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KHN’s ‘What the Health?’: The autumn of Democrats’ discontent

Democrats in Congress and the White House are feverishly negotiating to pass as much of President Joe Biden's domestic agenda as they can agree on, even as Republicans who oppose much of the increased spending threaten to shut down the government and default on the nation's debt.

23 Sep 2021

Scientists characterize new genetic variants that cause nonsyndromic neurodevelopmental disorder

Northwestern Medicine scientists have characterized several variants of the gene GRIK2 that cause nonsyndromic neurodevelopmental disorder (NDD), according to a study published in the American Journal of Human Genetics.

23 Sep 2021

New discovery may offer a promising avenue for study of multiple sclerosis

A surprising discovery may offer a promising new direction in the study of multiple sclerosis and other diseases of hypomyelination – when axons of neurons are not covered sufficiently in fatty sheaths (myelin), which disrupts communication between nerve cells.

23 Sep 2021

People with natural immunity and subsequent mRNA vaccination can neutralize viral particles capable of resisting vaccine-induced antibodies

New research suggests SARS-CoV-2 spike protein substitution mutations can create a replication-defective viral particle that makes the virus resistant to vaccine-induced antibodies.

23 Sep 2021

Varying immune responses after single dose of Pfizer and AstraZeneca COVID-19 vaccines

A new preprint describes the significant variation in the early immune response elicited by two of the earliest vaccines to gain emergency authorization against COVID-19.

23 Sep 2021

Differences in blood gene expression among patients with varying COVID-19 severity

A new study published on the medRxiv* pre-print server and currently undergoing peer-review aims to answer this question through whole blood transcriptomics of individuals with varying degrees of COVID-19 severity. Transcriptomics, done by RNA sequencing, gives insights into the genes expressed in a cell at a given time point. It gives an analysis of all RNA molecules within a cell, in this case, whole blood.

23 Sep 2021

Long-term effects of COVID-19 in children

A recent preprint deals with the incidence and importance of long COVID in children.

23 Sep 2021

The checkup is in the mail? Soliciting letter carriers to help deliver health care

Two of America's toughest problems can be tempered with one solution. The baby boom generation is graying, creating an ever-larger population of older people, many isolated, whose needs the nation is ill equipped to meet or even monitor.

23 Sep 2021

Democrats roll the dice on sweeping abortion rights bill — again

A newly conservative Supreme Court agreed to hear a case most assumed it would use to overrule the 1973 landmark abortion-rights ruling, Roe v. Wade. And Democrats on Capitol Hill, convinced the issue would play to their political favor, vowed to bring up legislation that would write abortion protections into federal law.

23 Sep 2021

Biosimilar drugs are cheaper than biologics. Are they similar enough to switch?

It took years for Elle Moxley to get a diagnosis that explained her crippling gastrointestinal pain, digestion problems, fatigue, and hot, red rashes.

23 Sep 2021

Diabetes drug may help to prolong pregnancy in women with preterm pre-eclampsia

Giving the drug metformin to women diagnosed with preterm pre-eclampsia may help to prolong pregnancy (gestation), finds a study published by The BMJ today.

23 Sep 2021

Discovery points toward a new strategy for treating Parkinson's disease

University of Utah Health scientists have identified a molecule that slows cells' production of alpha-synuclein, a protein that forms toxic aggregates in the brains of people with Parkinson's disease.

23 Sep 2021

Scientists reveal the biological process leading to dangerous inflammatory disease in preemies

In a study with mice reported today in the journal Science Translational Medicine, a Johns Hopkins Medicine research team has provided what may be the most definitive view to date of the biological process leading to necrotizing enterocolitis (NEC), a dangerous inflammatory disease that can destroy a premature infant's intestinal lining and causes death in up to a third of the cases.

23 Sep 2021

Researchers apply deep learning to PS-OCT systems to better detect cancer

Yi "Edwin" Sun, a Ph.D. candidate in electrical and computer engineering at the University of Illinois Urbana-Champaign and member of the Beckman Institute's Biophotonics Imaging Laboratory headed by Stephen Boppart, explored how deep learning methods can make polarization-sensitive optical coherence tomography, or PS-OCT, more cost-effective and better equipped to diagnose cancer in biological tissues.

23 Sep 2021

COVID-19 pandemic has worsened food insecurity, especially in households with children

Nearly 15 percent of U.S. households - and nearly 18 percent of households with children - reported food insecurity early in the COVID-19 pandemic, according to a survey conducted via social media by researchers at NYU School of Global Public Health.

23 Sep 2021

Study provides clearer understanding of how migraines affect sleep patterns

Adults and children with migraines may get less quality, REM sleep time than people who don't have migraines.

23 Sep 2021

Scientists discover how mucus protein emerges to disrupt airways of individuals with lung conditions

Mucus is an essential protective layer of gel-like liquid composed largely of proteins called mucins throughout our airways. One of them, called MUC5B, is crucial for the innate defense against the various things we inhale.

23 Sep 2021

Neuroscientists discover how associative memories are formed

Has the scent of freshly baked chocolate chip cookies ever taken you back to afternoons at your grandmother's house? Has an old song ever brought back memories of a first date? The ability to remember relationships between unrelated items (an odor and a location, a song and an event) is known as associative memory.

23 Sep 2021

DNA sensor can detect infectious viruses in minutes

A new sensor can detect not only whether a virus is present, but whether it's infectious – an important distinction for containing viral spread.

23 Sep 2021

Study provides novel insights into how KLF4 influences gene expression

A team led by researchers at Baylor College of Medicine has discovered a mechanism by which transcription factor KLF4 can help to organize chromatin, thus influencing gene expression.

23 Sep 2021

Research News and Research

KHN’s ‘What the Health?’: The autumn of Democrats’ discontent

Scientists characterize new genetic variants that cause nonsyndromic neurodevelopmental disorder

New discovery may offer a promising avenue for study of multiple sclerosis

People with natural immunity and subsequent mRNA vaccination can neutralize viral particles capable of resisting vaccine-induced antibodies

Varying immune responses after single dose of Pfizer and AstraZeneca COVID-19 vaccines

Differences in blood gene expression among patients with varying COVID-19 severity

Long-term effects of COVID-19 in children

The checkup is in the mail? Soliciting letter carriers to help deliver health care

Democrats roll the dice on sweeping abortion rights bill — again

Biosimilar drugs are cheaper than biologics. Are they similar enough to switch?

Diabetes drug may help to prolong pregnancy in women with preterm pre-eclampsia

Discovery points toward a new strategy for treating Parkinson's disease

Scientists reveal the biological process leading to dangerous inflammatory disease in preemies

Researchers apply deep learning to PS-OCT systems to better detect cancer

COVID-19 pandemic has worsened food insecurity, especially in households with children

Study provides clearer understanding of how migraines affect sleep patterns

Scientists discover how mucus protein emerges to disrupt airways of individuals with lung conditions

Neuroscientists discover how associative memories are formed

DNA sensor can detect infectious viruses in minutes

Study provides novel insights into how KLF4 influences gene expression

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