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Study on current insect repellants confirms need for better insect repellants

Fire up the citronella-scented tiki torches, and slather on the DEET: Everybody knows these simple precautions repel insects, notably mosquitoes, whose bites not only itch and irritate, but also transmit diseases such as West Nile virus, malaria and dengue. Now, Johns Hopkins scientists have discovered what it is in the bugs' molecular makeup that enables citronellal (the aromatic liquid used in lotions, sprays and candles) and DEET, to deter insects from landing and feeding on you. A better understanding of these molecular-behavioral links already is aiding the team's search for more effective repellants.

26 Aug 2010

Ataxin 2 gene mutation contributes to Lou Gehrig's disease: Research

An international study led by biologists and neuroscientists from the University of Pennsylvania has identified a new genetic risk factor for amyotrophic lateral sclerosis, commonly known as ALS or Lou Gehrig's disease.

26 Aug 2010

Research finds adenovirus impact on cell's suicide program pave way for new cancer therapy

A novel mechanism used by adenovirus to sidestep the cell's suicide program, could go a long way to explain how tumor suppressor genes are silenced in tumor cells and pave the way for a new type of targeted cancer therapy, report researchers at the Salk Institute for Biological Studies in the Aug. 26, 2010 issue of Nature.

26 Aug 2010

Researchers prove iPS cells can help to treat liver diseases

Great excitement greeted the discovery a few years ago that certain cells from mice and humans could be reprogrammed to become inducible pluripotent stem cells (iPS cells), as they hold promise for cell replacement therapy and modeling human disease.

26 Aug 2010

ACT comments on federal fund blocking for embryonic stem cell research

Advanced Cell Technology, Inc. commented today on yesterday's federal court ruling, temporarily blocking federal funding for embryonic stem cell research involving the destruction of embryos.

26 Aug 2010

Today's Opinions: Applying comparative effectiveness research to a range of health indicators; Australia's model health care system; What about blocked stem cell research?

Significant comparative effectiveness research (CER) efforts should be dedicated to understanding the effectiveness of investments across broad determinants of health instead of focusing primarily within the health care domain alone (David Kindig and John Mullahy, 8/25).

26 Aug 2010

NeoStem responds to court ruling blocking government funding for embryonic stem cell research

NeoStem, Inc., an international biopharmaceutical company with operations in the U.S. and China, commented today on the ruling this week of a U.S. District Court blocking the federal government from funding research involving human embryonic stem cells. In issuing a preliminary injunction, the judge said it violated a law first passed in 1996 prohibiting federal money for research where a human embryo is destroyed.

25 Aug 2010

Stem cell therapy cures 12-year-old boy with diabetes

Cellonis Biotechnologies, a Beijing and HK-based medical research and application company, has recorded some remarkable results in the treatment of a twelve-year-old boy with diabetes using their stem cell therapy in a Beijing partner hospital. He has completely regained his normal life, enjoying sports and school activities just like every other person his age, and has been free from injections and drugs for more than half a year.

25 Aug 2010

Continuous boosting of natural painkiller shuts down brain cell receptor response

ERepeatedly boosting brain levels of one natural painkiller soon shuts down the brain cell receptors that respond to it, so that the painkilling effect is lost, according to a surprising new study led by Scripps Research Institute and Virginia Commonwealth University scientists. The study has important implications for drug development.

25 Aug 2010

Bisphenol A chemical may shorten reproductive lifespan in women: Research

A study posted today (Wednesday, August 25) at the online site of the journal Biology of Reproduction reports that exposure of pregnant female mice to the endocrine-disrupting chemical bisphenol A may produce adverse reproductive consequences on gene expression in fetal ovaries as early as 12 hours after the mother has first been exposed to the chemical.

25 Aug 2010

Human umbilical cord blood cells appear to protect astrocytes from cell death: Research

Human umbilical cord blood cells (HUCB) used to treat cultured rat brain cells (astrocytes) deprived of oxygen appear to protect astrocytes from cell death after stroke-like damage, reports a team of researchers from the University of South Florida (USF) Department of Neurosurgery and Brain Repair.

25 Aug 2010

First Edition: August 25, 2010

In today's headlines, news about a Medicare change that may cause an estimated three million seniors to switch their drug coverage.

25 Aug 2010

ZymoGenetics completes enrollment in Phase 2b PEG-IFN lambda clinical trial

ZymoGenetics, Inc. today announced enrollment has been completed in the Phase 2b clinical trial with PEG-Interferon lambda and ribavirin in chronic hepatitis C virus (HCV) infection.

25 Aug 2010

Vitamin D2 in AbM mushroom can neutralize oxidative stress: Research

Total Nutraceutical Solutions, Inc., announced that it has completed a research study comparing the therapeutic effect of single nutrient forms of synthetic Vitamin D3 and D2 versus natural Vitamin D2 within a whole food. The study focused on the control of Paraquat induced oxidative stress/biologic death.

25 Aug 2010

Study identifies four genetic variants associated with ESRD disease in Chinese diabetic patients

Examination of a gene involved in cell signaling finds that four common variants of this gene are associated with the development of end-stage renal disease in Chinese patients with type 2 diabetes, according to a study in the August 25 issue of JAMA.

25 Aug 2010

Cedarlane to distribute Pfenex's high value reagent proteins in Canada, U.S.

Pfenex Inc. and Cedarlane today announced that they have entered into a non-exclusive distribution agreement. Cedarlane will market and distribute high value reagent proteins produced by Pfenex to researchers in Canada and the United States.

25 Aug 2010

BIO president comments on U.S. District Court injunction on embryonic stem cell research funds

Biotechnology Industry Organization (BIO) President and CEO Jim Greenwood issued the following statement today regarding the injunction issued yesterday by a U.S. District Court prohibiting the use of federal funds to support embryonic stem cell research.

25 Aug 2010

CMC Biologics completes new, disposable manufacturing facility at Seattle

CMC Biologics, a Contract Manufacturing Organization with manufacturing sites in Europe and the USA, today announced the completion of a new state-of-the-art disposable manufacturing facility at its Seattle, WA site. The addition comes as part of a staged major expansion plan, which will add significant production capacity to its existing facility to accommodate a growing demand for cGMP manufacture of biopharmaceuticals.

25 Aug 2010

Mayo researchers develop new laboratory cell lines to study anaplastic thyroid cancer

To their deep dismay, researchers at Mayo Clinic discovered several years ago that laboratory samples of anaplastic thyroid cancer (ATC) they were using to help them find new treatments for this lethal disease were probably some other kind of cancer. It quickly became evident that the situation in their lab was common throughout the world. Up to half of the cell lines that were supposed to originate from patients with this rare thyroid cancer were either colon or melanoma cancer.

25 Aug 2010

New TRIM5α-based treatments can knock out HIV in humans: Research

Using a $225,000 microscope, researchers have identified the key components of a protein called TRIM5α that destroys HIV in rhesus monkeys.The finding could lead to new TRIM5α-based treatments that would knock out HIV in humans, said senior researcher Edward M. Campbell, PhD, of Loyola University Health System.

25 Aug 2010

B Cell News and Research

Study on current insect repellants confirms need for better insect repellants

Ataxin 2 gene mutation contributes to Lou Gehrig's disease: Research

Research finds adenovirus impact on cell's suicide program pave way for new cancer therapy

Researchers prove iPS cells can help to treat liver diseases

ACT comments on federal fund blocking for embryonic stem cell research

Today's Opinions: Applying comparative effectiveness research to a range of health indicators; Australia's model health care system; What about blocked stem cell research?

NeoStem responds to court ruling blocking government funding for embryonic stem cell research

Stem cell therapy cures 12-year-old boy with diabetes

Continuous boosting of natural painkiller shuts down brain cell receptor response

Bisphenol A chemical may shorten reproductive lifespan in women: Research

Human umbilical cord blood cells appear to protect astrocytes from cell death: Research

First Edition: August 25, 2010

ZymoGenetics completes enrollment in Phase 2b PEG-IFN lambda clinical trial

Vitamin D2 in AbM mushroom can neutralize oxidative stress: Research

Study identifies four genetic variants associated with ESRD disease in Chinese diabetic patients

Cedarlane to distribute Pfenex's high value reagent proteins in Canada, U.S.

BIO president comments on U.S. District Court injunction on embryonic stem cell research funds

CMC Biologics completes new, disposable manufacturing facility at Seattle

Mayo researchers develop new laboratory cell lines to study anaplastic thyroid cancer

New TRIM5α-based treatments can knock out HIV in humans: Research

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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