Malignant News and Research

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New tool that may prove to be invaluable for investigating the long-term mutagenic effects of chemotherapy and radiation

Scientists have developed a new tool that may prove to be invaluable for investigating the long-term mutagenic effects of chemotherapy and radiation, therapies that are widely used for the treatment of cancer.

17 Oct 2005

Discovery could help make cellular immunotherapy safer

Researchers at the University of Michigan's Comprehensive Cancer Center have discovered the secret weapon behind the most powerful form of cancer immunotherapy known to medicine.

16 Oct 2005

E-cadherin, that cellular touch so important in cancer

E-cadherin is a molecule involved in adhesion between epithelial cells that also seems to have a protective role in cancer, since its loss is associated with tumour progression and metastases formation in a series of different cancers.

16 Oct 2005

Chromosomes in the nucleus of the cell carry the material of heredity, or genes

Abnormal cell division that yields cells with an extra set of chromosomes can initiate the development of tumors in mice, researchers at Dana-Farber Cancer Institute have shown, validating a controversial theory about cancer causation put forth by a scientific visionary nearly 100 years ago.

12 Oct 2005

New monoclonal antibody that targets immune system B cells shows promise for treating leukemias

In studies with mice, treatment with a new monoclonal antibody that targets immune system B cells has shown considerable promise for treating leukemias, autoimmune diseases and transplant rejection, according to immunologists at Duke University Medical Center.

11 Oct 2005

CT colonography best choice for regular screening for cancer

Colorectal cancer is the second leading cause of cancer deaths in most developed countries. Screening for colorectal malignancies and polyps (which frequently become cancerous) has been shown to lower the number of deaths from cancer. Most cancer societies and preventive task forces recommend regular screening for cancer of the colon.

10 Oct 2005

Important milestone towards more individually targeted and effective treatments for cancer patients

The research team has now identified crucial genes in a range of common cancers that have been reported to predict a patient's response to treatment. This follows the team's earlier success in studying a tumor suppressor gene associated with acute lymphoblastic leukaemia (ALL) in children.

9 Oct 2005

Veggies reduce the risk of developing lung cancer in smokers

Eating vegetables and other foods that have weak estrogen-like activity appears to reduce the risk of developing lung cancer in smokers - as well as in non-smokers, say researchers at The University of Texas M. D. Anderson Cancer Center.

27 Sep 2005

Combining optical tomography with standard ultrasound imaging can help distinguish early-stage breast cancer

A new study shows that combining a technology called optical tomography with standard ultrasound imaging can help distinguish early-stage breast cancer from non-cancerous lesions--and potentially reduce the number of breast biopsies performed. The study appears in the October issue of the journal Radiology.

27 Sep 2005

Work absence after breast cancer diagnosis

Breast cancer is a very common malignancy with serious health effects that often involves women in the prime of their lives. Drolet and colleagues report on the work experience of women recently diagnosed with breast cancer.

27 Sep 2005

Researchers at Johns Hopkins have identified three new genetic mutations in brain tumors

...a discovery that could pave the way for more effective cancer treatments.

27 Sep 2005

A new, less toxic way to treat malignant melanoma

A new, less toxic way to treat malignant melanoma (skin cancer) is being developed by medicinal chemists at Reading University. They have produced a range of prodrugs: compounds that offer the potential to be converted to toxic molecules only within the vicinity of tumours. These prodrugs aim to reduce the toxicity of treatment.

26 Sep 2005

Researchers have uncovered a significant contributing factor to interferon resistance of malignant melanoma cells

The finding represents a step forward in understanding the molecular events that govern the growth of this type of cancer and the changes in gene expression and cellular signaling that underlie resistance to established therapies.

26 Sep 2005

Link between tissue tension and tumor formation

Most investigations into cancer have focused on chemical signals, but a new research study provides rare insight into how mechanical force can regulate cellular behavior.

20 Sep 2005

Injury prevention could save Maryland at least $700 million per year

In 2003, the total estimated cost of injuries in Maryland due to lost productivity and premature mortality was $1.9 billion dollars.

19 Sep 2005

Study points to importance of MYC gene in cancer progression

The cancer gene MYC is among the most commonly overexpressed oncogenes in human cancers. Most human cancers demonstrate high levels of MYC or its biological partners, including those of the breast, ovaries, lung, prostate, and skin, as well as leukemias and lymphomas.

19 Sep 2005

Compounds found in broccoli, cauliflower, and watercress block lung cancer progression

A family of compounds found in cruciferous vegetables, such as broccoli, cauliflower, and watercress, blocked lung cancer progression in both animal studies and in tests with human lung cancer cells, report researchers from Georgetown University Medical Center and the Institute for Cancer Prevention.

19 Sep 2005

Malignant News and Research

New tool that may prove to be invaluable for investigating the long-term mutagenic effects of chemotherapy and radiation

Discovery could help make cellular immunotherapy safer

E-cadherin, that cellular touch so important in cancer

Chromosomes in the nucleus of the cell carry the material of heredity, or genes

New monoclonal antibody that targets immune system B cells shows promise for treating leukemias

CT colonography best choice for regular screening for cancer

Important milestone towards more individually targeted and effective treatments for cancer patients

Veggies reduce the risk of developing lung cancer in smokers

Combining optical tomography with standard ultrasound imaging can help distinguish early-stage breast cancer

Work absence after breast cancer diagnosis

Researchers at Johns Hopkins have identified three new genetic mutations in brain tumors

A new, less toxic way to treat malignant melanoma

Researchers have uncovered a significant contributing factor to interferon resistance of malignant melanoma cells

Link between tissue tension and tumor formation

Injury prevention could save Maryland at least $700 million per year

Study points to importance of MYC gene in cancer progression

Compounds found in broccoli, cauliflower, and watercress block lung cancer progression

New and unusual class of genes plays an important role in the development of chronic lymphocytic leukemia

Combining radiation, chemotherapy and liver transplantation increases survival in bile duct cancer patients

Translation elongation factor eEF1A2 is is a potential oncogene that is overexpressed in two-thirds of breast tumors

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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