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Individual genetic variations and bacterial flora linked to recurrent caries disease

Researchers at Umeå University have for the first time been able to show that individual variation in susceptibility to infection and bacterial flora together explain recurrent caries disease and that others are asymptomatic.

21 Feb 2024

Study reveals mechanism of drug targeting protein modification in tumor suppressor genes

Researchers have revealed the mechanism of a drug shown to be effective in treating certain types of cancer, which targets a protein modification silencing the expression of multiple tumor suppressor genes.

21 Feb 2024

Unlocking non-hormonal male contraception with HDAC inhibitors

Surveys show most men in the United States are interested in using male contraceptives, yet their options remain limited to unreliable condoms or invasive vasectomies.

20 Feb 2024

Early childhood food responsiveness may predict eating disorder symptoms

An enthusiastic response to food in early childhood may be linked to a higher likelihood of experiencing eating disorder symptoms in adolescence, according to a new study led by researchers at UCL and Erasmus University Rotterdam.

20 Feb 2024

Adopting key healthy behaviors reduces risk of irritable bowel syndrome

Adopting a healthy lifestyle is strongly linked to a lower risk of irritable bowel syndrome or IBS for short, finds research published online in the journal Gut.

20 Feb 2024

Study reveals low utilization of PCSK9 inhibitors in high-risk patients

A new study published in Circulation: Cardiovascular Quality and Outcomes from the Family Heart Foundation - a patient-centered research and advocacy nonprofit organization dedicated to improving the lives of families impacted by inherited lipid disorders and LDL-cholesterol - revealed that utilization of proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) to reduce low-density lipoprotein cholesterol (LDL-C) remains low among high-risk patients.

20 Feb 2024

Novel genetic locations associated with primary open-angle glaucoma identified

An international genetic study using multiancestry biobanks has identified novel genetic locations associated with primary open-angle glaucoma (POAG), the most common type of glaucoma and the leading cause of irreversible blindness globally.

20 Feb 2024

Study proposes novel approach to slow neuromuscular degeneration in ALS patients

A study led by the Center for Biomaterials and Tissue Engineering of the Universitat Politècnica de València, member of Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine, in collaboration with the Instituto de Investigación Sanitaria La Fe and the University of Zaragoza proposes a novel approach to slow neuromuscular degeneration in patients with Amyotrophic Lateral Sclerosis.

20 Feb 2024

Researchers develop novel nanomedicine loaded with genetic material to fight HIV

Society learned about the value of mRNA during the COVID-19 pandemic when we saw scientists and medical professionals harness its power to deliver a vaccine for the virus within a year.

20 Feb 2024

Study highlights health care disparities for Nunavik Inuit inhabitants with lung cancer

People living in the Inuit region of Nunavik in northern Quebec die earlier after a diagnosis of lung cancer than Montreal residents receiving treatment at the same cancer centre, according to new research published in CMAJ.

20 Feb 2024

NIH-funded research enhances genetic testing for health equity

To prevent an emerging genomic technology from contributing to health disparities, a scientific team funded by the National Institutes of Health has devised new ways to improve a genetic testing method called a polygenic risk score.

20 Feb 2024

Novel genetic associations with anxiety unveiled in comprehensive study of over 1.2 million people

The genetic basis of anxiety disorders, identify genetic loci, and calculate polygenic risk scores for anxiety.

20 Feb 2024

Sleep-circadian disturbances can trigger or worsen a range of psychiatric disorders

Problems with our sleep and internal body clock can trigger or worsen a range of psychiatric disorders, according to a new review of recent research evidence.

19 Feb 2024

Selection, optimization, and validation of genetic tests for 10 common diseases

By analyzing millions of small genetic differences across a person's genome, researchers can calculate a polygenic risk score to estimate someone's lifetime odds of developing a certain disease.

19 Feb 2024

Mapping the genomic landscape of Type 2 diabetes

In the largest genome-wide association study to date on Type 2 diabetes, a team of international researchers, co-led by a University of Massachusetts Amherst genetic epidemiologist, has located 1,289 genetic markers associated with Type 2 diabetes (145 of which are newly identified) and generated risk scores for diabetes complications.

19 Feb 2024

Study discovers link between a breakdown product from excess niacin and heart disease

Cleveland Clinic researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol.

19 Feb 2024

Study suggests high levels of vitamin B3 breakdown products are linked to higher risk of mortality, heart attacks, and stroke

Researchers utilized an untargeted metabolomics technique to look for new compounds and pathways that may contribute to residual cardiovascular disease risk.

19 Feb 2024

Identification of genetic determinants of micronucleus formation

The genetic determinants of micronuclei formation (MN).

19 Feb 2024

Single-dose genetic medicine halts the progression of ALS and frontotemporal dementia in mice

Neuroscientists at Macquarie University in Australia have developed a single-dose genetic medicine that has been proven to halt the progression of both ALS and frontotemporal dementia (FTD) in mice – and may even offer the potential to reverse some of the effects of the fatal diseases.

19 Feb 2024

Research demonstrates a bat species' resistance to cancer, pinpoints key genes

A study reveals Myotis pilosus bats exhibit exceptional cancer resistance through gene downregulation, offering insights into natural anticancer mechanisms.

18 Feb 2024

Genetic News and Research

Individual genetic variations and bacterial flora linked to recurrent caries disease

Study reveals mechanism of drug targeting protein modification in tumor suppressor genes

Unlocking non-hormonal male contraception with HDAC inhibitors

Early childhood food responsiveness may predict eating disorder symptoms

Adopting key healthy behaviors reduces risk of irritable bowel syndrome

Study reveals low utilization of PCSK9 inhibitors in high-risk patients

Novel genetic locations associated with primary open-angle glaucoma identified

Study proposes novel approach to slow neuromuscular degeneration in ALS patients

Researchers develop novel nanomedicine loaded with genetic material to fight HIV

Study highlights health care disparities for Nunavik Inuit inhabitants with lung cancer

NIH-funded research enhances genetic testing for health equity

Novel genetic associations with anxiety unveiled in comprehensive study of over 1.2 million people

Sleep-circadian disturbances can trigger or worsen a range of psychiatric disorders

Selection, optimization, and validation of genetic tests for 10 common diseases

Mapping the genomic landscape of Type 2 diabetes

Study discovers link between a breakdown product from excess niacin and heart disease

Study suggests high levels of vitamin B3 breakdown products are linked to higher risk of mortality, heart attacks, and stroke

Identification of genetic determinants of micronucleus formation

Single-dose genetic medicine halts the progression of ALS and frontotemporal dementia in mice

Research demonstrates a bat species' resistance to cancer, pinpoints key genes

Sequencing & Genomics: Elevating Science and Healthcare eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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