deficiencies in humans, a discovery that gives scientists an unprecedented window to view the earliest stages of mitochondrial impairments that lead to potentially fatal metabolic disorders, according to researchers at the University of Oregon.

13 Sep 2007

Potential solution to Candida parapsilosis infection

Infection with the fungus Candida parapsilosis is a major problem for individuals in intensive care units, as well as for premature infants and immunocompromised adults.

13 Sep 2007

Study suggests brain tumors need treatment with multiple 'targeted' drugs

Researchers at Dana-Farber Cancer Institute have shown that several, rather than just one, cell-growth switches are simultaneously overactive in many brain tumors and other solid tumors, explaining why treatment with just a single "targeted" switch-blocking drug often yields disappointing results.

13 Sep 2007