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Bioengineers and physician-scientists zap tumors with light-activated nanoparticles

Rice University bioengineers and physician-scientists at Baylor College of Medicine and Texas Children's Hospital have successfully destroyed tumors of human brain cancer cells in the first animal tests of a minimally invasive treatment that zaps glioma tumors with heat. The tests involved nanoshells, light-activated nanoparticles that are designed to destroy tumors with heat and avoid the unwanted side effects of drug and radiation therapies.

2 Feb 2011

Scientists discover breast cancer cells that dodge immune system, promote tumor growth

Scientists discovered a new way breast cancer cells dodge the immune system and promote tumor growth, providing a fresh treatment target in the fight against the disease. While comparable mechanisms to avoid the immune system have been identified in mice with breast and other cancers, the study tested human breast tumor cells, putting researchers closer to understanding how the disease progresses in real patients.

2 Feb 2011

Scientists test new dry powder measles vaccine that can be inhaled

Sustained high vaccination coverage is key to preventing deaths from measles. Despite the availability of a vaccine, measles remains an important killer of children worldwide, particularly in less-developed regions where vaccination coverage is limited. A team of researchers, led by scientists at the Johns Hopkins Bloomberg School of Public Health and the University of Colorado, developed and successfully tested a dry powder, live-attenuated measles vaccine that can be inhaled.

2 Feb 2011

New compound appears to prevent pain crises in sickle cell disease: GHSU

A new compound appears to prevent the traffic jam of cells that causes debilitating pain crises and associated mortality in sickle cell disease, Georgia Health Sciences University researchers report.

1 Feb 2011

AVEO commences enrollment in tivozanib Phase 2 study in renal cell carcinoma

AVEO Pharmaceuticals, Inc. today announced that it has initiated patient enrollment in a multi-center Phase 2 exploratory biomarker study of tivozanib, its lead product candidate designed to optimally block the VEGF pathway by inhibiting all three VEGF receptors, in patients with renal cell carcinoma (RCC).

1 Feb 2011

Prime Healthcare Services alleges extortion campaign by SEIU

Prime Healthcare Services (PHS), the largest for-profit hospital system in California and the only for-profit system among Thomson Reuters' Top 10 Health Systems in 2009, announced today that it has been the victim of an extortion campaign by the Service Employees International Union – United Healthcare Workers West (SEIU) over the past year.

1 Feb 2011

PhRMA: 299 medicines under development for prevention and treatment of heart disease and stroke

An American dies of heart disease every 39 seconds, and African Americans suffer a higher death rate from heart disease and stroke than Americans overall. Partly as a result of having the highest prevalence of high blood pressure in the world, African Americans have a 1.5 times greater rate of heart disease death than other Americans and a 1.8 times greater rate of fatal stroke.

1 Feb 2011

Researchers grow arteries with elasticity of natural blood vessels outside the body

University of Pittsburgh researchers have grown arteries that exhibit the elasticity of natural blood vessels at the highest levels reported, a development that could overcome a major barrier to creating living-tissue replacements for damaged arteries, the team reports in the Proceedings of the National Academy of Sciences.

1 Feb 2011

Red wine polyphenols prevent ageing-induced endothelial dysfunction

The endothelium is the inner lining of our blood vessels and normal functions of endothelial cells include enabling coagulation, platelet adhesion and immune function. Endothelial dysfunction is associated with reduced anticoagulant properties and the inability of arteries and arterioles to dilate fully.

1 Feb 2011

Researchers discover 'common set of dysregulated miRNAs in murine lupus models'

Potentially impacting future diagnosis and treatment of lupus, an immune illness affecting more than 5 million people worldwide, researchers at the Virginia-Maryland Regional College of Veterinary Medicine at Virginia Tech have likely uncovered where the breakdown in the body's lymphocyte molecular regulatory machinery is occurring.

1 Feb 2011

FDA approves 'Cornell Dots' for first clinical trial in humans to diagnose cancer

"Cornell Dots" - brightly glowing nanoparticles - may soon be used to light up cancer cells to aid in diagnosing and treating cancer. The U.S. Food and Drug Administration has approved the first clinical trial in humans of the new technology.

1 Feb 2011

Novel personalized therapy could treat metastatic melanoma and metastatic synovial cell sarcoma

Researchers have found that a novel form of personalized therapy that genetically engineers a patient's own anti-tumor immune cells to fight tumors could treat metastatic melanoma and metastatic synovial cell sarcoma, representing a potentially new therapeutic approach against these and other cancers.

1 Feb 2011

Loyola opens Comprehensive Diabetes Care Clinic in Hickory Hills

Untreated or poorly managed diabetes can cause severe health complications such as kidney failure, blindness, heart disease, stroke and nerve damage. To help diabetic patients more easily care for their condition, Loyola has opened the Comprehensive Diabetes Care Clinic at Loyola Center for Health at Hickory Hills.

1 Feb 2011

Widespread screening or ultrasound for blocked neck arteries not necessary to determine stroke risk

Widespread screening or routine ultrasound for blocked neck arteries to determine stroke risk isn't necessary, according to new guidelines from the American Heart Association/American Stroke Association, American College of Cardiology and other groups.

1 Feb 2011

Yale University scientists synthesize lomaiviticin that appears to destroy cancer stem cells

A team of Yale University scientists has synthesized for the first time a chemical compound called lomaiviticin aglycon, leading to the development of a new class of molecules that appear to target and destroy cancer stem cells.

1 Feb 2011

Johns Hopkins-led safety checklist program appears to reduce hospital deaths by 10%

A Johns Hopkins-led safety checklist program that virtually eliminated bloodstream infections in hospital intensive-care units throughout Michigan appears to have also reduced deaths by 10 percent, a new study suggests.

1 Feb 2011

Scientists devise safer way to create iPS cells

Researchers at Johns Hopkins have found a better way to create induced pluripotent stem (iPS) cells-adult cells reprogrammed with the properties of embryonic stem cells-from a small blood sample. This new method, described last week in Cell Research, avoids creating DNA changes that could lead to tumor formation.

1 Feb 2011

Walk briskly to boost memory

Researchers have found that older adults who took a brisk walk three times a week did better on memory tests and increased the size of their hippocampus, a portion of the brain involved with memory formation.

1 Feb 2011

“Enjoy your food but eat less”: Latest Dietary guidelines

New federal dietary guidelines, released Monday by the U.S. Department of Agriculture and the Department of Health and Human Services lays down some new rules in healthy eating that include consuming less empty calories, less salt and at least half a plate full of fruits and vegetables a day.

1 Feb 2011

French guy says Parkinson’s drug induced gambling and gay sex addiction, tries to sue GSK for $610,000

GlaxoSmithKline is being sued this week by a French father-of-two, alleging the British pharmaceutical firm’s drug – Reqip (Ropirnirole) to treat Parkinson’s disease turned him into a gay sex and gambling addict. Parkinson’s disease is a seriously and progressively debilitating disease that leads to tremors, slowing of movements and ultimately total immobility.

1 Feb 2011

Blood News and Research

Bioengineers and physician-scientists zap tumors with light-activated nanoparticles

Scientists discover breast cancer cells that dodge immune system, promote tumor growth

Scientists test new dry powder measles vaccine that can be inhaled

New compound appears to prevent pain crises in sickle cell disease: GHSU

AVEO commences enrollment in tivozanib Phase 2 study in renal cell carcinoma

Prime Healthcare Services alleges extortion campaign by SEIU

PhRMA: 299 medicines under development for prevention and treatment of heart disease and stroke

Researchers grow arteries with elasticity of natural blood vessels outside the body

Red wine polyphenols prevent ageing-induced endothelial dysfunction

Researchers discover 'common set of dysregulated miRNAs in murine lupus models'

FDA approves 'Cornell Dots' for first clinical trial in humans to diagnose cancer

Novel personalized therapy could treat metastatic melanoma and metastatic synovial cell sarcoma

Loyola opens Comprehensive Diabetes Care Clinic in Hickory Hills

Widespread screening or ultrasound for blocked neck arteries not necessary to determine stroke risk

Yale University scientists synthesize lomaiviticin that appears to destroy cancer stem cells

Johns Hopkins-led safety checklist program appears to reduce hospital deaths by 10%

Scientists devise safer way to create iPS cells

Walk briskly to boost memory

“Enjoy your food but eat less”: Latest Dietary guidelines

French guy says Parkinson’s drug induced gambling and gay sex addiction, tries to sue GSK for $610,000

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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