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Researchers use endocytic pathways to sort out NSCLC lines into two distinct clusters

In the Age of Personalized Medicine, we've learned that one size doesn't fit all, least of all in cancer. Cancer is a disease of your cells, and sorting out your cancer from all others is a daunting challenge but one that cancer cell biologists are furiously pursuing. They are examining every aspect of cell function and cell structure, looking for clusters of phenotypes that could label a patient's cancer so precisely that it could be linked to therapies proven effective against just that type.

12 Dec 2015

New research sheds light on outcomes for patients with thyroid cancer

Thyroid cancer survivors report poor quality of life after diagnosis and treatment compared with other patients who are diagnosed with more lethal cancers, according to new research from the University of Chicago Medicine.

12 Dec 2015

Nearly half of Muslim Americans face discrimination in health care workplace

While many studies have examined the impact of bias based on race, gender or sexual orientation, religious discrimination in the health care workplace has received little research attention. A new study funded by the John Templeton Foundation and conducted at the University of Chicago finds that for Muslim Americans, even those in one the nation's most highly regarded professions, encounter a less-than-inclusive and welcoming work environment during their career.

11 Dec 2015

Androgen deprivation therapy elevates Alzheimer’s risk

US researchers find that androgen deprivation therapy increases the risk of Alzheimer’s disease in men with prostate cancer, with the risk rising with greater duration of therapy.

11 Dec 2015

Mount Sinai scientists develop new tool to determine global role of microRNAs

As microRNA biology has been implicated in everything from the development of cancer to virus infections, a new tool developed by scientists at the Icahn School of Medicine at Mount Sinai holds tremendous potential to develop new therapies that involve these small regulatory fragments of RNA.

11 Dec 2015

Researchers find new method to create uniform standards in search for cancer-relevant mutations

Oncologists are increasingly using information obtained from investigations of the tumor genome in order to find individualized therapies for patients. They specifically search the hereditary information of cancer cells for mutations that drive malignant growth. By now, targeted drugs against many of these cancer-typical cellular alterations have become available.

11 Dec 2015

Pathologic complete response after presurgery chemotherapy increases overall survival for TNBC patients

Patients with stage 2 or stage 3 triple-negative breast cancer (TNBC) who had a pathologic complete response (pCR) after presurgery chemotherapy had increased event-free and overall survival compared with those who had more than minimal residual invasive disease at surgery following presurgery chemotherapy, according to results from the randomized phase II CALGB/Alliance 40603 clinical trial presented at the 2015 San Antonio Breast Cancer Symposium, held Dec. 8-12.

11 Dec 2015

Early life exposures to toxic chemicals reduce infants' response to TB vaccine

Early life exposures to toxic chemicals such as PCBs and DDT dampen an infant's response to the tuberculosis vaccine, according to a new study from the University of Rochester Environmental Health Sciences Center.

11 Dec 2015

UC San Diego's Comprehensive Stroke Center receives Gold Plus Award

When someone experiences a major stroke, almost two million nerve cells in the brain die each minute, emphasizing the need for rapid treatment. Stroke patients who receive life-saving interventions more quickly have a higher chance of recovery. A recent data analysis showed the Comprehensive Stroke Center at UC San Diego Medical Center exceeded national average treatment times, and as a result, has received a "Get With The Guidelines-Stroke Gold Plus Quality Achievement Award" from The American Heart Association and American Stroke Association.

11 Dec 2015

Discovery may provide reliable 'clock' for forensic scientists

Researchers at University of California, San Diego School of Medicine and University of Colorado Boulder have discovered that unique and changing microbial communities present during decomposition of human cadavers may provide a reliable "clock" for forensic scientists. The method could be used to estimate time of death in different seasons, as well determine the original location of moved corpses and help locate buried corpses.

11 Dec 2015

Study: Spanish-speaking Hispanic women less likely to use neuraxial analgesia during labor

Why do Hispanic women have reduced rates of epidural or spinal (neuraxial) analgesia during labor? Language barriers may be a key factor, according to a study in Anesthesia & Analgesia.

11 Dec 2015

Rowan University partners with DMHAS to provide treatment services for people with substance abuse disorders

The Department of Family Medicine at the Rowan University School of Osteopathic Medicine has entered into a two-year $973,000 agreement with the New Jersey Department of Human Services Division of Mental Health Addiction Services to provide early intervention and treatment services for individuals who have, or are at risk for, substance abuse disorders.

11 Dec 2015

New guidelines may help reduce medication use among seniors

We're not getting any younger. According to the Administration for Community Living, by 2060, there will be about 98 million older persons in the United States — more than twice their number in 2013.

11 Dec 2015

UB physicians testing new exercise treatment for concussion

The standard of care for acute concussion may undergo a dramatic change, depending on the results of a new exercise treatment that physicians at the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo have developed and begun testing. It is the first randomized, controlled clinical trial of this exercise treatment for concussion.

11 Dec 2015

Single dose of psilocybin decreases anxiety, depression in cancer patients

A single dose of psilocybin, the major hallucinogenic component in magic mushrooms, induces long-lasting decreases in anxiety and depression in patients diagnosed with life-threatening cancer according to a new study presented today at the annual meeting of the American College of Neuropsychopharmacology.

11 Dec 2015

Virologists demonstrate how poxviruses defeat the body's host immune defenses

Smallpox virus, which killed millions of humans through the ages, ranks among the world's most feared bioterrorism agents. Human monkeypox continues to occur sporadically in remote African villages.

11 Dec 2015

Providing novice surgeons with regular feedback can help prevent blood clots among hospitalized patients

A study of general surgery residents at The Johns Hopkins Hospital suggests that in the efforts to prevent dangerous blood clots among hospitalized patients, regular, one-on-one feedback and written report cards work a lot better than the usual group lectures that newly minted surgeons receive as part of their training.

11 Dec 2015