Receptor News and Research

RSS

SARS-CoV-2 Omicron variant binding to its receptor and therapeutic entities

Researchers generated a set of computed structural models of the Omicron receptor-binding domain attached to its receptor angiotensin-converting enzyme.

15 Dec 2021

Monoclonal antibody activity against SARS-CoV-2 Omicron variant

Scientists from Germany have recently pointed out that the third booster dose of mRNA-based COVID-19 vaccine is highly effective in neutralizing the omicron variant of SARS-CoV-2.

15 Dec 2021

Structure of human receptor and Omicron variant

Researchers studied the complex structure of the receptor-binding domain of the omicron variant with the human host receptor angiotensin-converting enzyme 2.

15 Dec 2021

Study provides new insights into molecular drivers of treatment resistance in prostate cancer

An international research team co-led by scientists at Roswell Park Comprehensive Cancer Center and The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute has identified an important accelerator of treatment-resistant prostate cancer.

14 Dec 2021

Omicron evades immunity more than other SARS-CoV-2 variants

Researchers find that the SARS-CoV-2 Omicron variant shows a much more extensive escape from vaccine-elicited immunity.

14 Dec 2021

Salk study could help find better treatment options for colorectal cancer patients

Patients with colorectal cancer were among the first to receive targeted therapies. These drugs aim to block the cancer-causing proteins that trigger out-of-control cell growth while sparing healthy tissues.

14 Dec 2021

11 exceptional recipients of the 2021 Lupus Innovation Award announced

The Lupus Research Alliance proudly announced today 11 research grant recipients in the U.S. and around the world of the 2021 Lupus Innovation Award which will fund wide ranging areas from probing the development and progression of lupus to pointing to potential personalized therapies.

14 Dec 2021

"Supermere" discovery may offer clues to earlier diagnoses and treatment of several diseases

Researchers at Vanderbilt University Medical Center have discovered a nanoparticle released from cells, called a "supermere," which contains enzymes, proteins and RNA associated with multiple cancers, cardiovascular disease, Alzheimer's disease and even COVID-19.

14 Dec 2021

Vaccinated seropositive individuals are able to induce high anti-spike SIgA responses

Results of a new study show that the induction of anti-SARSCoV-2 spike saliva SIgA antibodies after vaccination is independent of the gender or type of vaccine received.

14 Dec 2021

Assay for the identification of SARS-CoV-2 Spike reactive T and B cells

An interesting new paper presents a new assay for B and T lymphocytes in individuals infected with SARS-CoV-2.

14 Dec 2021

New mRNA vaccine platform provides stronger protection against SARS-CoV-2 delta variant

A group of researchers from various institutions developed a nucleoside-modified mRNA vaccine that encodes the SARS-CoV-2 N protein (mRNA-N) and is formulated in lipid nanoparticles for this investigation (LNP).

14 Dec 2021

Machine learning method for determining impact of mutations in the SARS-CoV-2 RBD on binding and antibody escape

Deep mutational learning (DML) is a technique developed by researchers from multiple institutions that combines experimental yeast display screening of RBD mutagenesis libraries with deep sequencing and machine learning.

14 Dec 2021

Omicron variant may strike double vaccinated

Largely, scientists are skeptical that the Omicron variant can infect vaccinated individuals. However, a new study published on the medRxiv* preprint server has conducted neutralization assays using an Omicron isolate obtained from patients residing in the United Kingdom.

13 Dec 2021

Lymphoma patients can benefit from early CAR T treatment, study shows

Chimeric antigen receptor T-cell therapy or CAR T is a breakthrough treatment for patients with certain types of blood cancers.

13 Dec 2021

Determination of the effectiveness of COVID-19 vaccination using T cell receptor repertoire

A new study published on the bioRxiv preprint server has hypothesized that T cell receptors (TCR) repertoire can measure the response to vaccines, as it would identify the TCR of clones that respond to the vaccination.

13 Dec 2021

$Study finds new treatment option for patients with relapsed or refractory peripheral T-cell lymphoma$

Study finds new treatment option for patients with relapsed or refractory peripheral T-cell lymphoma

The final results from a national phase 2 study including researchers from Yale Cancer Center show the drug tipifarnib increased survival rates for patients with relapsed or refractory peripheral T-cell lymphoma (PTCL).

13 Dec 2021

Study offers new hope for large B-cell lymphoma patients

Of the 18,000 people diagnosed with large B-cell lymphoma each year, only half will be successfully treated with chemotherapy. The 9,000 remaining patients typically have poor outcomes, with only 25% responding to additional, higher-intensity chemotherapy, followed by a stem cell transplant.

13 Dec 2021

Receptor News and Research

SARS-CoV-2 Omicron variant binding to its receptor and therapeutic entities

Monoclonal antibody activity against SARS-CoV-2 Omicron variant

Structure of human receptor and Omicron variant

Study provides new insights into molecular drivers of treatment resistance in prostate cancer

Omicron evades immunity more than other SARS-CoV-2 variants

Salk study could help find better treatment options for colorectal cancer patients

11 exceptional recipients of the 2021 Lupus Innovation Award announced

"Supermere" discovery may offer clues to earlier diagnoses and treatment of several diseases

Vaccinated seropositive individuals are able to induce high anti-spike SIgA responses

Assay for the identification of SARS-CoV-2 Spike reactive T and B cells

New mRNA vaccine platform provides stronger protection against SARS-CoV-2 delta variant

Machine learning method for determining impact of mutations in the SARS-CoV-2 RBD on binding and antibody escape

Omicron variant may strike double vaccinated

Lymphoma patients can benefit from early CAR T treatment, study shows

Determination of the effectiveness of COVID-19 vaccination using T cell receptor repertoire

Study finds new treatment option for patients with relapsed or refractory peripheral T-cell lymphoma

Study offers new hope for large B-cell lymphoma patients

Protein can protect the heart from damage following cancer treatment

Iota-carrageenan inhibits replication of SARS-CoV-2 VOCs

Novel assay using finger-prick samples provides COVID-19 vaccine efficacy data

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News