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FDA clears Sangamo BioSciences' SB-318 IND application for treatment of MPS I

Sangamo BioSciences, Inc., the leader in therapeutic genome editing, announced that the U.S. Food and Drug Administration has cleared the Company's Investigational New Drug (IND) application for SB-318, a single treatment strategy intended to provide a life-long therapy for Mucopolysaccharidosis Type I (MPS I).

8 Feb 2016

Positive data on ability of MyoKardia’s MYK-461 to prevent development of HCM published in Science

MyoKardia, Inc., a clinical stage biopharmaceutical company pioneering a precision medicine approach for the treatment of heritable cardiovascular diseases, today announced the publication of an article in the leading medical journal Science.

8 Feb 2016

Dnurse Glucose Meter and Dnurse app gain CE approval

Dnurse Technology has announced today that the Dnurse Glucose Meter and Dnurse app for Android and iOS have gained CE approval. It is the first CE approved smart glucose meter in China. CE (European Conformity) marking has been a mandatory conformity marking for certain products sold within the European Economic Area (EEA) since 1985.

8 Feb 2016

Aggression influences new nerve cell production in the brain

A group of neurobiologists from Russia and the USA, including Dmitry Smagin, Tatyana Michurina, and Grigori Enikolopov from Moscow Institute of Physics and Technology, have proven experimentally that aggression has an influence on the production of new nerve cells in the brain.

8 Feb 2016

LouLou Foundation, Penn Med set up Program of Excellence to develop treatments for children with CDKL5

The London-based LouLou Foundation and the Orphan Disease Center of the Perelman School of Medicine at the University of Pennsylvania have established a Program of Excellence to develop effective treatments for children with CDKL5, a rare X-chromosome-linked genetic disorder that causes severe neuro-developmental impairment and early-onset, difficult-to-control seizures.

8 Feb 2016

Loyola offers multidisciplinary digestive health program

Loyola University Health System now offers a multidisciplinary digestive health program to treat digestive tract and related medical conditions. Bipan Chand, MD, FACS, FASGE, FASMBS, and Neil Gupta, MD, MPH, are co-directors of the new program.

7 Feb 2016

New method could help physicians detect infection in wounds in less than a minute

A new method for detection of infection in wounds could take physicians less than a minute to complete, rather than the current 24 hours it takes to plate bacteria and leave it to incubate overnight, according to research by the George Washington University's Victoria Shanmugam, M.D.

7 Feb 2016

Scientists identify potential marker for recurring HPV-positive oropharyngeal cancer

A look-back analysis of HPV infection antibodies in patients treated for oropharyngeal (mouth and throat) cancers linked to HPV infection suggests at least one of the antibodies could be useful in identifying those at risk for a recurrence of the cancer, say scientists at The Johns Hopkins University.

7 Feb 2016

UIC researchers discover molecular switch that allows salmonella bacteria to fight immune system

Researchers at the University of Illinois at Chicago have discovered a molecular regulator that allows salmonella bacteria to switch from actively causing disease to lurking in a chronic but asymptomatic state called a biofilm.

7 Feb 2016

Scientists develop potential treatment to prevent hypertrophic cardiomyopathy

More than 15 years ago, David Warshaw, Ph.D., and coworkers discovered the precise malfunction of a specific protein in the heart that leads to hypertrophic cardiomyopathy, a common culprit in cases of sudden death in young athletes.

7 Feb 2016

Ambrisentan avoids sildenafil drug interaction in PAH patients

Sildenafil may be better given to pulmonary arterial hypertension patients in combination with ambrisentan than with bosentan, study findings suggest.

5 Feb 2016

$Falls, fractures may precede Parkinson’s disease by decades$

Falls, fractures may precede Parkinson’s disease by decades

People who later develop Parkinson’s disease have an increased tendency to fall and injure themselves, being at particular risk of hip fracture, a study shows.

5 Feb 2016

Duchenne muscular dystrophy: direct effect on muscle stem cells? An interview with Dr Rudnicki

For twenty years, it has been understood that dystrophin is expressed in differentiated muscle fibers where it is part of a protein complex that crosses the membrane and connects the extracellular matrix to the actin network inside the cell to provide structural integrity.

5 Feb 2016

UTHealth researchers demonstrate new way to reduce preterm birth

Using nanoparticles to engineer a special drug, a team of researchers from McGovern Medical School at The University of Texas Health Science Center at Houston has demonstrated in pre-clinical trials a new way to both reduce preterm birth and avoid the risks of medication in pregnancy to unborn babies.

5 Feb 2016

Better quality of care may reduce mortality risk in patients treated with opioid therapy for pain

Better quality of care may reduce the risk of death for patients who are prescribed opioid painkillers for chronic pain, say Yale researchers. Their study, published Feb. 4 in the Journal of General Internal Medicine, offers evidence that supports recommendations from clinical practice guidelines encouraging physicians to engage patients with mental health services and substance abuse treatment, as well as to avoid co-prescriptions for sedatives.

5 Feb 2016

Discovery takes researchers one step closer to preventing C. diff

Exposure to specific antibiotics is linked to the development of certain strains of antibiotic-resistant C. difficile, one of the fastest growing bacteria superbugs, according to a new study published by Stuart Johnson, MD, of Loyola University Health System, Loyola University Chicago Stritch School of Medicine and the Hines VA Medical Hospital.

5 Feb 2016

Intense physical work helped Michelangelo combat arthritis

Prolonged hammering and chiselling accelerated degenerative arthritis in the hands of Michelangelo Buonarroti, sculptor, painter and one of the greatest artists of all time. But the intense work probably helped him keep the use of his hands right up until he died. That is the conclusion of doctors writing in the Journal of the Royal Society of Medicine who analysed three portraits of the artist to reach their diagnosis.

5 Feb 2016

Lamin nucleoskeleton disordered in Alzheimer's

Brain cell death in Alzheimer's disease is linked to disruption of a skeleton that surrounds the nucleus of the cells, a researcher in the School of Medicine at The University of Texas Health Science Center at San Antonio said.

5 Feb 2016

New AGS guidance aims to transform approaches to healthcare for older patients

New guidance from the American Geriatrics Society aims to transform approaches to healthcare for our increasingly diverse older population. Developed by a committee of experts in ethnogeriatrics (the study of how ethnicity and culture impact the health and well-being of older people), "Achieving High-Quality Multicultural Geriatric Care" outlines present health disparities and the need for sensitivity to culture and health literacy when working with older individuals.

5 Feb 2016

African-American patients with connective tissue diseases at risk for cardiovascular disease

A study based on medical records from more than a quarter million adult patients found that African-American patients with connective tissue diseases such as lupus or rheumatoid arthritis were twice as likely as white patients to suffer from narrowed or atherosclerotic blood vessels, which increase the risk of a heart attack, stroke or death.

5 Feb 2016

Medicine News and Research

FDA clears Sangamo BioSciences' SB-318 IND application for treatment of MPS I

Positive data on ability of MyoKardia’s MYK-461 to prevent development of HCM published in Science

Dnurse Glucose Meter and Dnurse app gain CE approval

Aggression influences new nerve cell production in the brain

LouLou Foundation, Penn Med set up Program of Excellence to develop treatments for children with CDKL5

Loyola offers multidisciplinary digestive health program

New method could help physicians detect infection in wounds in less than a minute

Scientists identify potential marker for recurring HPV-positive oropharyngeal cancer

UIC researchers discover molecular switch that allows salmonella bacteria to fight immune system

Scientists develop potential treatment to prevent hypertrophic cardiomyopathy

Ambrisentan avoids sildenafil drug interaction in PAH patients

Falls, fractures may precede Parkinson’s disease by decades

Duchenne muscular dystrophy: direct effect on muscle stem cells? An interview with Dr Rudnicki

UTHealth researchers demonstrate new way to reduce preterm birth

Better quality of care may reduce mortality risk in patients treated with opioid therapy for pain

Discovery takes researchers one step closer to preventing C. diff

Intense physical work helped Michelangelo combat arthritis

Lamin nucleoskeleton disordered in Alzheimer's

New AGS guidance aims to transform approaches to healthcare for older patients

African-American patients with connective tissue diseases at risk for cardiovascular disease

Everything there is to know about biosimilars eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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