Antibiotic News and Research

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Antibiotics are drugs used to treat infections caused by bacteria and other microorganisms.

Enrollment of Phase 2 portion of Cempra Pharmaceuticals' Phase 2/3 clinical trial of TAKSTA completed

Cempra Pharmaceuticals today announced completion of enrollment of the Phase 2 portion of its Phase 2/3 clinical trial of TAKSTA (sodium fusidate; CEM-102) for the treatment of acute bacterial skin and skin structure infections.

19 Jan 2010

New insights into molecular interaction between probiotics and altered host intestinal ecosystem in IPAA

Total proctocolectomy with ileal J-pouch-anal anastomosis (IPAA) is the surgical treatment of choice for patients with refractory ulcerative colitis (UC). Although the surgery generally cures UC allowing a significant improvement of health-related quality of life, complications can occur after IPAA.

18 Jan 2010

Also in Global Health News: Family planning in Philippines; drug pricing in Africa

A government survey in the Philippines "found 73 percent of married women would use birth control if it were available, 22 percentage points higher than the 51 percent that did use such methods," Agence France-Presse reports.

17 Jan 2010

Whitley urges public to get vaccinated against H1N1 influenza virus

With several months left in the influenza season and growing supplies of vaccine, now is an opportune time to get vaccinated against the 2009 H1N1 influenza virus, says Richard Whitley, M.D., director of the University of Alabama at Birmingham (UAB) Division of Pediatric Infectious Diseases and current president of the Infectious Diseases Society of America (IDSA).

13 Jan 2010

Studies suggest ways to prevent post-surgical infections in hospitals

Two new studies are suggesting relatively simple ways in which hospitals can prevent many post-surgical infections by killing bacteria the patients themselves bring in, according to Monday's New York Times.

13 Jan 2010

GAO: Some meds had 'extraordinary' price hikes over past eight years

A report from the Government Accountability Office (GAO) issued Monday finds that "[p]rices on a growing number of prescription medications have ballooned in recent years as consolidation in the drug industry leaves fewer companies manufacturing niche medications," The Associated Press reports.

12 Jan 2010

ViroPharma signs agreement with Sanquin Blood Supply Foundation to develop and commercialize Cinryze

ViroPharma Incorporated today announced that it has signed an agreement with Sanquin Blood Supply Foundation for rights to develop, file regulatory dossiers, and commercialize Cinryze(TM) (C1 esterase inhibitor [human]) for hereditary angioedema (HAE) as well as for potential new indications in certain European and rest of world (ROW) territories.

12 Jan 2010

Sorrento Therapeutics, Scripps Research Institute announce antibody development collaboration

Sorrento Therapeutics, Inc. today announced an antibody discovery and development collaboration with The Scripps Research Institute, La Jolla, CA. Under the terms of the agreement, Sorrento Therapeutics obtains an exclusive, worldwide license to the Institute's novel technology, based on quorum sensing, for the prevention and treatment of Staphylococcus aureus ('Staph') infections, including Methicillin-resistant Staph. aureus (MRSA).

12 Jan 2010

Cubist Pharmaceuticals reports total revenues for fourth-quarter and full-year 2009

Cubist Pharmaceuticals, Inc. today announced total revenues for both the fourth quarter and full year ended December 31, 2009.

11 Jan 2010

Galderma S.A. offers $3.75 million to NovaBay Pharmaceuticals

NovaBay Pharmaceuticals, Inc., a clinical stage biopharmaceutical company developing a new class of anti-infectives for treating multi-drug resistant pathogens, announced today that it has received $3.75 million in milestone payments from partner Galderma S.A.

11 Jan 2010

KaloBios Pharmaceuticals, Sanofi Pasteur partner in development of KB001 biologic for Pa infections

KaloBios Pharmaceuticals, Inc. today announced an agreement with Sanofi Pasteur, the vaccines division of the sanofi-aventis Group, for the development and commercialization of KB001, an investigational new biologic for the treatment or prevention of Pseudomonas aeruginosa (Pa) infections. Sanofi Pasteur will be responsible for the development and commercialization of KB001 and initially focus on hospital indications, including the prevention of Pa pneumonias in mechanically ventilated patients.

11 Jan 2010

Clinical Foundations' edition provides comprehensive review of hospital-acquired infections

Clinical Foundations, a patient-focused education program dedicated to helping respiratory care professionals stay current on clinical trends, has recently published a new edition titled “Pathogens Associated with the Intensive Care Unit Environment –Considerations for the Respiratory Therapist.”

9 Jan 2010

Frequent chlamydia screening does not reduce infection in teenage girls

Frequent testing and treatment of infection does not reduce the prevalence of chlamydia in urban teenage girls, according to a long term study by Indiana University School of Medicine researchers published in the January 1, 2010 issue of the Journal of Infectious Diseases.

8 Jan 2010

Oragenics declares equity private placement financing

On December 30, 2009, Oragenics, Inc. (the "Company") consummated a private placement of equity pursuant to a Common Stock Purchase Agreement (the "Agreement") with accredited investors.

6 Jan 2010

Opinions: U.S. medical emergency response; micronutrients; rotavirus vaccine; antibiotic development

"[D]espite the tireless efforts of public health and health-care workers, America's experience with H1N1 shows that the nation is not prepared to deal with a flu pandemic," former Democratic Senator Bob Graham and former Republican Senator Jim Talent write in Washington Post opinion piece that examines U.S. preparedness for medical emergencies. The writers chaired the Commission on the Prevention of Weapons of Mass Destruction Proliferation and Terrorism.

6 Jan 2010

Article about Enox Biopharma's self-sterilizing technology for catheters accepted for publication

A prestigious peer-review journal will publish an article in its January 2010 edition outlining a Vancouver BC based biomedical technology company's solution to the growing problem of hospital patients acquiring bacterial infections. The article about Enox Biopharma's self-sterilizing technology for catheters (patent pending) was accepted for publication in Antimicrobial Agents and Chemotherapy, a journal of the American Society for Microbiology and one of the most prominent publications in the field.

6 Jan 2010

Perturbing DISC1 gene could help researchers treat mental illness, says study

Scientists have long eyed mutations in a gene known as DISC1 as a possible contributor to schizophrenia and mood disorders, including depression and bipolar disorder. Now, new research led by Johns Hopkins researchers suggests that perturbing this gene during prenatal periods, postnatal periods or both may have different effects in mice, leading to separate types of brain alterations and behaviors with resemblance to schizophrenia or mood disorders.

6 Jan 2010

Swedish study opens new potential for combating resistant bacteria

Neisseria meningitidis, the meningococcus, is a bacterium that can cause diseases with high fatality rates, and there has therefore been considerable concern that, like other bacteria, it might become resistant to antibiotics. But now a study from örebro University and örebro University Hospital in Sweden shows that there has not been any increase in resistant meningococci in Sweden over the last 15 years. According to researcher Sara Thulin Hedberg, the reason for this may be that it is not especially advantageous for bacteria to develop resistance.

5 Jan 2010

Stop & Shop to hold H1N1 vaccination clinics at select pharmacies

The Stop & Shop Supermarket Company Giant today announced it will hold H1N1 vaccination clinics at select pharmacies starting January 8, 2010. Immunizations will cost $15 and be administered as long as quantities associated with this program are available.

5 Jan 2010

Research shows licorice root might be effective in fighting antibiotic-resistant infections

A team of scientists from the University of Texas Medical Branch and Shriners Hospitals for Children show how a compound from licorice root (glycyrrhizin from Glycyrrhiza glabra) might be an effective tool in battling life-threatening, antibiotic-resistant infections resulting from severe burns.

5 Jan 2010

Antibiotic News and Research

Further Reading

Enrollment of Phase 2 portion of Cempra Pharmaceuticals' Phase 2/3 clinical trial of TAKSTA completed

New insights into molecular interaction between probiotics and altered host intestinal ecosystem in IPAA

Also in Global Health News: Family planning in Philippines; drug pricing in Africa

Whitley urges public to get vaccinated against H1N1 influenza virus

Studies suggest ways to prevent post-surgical infections in hospitals

GAO: Some meds had 'extraordinary' price hikes over past eight years

ViroPharma signs agreement with Sanquin Blood Supply Foundation to develop and commercialize Cinryze

Sorrento Therapeutics, Scripps Research Institute announce antibody development collaboration

Cubist Pharmaceuticals reports total revenues for fourth-quarter and full-year 2009

Galderma S.A. offers $3.75 million to NovaBay Pharmaceuticals

KaloBios Pharmaceuticals, Sanofi Pasteur partner in development of KB001 biologic for Pa infections

Clinical Foundations' edition provides comprehensive review of hospital-acquired infections

Frequent chlamydia screening does not reduce infection in teenage girls

Oragenics declares equity private placement financing

Opinions: U.S. medical emergency response; micronutrients; rotavirus vaccine; antibiotic development

Article about Enox Biopharma's self-sterilizing technology for catheters accepted for publication

Perturbing DISC1 gene could help researchers treat mental illness, says study

Swedish study opens new potential for combating resistant bacteria

Stop & Shop to hold H1N1 vaccination clinics at select pharmacies

Research shows licorice root might be effective in fighting antibiotic-resistant infections

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Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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