immunity News and Research

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Researchers create a cell library to study how various sugars bind to and interact with receptors

Most infectious bacteria and viruses bind to sugars on the surface of our cells. Now researchers from the University of Copenhagen have created a library of tens of thousands of natural cells containing all the sugars found on the surface of our cells.

23 Apr 2021

Only one vaccine is OK for older teens. It’s also the hardest to manage in rural America.

As states expand covid-19 vaccine eligibility to allow shots for 16- and 17-year-olds, teens in rural America may have trouble getting them.

23 Apr 2021

The Native Antigen Company Launches SARS-CoV-2 Neutralisation Assay Development Kit

The Native Antigen Company today announced the launch of its SARS-CoV-2 Neutralisation Assay Development Kit.

From The Native Antigen Company 23 Apr 2021

Researchers identify natural molecule that blocks the binding of human antibodies to SARS-CoV-2

Researchers have found that a natural molecule can effectively block the binding of a subset of human antibodies to SARS-CoV-2. The discovery may help explain why some COVID-19 patients can become severely ill despite having high levels of antibodies against the virus.

23 Apr 2021

DNA vaccine candidate induces potent immunity, offers protective efficacy in non-human primate models

A synthetic DNA vaccine candidate for Middle East respiratory syndrome coronavirus (MERS-CoV) developed at The Wistar Institute induced potent immune responses and afforded protective efficacy in non-human primate (NHP) models when given intradermally in abbreviated, low-dose immunization regimen.

23 Apr 2021

Striking difference identified between mRNA vaccination vs. SARS-CoV-2 infection immune responses

A team of scientists from the United States has recently compared the immune response elicited by natural severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19) vaccination. Their findings reveal that, unlike vaccination, natural SARS-CoV-2 infection is associated with a robust interferon response together with an induction of cytotoxic gene expression in peripheral blood lymphocytes. The study is currently available on the medRxiv* preprint server.

22 Apr 2021

Preclinical study from NIH/Moderna: Correlates of SARS-CoV-2 immunity in non-human primates

Researchers in the United States have shown that the antibody response induced by the Moderna mRNA-1273 vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a correlate of immune protection against coronavirus disease 2019 (COVID-19) in non-human primates.

22 Apr 2021

Researchers discover molecule that provides dual protection against vascular inflammation

A multidisciplinary team of researchers from Duke-NUS Medical School and the Agency for Science, Technology and Research (A*STAR) in Singapore discovered a new mitochondrial peptide called MOCCI that plays an important role in regulating inflammation of blood vessel and immunity.

22 Apr 2021

New mathematical model predicts the spread of COVID-19

Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory and the University of Illinois Urbana-Champaign (UIUC) have developed a new mathematical model for predicting how epidemics such as COVID-19 spread.

22 Apr 2021

Cleaning frequency key to limiting SARS-CoV-2 spread at theme parks

A new preprint research paper provides some insights into how this may be done using computational modeling. The study, which appeared on the medRxiv server, deals with the mitigation strategies that must be implemented in order to contain the virus.

22 Apr 2021

SARS-CoV-2 infection induces polyfunctional antibodies that can destroy infected cells

Drawing on epidemiological field studies and the FrenchCOVID hospital cohort coordinated by Inserm, teams from the Institut Pasteur, the CNRS and the Vaccine Research Institute (VRI, Inserm/University Paris-Est Créteil) studied the antibodies induced in individuals with asymptomatic or symptomatic SARS-CoV-2 infection.

21 Apr 2021

Georgia State professor receives $2.3 million federal grant to study inflammation in infectious diseases

Dr. Jian-Dong Li, professor and director of the Institute for Biomedical Sciences at Georgia State University, has received a five-year, $2.3 million federal grant to study how overactive inflammatory response is caused in infectious diseases and to further develop novel anti-inflammatory therapeutics.

21 Apr 2021

Censorship or misinformation? Desantis and YouTube spar over Covid roundtable takedown.

In early April, YouTube took down a video featuring Florida Gov. Ron DeSantis and a group of controversial scientists at a March 18 coronavirus roundtable. The online video platform, owned by Google, cited as its rationale that the video contained false statements about the efficacy of children's mask-wearing.

21 Apr 2021

Can a single BNT162b2 vaccine dose confer protective immunity against SARS-CoV-2 variants?

A team of researchers in Germany aimed to determine if the Pfizer-BioNTech vaccine mRNA vaccine (also known as the BNT162b2 vaccine) induces robust antibody responses against emergent SARS-CoV-2 variants, including the United Kingdom (or B1.1.7) variant; the South African (or B.1.351) variant; and the Brazilian (or P.1) variant.

21 Apr 2021

Antibody response induced by mRNA vaccination differs from natural SARS-CoV-2 infection

Researchers tested the antibodies elicited from mRNA vaccination and compared them to those from natural SARS-CoV-2 infection. They found the vaccine did not have antibodies to the virus nucleocapsid protein but had potent RBD antibodies.

21 Apr 2021

SARS-CoV-2-associated ssRNAs trigger inflammation and immunity via toll-like receptors

Severe COVID-19 causes sepsis-like manifestations, intense lung injury, and multi-organ failure, all associated with the overproduction of pro-inflammatory cytokines. This "cytokine storm" directly correlates with poor prognosis in this subgroup of patients.

21 Apr 2021

immunity News and Research

Researchers create a cell library to study how various sugars bind to and interact with receptors

Only one vaccine is OK for older teens. It’s also the hardest to manage in rural America.

The Native Antigen Company Launches SARS-CoV-2 Neutralisation Assay Development Kit

Researchers identify natural molecule that blocks the binding of human antibodies to SARS-CoV-2

DNA vaccine candidate induces potent immunity, offers protective efficacy in non-human primate models

Striking difference identified between mRNA vaccination vs. SARS-CoV-2 infection immune responses

Preclinical study from NIH/Moderna: Correlates of SARS-CoV-2 immunity in non-human primates

Researchers discover molecule that provides dual protection against vascular inflammation

New mathematical model predicts the spread of COVID-19

Cleaning frequency key to limiting SARS-CoV-2 spread at theme parks

SARS-CoV-2 infection induces polyfunctional antibodies that can destroy infected cells

Georgia State professor receives $2.3 million federal grant to study inflammation in infectious diseases

Censorship or misinformation? Desantis and YouTube spar over Covid roundtable takedown.

Can a single BNT162b2 vaccine dose confer protective immunity against SARS-CoV-2 variants?

Antibody response induced by mRNA vaccination differs from natural SARS-CoV-2 infection

SARS-CoV-2-associated ssRNAs trigger inflammation and immunity via toll-like receptors

Children develop strong, long-lasting immunity following SARS-CoV-2 infection

Organ tissues become increasingly immune throughout life, new study suggests

Limited SARS-CoV-2 spread in childcare centers, finds study

Can an immunosuppressive cancer drug promote SARS-CoV-2 entry into host cells?

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