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Positive interim data from Phase I/II trial of CYT387 in myelofibrosis presented at ASH Annual Meeting

YM BioSciences Inc. today announced positive interim data from the first 60 patients enrolled in the Phase I/II trial for its JAK1/JAK2 inhibitor, CYT387, in myelofibrosis. The results were reported today in an oral presentation at the 52nd American Society of Hematology Annual Meeting being held in Orlando, Florida.

7 Dec 2010

Alexion Pharmaceuticals reports interim results from phase 1 trial on samalizumab antibody

Alexion Pharmaceuticals, Inc. (Nasdaq: ALXN) today announced the presentation of interim results from the first Phase I/II trial of samalizumab, the company's investigational, first-in-class humanized monoclonal antibody.

6 Dec 2010

Study: REVLIMID and dexamethasone for high-risk smoldering multiple myeloma reduce risk of disease progression

Celgene International Sàrl (NASDAQ: CELG) announced that data evaluating combination therapy REVLIMID® (lenalidomide) and dexamethasone in patients with high-risk asymptomatic smoldering multiple myeloma were presented during the American Society of Hematology's annual meeting. The study reported REVLIMID and dexamethasone prolonged time to progression.

6 Dec 2010

Lundbeck reports positive phase III study data of clobazam in treating seizures associated with LGS

Today, Lundbeck Inc. presented positive data from its pivotal phase III study to determine the efficacy and safety profiles of the investigational compound clobazam as adjunctive therapy in treating seizures associated with Lennox-Gastaut syndrome.

6 Dec 2010

UIC scientist focuses on potential targets to inhibit malaria transmission

University of Illinois at Chicago researcher Dr. John Quigley will describe a promising new approach to blocking malaria transmission during the American Society of Hematology's annual meeting in Orlando, Fla.

6 Dec 2010

Health experts discuss how to prepare for future dengue immunization programs

AsiaOne examines how groups are working to prepare policy makers for the availability of a dengue vaccine in the future, following a three-day meeting on the virus held in Singapore this week (Chan, 12/3).

4 Dec 2010

MicroRNA linked to mosquito blood digestion and egg development identified

Each year, dengue fever infects as many as 100 million people while yellow fever is responsible for about 30,000 deaths worldwide. Both diseases are spread by infected female Aedes aegypti mosquitoes, which require vertebrate blood to produce eggs. The blood feeding and the egg development are tightly linked to how the mosquito transmits the disease-causing virus.

2 Dec 2010

More effective treatment for severe form of influenza

Flu season is upon us and while getting the nasty bug is bad news, the good news is it's now possible to treat the severe form of the virus more effectively, according to a Ryerson University researcher. Though Canada is not expecting a pandemic flu season this winter Health Canada reports that about 4,000 to 8,000 Canadians die each year from flu-related pneumonia.

2 Dec 2010

Physician-scientists enroll patients with NSCLC cancer in MAGE-A3 Phase III trial

An experimental immunotherapy may someday become the newest weapon against lung cancer. Physician-scientists from Weill Cornell Medical College and Columbia University Medical Center are enrolling patients with non-small cell lung cancer (NSCLC) at NewYork-Presbyterian Hospital as part of an ongoing Phase III trial.

1 Dec 2010

Canadians at increased risk for flu complications not aware of all the facts

It starts with a headache, chills or that all-over-achy feeling. It comes on quickly, yet too many Canadians ignore the rapid onset of flu symptoms. But for the millions of Canadians at increased risk for developing serious complications from the flu, including people 65 and older, pregnant women and those with chronic medical conditions like chronic obstructive pulmonary disease (COPD), asthma, heart disease and diabetes, this 'laissez faire' attitude could be putting their health in jeopardy.

30 Nov 2010

DTRA presents Outstanding Scientific Achievement award to Aduro BioTech

Aduro BioTech, a clinical-stage immunotherapy company, is pleased to announce the "Outstanding Scientific Achievement" award from the Defense Threat Reduction Agency. The award was presented at the 2010 Chemical and Biological Defense Science and Technology Conference in Orlando, Florida to Dr. Justin Skoble, Associate Director, Biodefense and Process Development at Aduro BioTech.

30 Nov 2010

NIAID scientists confirm antiviral activity of two lead compounds against HPV

Tamir Biotechnology, Inc. announced today that scientists supported by the National Institute of Allergy and Infectious Diseases (NIAID) reported test results confirming two of our lead compounds showed excellent in vitro antiviral activity and no cellular toxicity at dose levels tested for Human Papillomavirus (HPV).

30 Nov 2010

Overexposure to triclosan may negatively influence immune system: Study

Young people who are overexposed to antibacterial soaps containing triclosan may suffer more allergies, and exposure to higher levels of Bisphenol A among adults may negatively influence the immune system, a new University of Michigan School of Public Health study suggests.

29 Nov 2010

Superantigens can disrupt immune system, can cause more illnesses

Superantigens, the toxins produced by staphylococcus bacteria, are more complex than previously believed, reveals a team of researchers from the University of Gothenburg in an article published today in the scientific journal Nature Communications. Their discovery shows that the body's immune system can cause more illnesses than realised.

29 Nov 2010

Whooping cough outbreak in Oklahoma

Oklahoma is witnessing an outbreak of whooping cough with more people falling ill. Health authorities are urging all people over 7 years of age to get vaccinated against the disease.

28 Nov 2010

Paracetamol linked to childhood asthma: study

New Zealand researchers have found that young kids given fever medicine Paracetamol are twice as likely to develop asthma. The study is an observational one by the University of Otago Wellington researchers where the team looked at Paracetamol use in 505 infants and 914 five and six-year-olds.

28 Nov 2010

Pollen burst leads to 10 year spike in asthma cases

Melbourne hospitals are flooded with patients with respiratory problems in a phenomenon experts have described as “thunderstorm asthma”.

25 Nov 2010

Opinions: The Pope and condoms; fighting HIV/AIDS in South Africa; malaria eradication or control; health care workers; foreign aid in Haiti

Reflecting on Pope Benedict XVI's recent statements regarding the use of condoms to prevent the transmission of HIV, Michael Gerson writes in a Washington Post column.

24 Nov 2010

Study examines nosocomial outbreak of influenza in Hong Kong hospitals

Direct contact and droplets are the primary ways influenza spreads. Under certain conditions, however, aerosol transmission is possible. In a study published in the current issue of Clinical Infectious Diseases, available online, the authors examined such an outbreak in their own hospital in Hong Kong.

23 Nov 2010

Pennsylvania's first reported flu-related death of 2010-11 flu season

The Department of Health today confirmed a 45-year-old man from Lehigh County as Pennsylvania's first reported flu-related death of the 2010-11 flu season.

23 Nov 2010