Protein C News and Research

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'Guard mechanism' discovered for protein that attacks microbes in infected cells

Researchers have identified a 'guard mechanism' for a protein which attacks microbes in infected cells, opening the possibility of new treatments for Toxoplasma, Chlamydia, Tuberculosis and even cancer.

5 Oct 2023

Researchers spearhead a new method to hone in on new cancer drug targets

Searching for new ways to block the growth of cancer cells is like looking for a needle in a haystack. Tumor cells rely on thousands of proteins to function, but only a few of those proteins can be precisely targeted by drugs to treat cancer safely and effectively.

5 Oct 2023

Blood test for pan-cancer biomarker could revolutionize early cancer detection

Diagnostic tools for timely, accurate and inexpensive early cancer detection that can assess risk or monitor response to treatment could help patients get the care they need faster and improve existing care strategies.

5 Oct 2023

Artificial life forms could be used in the future for diagnosing and treating diseases

Creating artificial life is a recurring theme in both science and popular literature, where it conjures images of creeping slime creatures with malevolent intentions or super-cute designer pets.

5 Oct 2023

Unlocking the future of cancer care: Overcoming challenges in personalized neoantigen vaccine development

Challenges associated with the development and design of neoantigen cancer vaccines.

5 Oct 2023

Progress and challenges in completing the human gene catalogue

A group of authors reviewed the progress and challenges in annotating the human genome, including protein-coding genes, isoforms, and non-coding RNAs, and advocated for a universal annotation standard for clinical use.

5 Oct 2023

New nasal vaccine shows promise in preventing deadly Strep A infections

As Streptococcus A cases continue to be prevalent in Queensland and internationally, a new nasal vaccine could provide long-term protection from the deadly bacteria.

4 Oct 2023

Newly identified protein markers could signal early development of metastatic lung cancer

Researchers at Mays Cancer Center at The University of Texas Health Science at San Antonio (UT Health San Antonio) have identified protein markers that could signal for early development of metastatic lung cancer, providing possibilities for new treatment.

4 Oct 2023

Organ-on-chip model sheds light on lymphedema

In a new PNAS study co-authored by Boston University biomedical engineer Dr. Chris Chen, researchers say they're getting closer to understanding the mysteries of lymphedema - a condition characterized by the buildup of fluid in the body due to a malfunctioning lymphatic system.

4 Oct 2023

How vitamin D and genetics shape early brain development

The study examined how vitamin D levels and vitamin D binding protein genotypes in both pregnant mothers and their children aged 3-5, impact early childhood neurodevelopment. Findings suggest that higher vitamin D concentrations in children were associated with better neurodevelopmental scores, with additional influences from sociodemographic factors and certain genetic variations.

4 Oct 2023

Graphene oxide nanoflakes may help treat Alzheimer's disease

A probable early driver of Alzheimer's disease is the accumulation of molecules called amyloid peptides. These cause cell death, and are commonly found in the brains of Alzheimer's patients.

4 Oct 2023

Dietary deep dive: Unveiling the good, the bad, and the unclear in blood pressure battleground

An umbrella review in Advances in Nutrition critically analyzes various dietary elements' effects on blood pressure and hypertension, revealing a spectrum of impacts across different food groups and nutrients. While certain diets and foods like DASH, ketogenic, and flaxseed show promise in blood pressure control, the evidence varies widely, urging further research to refine existing hypertension dietary guidelines.

4 Oct 2023

Selective removal of aging cells represents a new paradigm for treating age-related diseases

A research team, led by Professor Ja Hyoung Ryu from the Department of Chemistry at UNIST, in collaboration with Professor Hyewon Chung from Konkuk University, has achieved a significant breakthrough in the treatment of age-related diseases.

4 Oct 2023

Early metformin therapy falls short in curbing gestational diabetes woes

In a significant randomized clinical trial, early metformin therapy was tested for its potential to lessen insulin dependence and enhance glycemic control in gestational diabetes-afflicted pregnant women; however, it yielded no improvements in diabetes symptoms. While metformin reduced maternal weight gain, its effects on primary diabetes symptoms and other secondary outcomes like infant weight gain were mixed, indicating a need for further focused research to unravel these associations.

4 Oct 2023

Effectiveness of Lactobacillus in treating inflammatory bowel disease

The role of Lactobacillus in treating inflammatory bowel disease.

4 Oct 2023

Wood cookstove use linked to gastric cancer risk

Researchers conducted a population-based study with a case–control design in rural areas of Honduras in Central America to examine whether wood cookstove use by indigenous populations was associated with increased risk of stomach cancers, including gastric adenocarcinoma.

4 Oct 2023

Trametinib: Potential therapeutic game-changer for Alzheimer's disease

Researchers developed the ATRIVIEW® platform to screen for molecules that promote differentiation neural stem cells (NSCs).

4 Oct 2023

Study reveals link between CHD8 gene, gut abnormalities, and autism-related behaviors

The connection between the CHD gene and autism-related gastrointestinal (GI) manifestations.

4 Oct 2023

Ubiquigent collaborates with Imperial College London on DUB probe discovery to facilitate preclinical and clinical target engagement studies

Ubiquigent Limited (Ubiquigent), a drug discovery and development company harnessing novel deubiquitinase (DUB) modulators as new therapeutics for areas of high unmet medical need, today announced it is supporting a PhD student in the Institute of Chemical Biology EPSRC Centre for Doctoral Training (CDT) in Chemical Biology, at Imperial College London.

From Ubiquigent Limited 4 Oct 2023

AI tool PARMESAN predicts drug-gene interactions for genetic disorders

To discover new treatments for genetic disorders, scientists need a thorough knowledge of prior literature to determine the best gene/protein targets and the most promising drugs to test.

3 Oct 2023

Protein C News and Research

'Guard mechanism' discovered for protein that attacks microbes in infected cells

Researchers spearhead a new method to hone in on new cancer drug targets

Blood test for pan-cancer biomarker could revolutionize early cancer detection

Artificial life forms could be used in the future for diagnosing and treating diseases

Unlocking the future of cancer care: Overcoming challenges in personalized neoantigen vaccine development

Progress and challenges in completing the human gene catalogue

New nasal vaccine shows promise in preventing deadly Strep A infections

Newly identified protein markers could signal early development of metastatic lung cancer

Organ-on-chip model sheds light on lymphedema

How vitamin D and genetics shape early brain development

Graphene oxide nanoflakes may help treat Alzheimer's disease

Dietary deep dive: Unveiling the good, the bad, and the unclear in blood pressure battleground

Selective removal of aging cells represents a new paradigm for treating age-related diseases

Early metformin therapy falls short in curbing gestational diabetes woes

Effectiveness of Lactobacillus in treating inflammatory bowel disease

Wood cookstove use linked to gastric cancer risk

Trametinib: Potential therapeutic game-changer for Alzheimer's disease

Study reveals link between CHD8 gene, gut abnormalities, and autism-related behaviors

Ubiquigent collaborates with Imperial College London on DUB probe discovery to facilitate preclinical and clinical target engagement studies

AI tool PARMESAN predicts drug-gene interactions for genetic disorders

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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