Membrane News and Research

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Biotech to the rescue

MIT professor Ram Sasisekharan's three biotech companies — Momenta Pharmaceuticals, Cerulean Pharma, and Visterra — share a similar goal.

1 May 2014

Support for internal limiting membrane peeling for full-thickness macular holes

Vitrectomy with peeling of the internal limiting membrane of the retina improves the outcome of idiopathic full-thickness macular hole surgery compared with no peeling, study findings show.

1 May 2014

Single treatment for AMD 'unlikely'

Age-related macular degeneration does not follow the same disease course from one patient to another, conclude researchers who suggest that phenotyping may be important before initiating a therapeutic trial.

1 May 2014

Researchers demonstrate possibility of using blood test to detect depression

Researchers at the MedUni Vienna have demonstrated the possibility of using a blood test to detect depression. While blood tests for mental illnesses have until recently been regarded as impossible, a recent study clearly indicates that, in principle, depression can in fact be diagnosed in this way and this could become reality in the not too distant future.

30 Apr 2014

Researchers identify genetic factors that contribute to ADHD in humans

The 60 trillion cells that comprise our bodies communicate constantly. Information travels when chemical compounds released by some cells are received by receptors in the membrane of another cell.

26 Apr 2014

Virginia Tech scientist receives grant to develop technique to detect subcellular location of protein

Virginia Tech chemical engineer Chang Lu and his colleagues have used a National Science Foundation grant to develop a technique to detect subcellular location of a protein.

26 Apr 2014

Researchers use RNA sequencing to look at early- and late-stage development of the heart

Most people think the development of the heart only happens in the womb, however the days and weeks following birth are full of cellular changes that play a role in the structure and function of the heart. Using mouse models, researchers at Baylor College of Medicine have now been able to categorize the alternative splicing (the process in which genes code proteins, determining their role) that takes place during these changes and what mechanisms they affect.

26 Apr 2014

Biologists identify how T-type channels change electrochemical signaling of heart and brain cells

Biologists have discovered how an outer shield over T-type channels change the electrochemical signaling of heart and brain cells. Understanding how these shields work will help researchers eventually develop a new class of drugs for treating epilepsy, cardiovascular disease and cancer.

26 Apr 2014

Study could lead to better understanding of how Notch protein directs healthy development of organs

Johns Hopkins researchers report they have figured out how the aptly named protein Botch blocks the signaling protein called Notch, which helps regulate development. In a report on the discovery, to appear online April 24 in the journal Cell Reports, the scientists say they expect the work to lead to a better understanding of how a single protein, Notch, directs actions needed for the healthy development of organs as diverse as brains and kidneys.

26 Apr 2014

French researchers introduce new method to effectively control bleeding and repair tissues

Stopping bleeding, closing wounds, repairing organs—these are everyday challenges in medical and surgical practice. In the journal Angewandte Chemie, French researchers have now introduced a new method that employs gluing by aqueous nanoparticle solutions to effectively control bleeding and repair tissues. In animal tests, their approach proved easy to apply, rapid and efficient even in situations when conventional methods are traumatic or fail.

25 Apr 2014

Noval neuroimaging technique enables detailed insights into mitochondria

Reactive oxygen species are important intracellular signaling molecules, but their mode of action is complex: In low concentrations they regulate key aspects of cellular function and behavior, while at high concentrations they can cause "oxidative stress", which damages organelles, membranes and DNA.

25 Apr 2014

CPX-351 treatment leads to higher chances of remission in AML patients, says study

Moffitt Cancer Center researchers say clinical trials for a new experimental drug to treat acute myeloid leukemia (AML) are very promising. Patients treated with CPX-351, a combination of the chemotherapeutic drugs cytarabine and daunorubicin, are showing better responses than patients treated with the standard drug formulation.

25 Apr 2014

TSRI scientists discover new HIV target

A team led by scientists at The Scripps Research Institute (TSRI) working with the International AIDS Vaccine Initiative (IAVI) has discovered a new vulnerable site on the HIV virus. The newly identified site can be attacked by human antibodies in a way that neutralizes the infectivity of a wide variety of HIV strains.

25 Apr 2014

TSRI scientists identify protein complex that plays critical role in learning and memory formation

Scientists from the Florida campus of The Scripps Research Institute have identified a protein complex that plays a critical but previously unknown role in learning and memory formation.

23 Apr 2014

Scientists develop DNA nanodevices that survive body's immune defenses

It's a familiar trope in science fiction: In enemy territory, activate your cloaking device. And real-world viruses use similar tactics to make themselves invisible to the immune system.

23 Apr 2014

Diaverum acquires its seventh kidney centre in Chile

Diaverum, one of the world's leading renal care service providers, has acquired its seventh kidney centre Chile. The Diaseal clinic, located in Puente Alto, a highly populated and fast growing district in the south of capital Santiago, features 18 stations which are used to treat 100 patients with haemodialysis (HD).

23 Apr 2014

Researchers develop first size-based form of chromatography using nanodot technology

Using nanodot technology, Berkeley Lab researchers have demonstrated the first size-based form of chromatography that can be used to study the membranes of living cells.

23 Apr 2014

Drug used to treat TB may also act against various infections, says study

A drug under clinical trials to treat tuberculosis could be the basis for a class of broad-spectrum drugs that act against various bacteria, fungal infections and parasites, yet evade resistance, according to a study by University of Illinois chemists and collaborators.

18 Apr 2014

Understanding GPCRs and controlling inflammation: an interview with Dr. Richard Proia, NIDDK, NIH

GPCRs are one of the largest families of cellular signalling proteins consisting of more than a thousand different types. They reside on the surface membranes of cells where they are poised to recognize molecules in the exterior environment and then transmit this information through the membrane allowing cells to respond accordingly.

16 Apr 2014

Protein expression predicts postop NSCLC recurrence, survival

US-based researchers have identified a panel of 12 proteins that may help predict overall survival and the risk of recurrence in patients treated with surgery for non-small-cell lung cancer.

15 Apr 2014

Membrane News and Research

Biotech to the rescue

Support for internal limiting membrane peeling for full-thickness macular holes

Single treatment for AMD 'unlikely'

Researchers demonstrate possibility of using blood test to detect depression

Researchers identify genetic factors that contribute to ADHD in humans

Virginia Tech scientist receives grant to develop technique to detect subcellular location of protein

Researchers use RNA sequencing to look at early- and late-stage development of the heart

Biologists identify how T-type channels change electrochemical signaling of heart and brain cells

Study could lead to better understanding of how Notch protein directs healthy development of organs

French researchers introduce new method to effectively control bleeding and repair tissues

Noval neuroimaging technique enables detailed insights into mitochondria

CPX-351 treatment leads to higher chances of remission in AML patients, says study

TSRI scientists discover new HIV target

TSRI scientists identify protein complex that plays critical role in learning and memory formation

Scientists develop DNA nanodevices that survive body's immune defenses

Diaverum acquires its seventh kidney centre in Chile

Researchers develop first size-based form of chromatography using nanodot technology

Drug used to treat TB may also act against various infections, says study

Understanding GPCRs and controlling inflammation: an interview with Dr. Richard Proia, NIDDK, NIH

Protein expression predicts postop NSCLC recurrence, survival

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