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Gut microbiome may promote pancreatic cancer by inducing immune suppression

Bacterial load was significantly higher in pancreatic tumor samples from patients with pancreatic ductal adenocarcinoma compared with pancreatic tissue from normal individuals, and in studies using mice, eliminating certain "bad" bacteria slowed the growth of pancreatic cancer, reversed immune suppression, and upregulated the immune checkpoint protein PD1.

22 Mar 2018

New ocular inserts allow patient's cornea to absorb more antibiotics

The anatomic and physiologic structure of the eyes constitutes by itself an important barrier when administering medicine. The amount of medicine that passes through the cornea by applying creams or drops is very limited and it is necessary to develop alternative, more effective ways of administering them ocularly.

22 Mar 2018

Research offers new understanding about cause of Parkinson's disease

Until very recently, Parkinson's had been thought a disease that starts in the brain, destroying motion centers and resulting in tremors and loss of movement.

21 Mar 2018

High-fat, high-cholesterol diet depletes ranks of artery-protecting immune cells

New research from scientists at the La Jolla Institute for Allergy and Immunology shows how a diet high in fat and cholesterol depletes the ranks of artery-protecting immune cells, turning them into promoters of inflammation, which exacerbate atherosclerotic plaque buildup that occurs in cardiovascular disease.

21 Mar 2018

Antibiotics could benefit women suffering from chronic bladder pain

Antibiotics can successfully help rid a patient of chronic urinary tract infection symptoms. This is the finding of a new clinical study led by Sheela Swamy of University College London in the UK.

20 Mar 2018

Scientists uncover new answers to cell aging in children with rare, fatal disease

In a recent paper published in Cell Reports, Saint Louis University researchers have uncovered new answers about why cells rapidly age in children with a rare and fatal disease.

20 Mar 2018

HORIBA's Microsemi CRP analyzer improves quality of care in emergency pediatric units, study shows

HORIBA UK Ltd, Medical announces that in a study recently undertaken and published as a case study by the Oxford Academic Health Science Network, its Microsemi CRP point-of-care (POC) analyzer was found to enable more rapid clinical decision-making, saving time and reducing costs, in emergency pediatric units.

From HORIBA Medical 20 Mar 2018

Artificial sweetener sucralose worsens gut inflammation in mice with Crohn's disease

In a study that has implications for humans with inflammatory diseases, researchers from Case Western Reserve University School of Medicine and colleagues have found that, given over a six-week period, the artificial sweetener sucralose, known by the brand name Splenda, worsens gut inflammation in mice with Crohn's-like disease, but had no substantive effect on those without the condition.

15 Mar 2018

Scientists develop rapid test that could revolutionize diagnostics of infectious diseases

Scientists of the Leibniz-Institute of Photonic Technologies, Center for Sepsis Control and Care at the University Hospital Jena and Friedrich Schiller University work at a faster and cheaper alternative for hitherto time consuming pathogen diagnostics.

14 Mar 2018

Toothpastes alone cannot protect against dental erosion and hypersensitivity

The rising prevalence of dental erosion and dentin hypersensitivity has led to the emergence of more and more toothpastes on the market that claim to treat these problems. While no such toothpaste existed 20 years ago, today, many brands with different attributes are being offered.

14 Mar 2018

Study uses ACEA Biosciences’ xCELLigence assay to monitor disruption of S. aureus biofilms

Biofilms are surface-attached communities of bacterial or fungal cells that are enmeshed in an extensive extracellular matrix which makes them more resistant to both antibiotics and the immune system.

13 Mar 2018

Researchers identify salivary protein that protects the body from traveler's diarrhea

Researchers have identified a protein in saliva (histatin-5) that protects the body from traveler's diarrhea.

8 Mar 2018

New class of antimicrobial polymers can kill five hard-to-treat multidrug-resistant bacteria

An international research team led by the Institute of Bioengineering and Nanotechnology of the Agency for Science, Technology and Research and IBM Research developed a synthetic molecule that can kill five deadly types of multidrug-resistant bacteria with limited, if any, side effects.

7 Mar 2018

Research shows how interaction between nervous and immune systems occurs in lung infections

When the body is fighting infection, the immune system kicks into high gear. But emerging evidence hints at the involvement of another, rather surprising, player in this process: the nervous system.

5 Mar 2018

Researchers report functional and transferable gene responsible for colistin resistance

A researcher at LSTM, working with a team of Chinese investigators, have reported that the gene responsible for resistance to a last resort antibiotic, colistin, is functional and transferable in Shigella flexneri, one of the leading causes of diarrhea worldwide.

2 Mar 2018

Scientists identify single genetic change in Salmonella that plays key role in bloodstream infections

Scientists have identified a single genetic change in Salmonella that is playing a key role in the devastating epidemic of bloodstream infections currently killing around 400,000 people each year in sub-Saharan Africa.

1 Mar 2018

Bacteria in humans and animals continue to show high levels of antimicrobial resistance

Bacteria from humans and animals continue to show resistance to antimicrobials, according to a new report published today by the European Food Safety Authority and the European Centre for Disease Prevention and Control.

28 Feb 2018

Researchers devise novel approach to develop antibacterial drugs

Researchers at VIB, KU Leuven and UZ Leuven devised a novel approach to develop antibacterial drugs. With antibiotic resistance on the rise worldwide, such new drugs are urgently needed. The Flemish biotech spin-off Aelin Therapeutics will exploit the technology to produce new antibiotics for the clinic.

28 Feb 2018

Study finds high rate of neonatal infections in Madagascar

Every year in the world, 4 million children die before the age of one, mainly in resource-limited countries, one-third of them due to a severe infection. The neonatal period alone (first month of life) accounts for one third of deaths before the age of one.

27 Feb 2018

Scientists reveal new insights into mechanism of gene regulation by 'magic spot'

Using an innovative crystallization technique for studying three-dimensional structures of gene transcription machinery, an international team of researchers, led by scientists at Penn State, has revealed new insights into the long debated action of the "magic spot"--a molecule that controls gene expression in Eschericahia coli and many other bacteria when the bacteria are stressed.

24 Feb 2018