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Resistance to CD19 CAR T-cell therapy can be caused by CD19 splicing alterations

Resistance to CD19 CAR T-cell therapy, a type of immunotherapy that yields long-lasting remissions in many patients with B-cell leukemia, can be caused by CD19 splicing alterations, leading to loss of certain parts of the CD19 protein that are recognized by the CAR T cells.

31 Oct 2015

Scientists look through evolutionary lens to gain clearer picture of health, disease

To gain a clearer picture of health and disease, scientists have now provided an independent reference for all human variation by looking through the evolutionary lens of our nearest relatives.

31 Oct 2015

New practice guidelines for compulsory treatment of mentally ill patients

In psychiatric wards, patients used to be medicated indiscriminately against their will for decades if doctors thought it necessary. It was only after a Federal Constitution Court ruling a few years ago that patient autonomy has been strengthened.

31 Oct 2015

Saint Louis University ophthalmologist offers tips to manage night vision issues

Owls and cats are at an advantage as the days get darker, but humans may notice their vision takes a hit during their evening commute home as daylight hours shrink.

31 Oct 2015

UofL evaluates safety of new therapeutic vaccine in women with HPV 16, 18 infections

Cervical cancer is the fourth most frequently occurring cancer in women. Human papillomavirus (HPV) is present in 99 percent of cervical cancers and is considered to be their cause. While most HPV infections will clear naturally within a few years, there has been no treatment available to hasten or improve the chance of natural eradication.

31 Oct 2015

Penn Medicine's Gordon Baltuch performs 1,000th deep brain stimulation procedure

Deep brain stimulation (DBS) improves many of the motor symptoms of Parkinson's disease (PD) and is a life-alerting surgery for many patients. Penn Medicine's Gordon Baltuch, MD, a professor of Neurosurgery and director of the Penn Center for Functional and Restorative Neurosurgery, is one of the most prolific DBS surgeons in the world, having recently performed his 1,000th procedure, marking an important milestone for Baltuch and Penn Medicine.

31 Oct 2015

New campaign raises awareness of City of Hope's life-saving mission and impact

Imagine being diagnosed with one of the most rare and aggressive forms of breast cancer, given a five percent chance to live and told having children will never be an option. Southern California local Kommah McDowell was told just that— and then she went to City of Hope.

31 Oct 2015

GUMC study examines patients' most preferred methods for receiving common medical test results

The results of common medical tests are sometimes delivered to patients by email, letters or voice mail, but are these the most preferred methods? According to one of the first studies to look at this question, the answer is no.

31 Oct 2015

Coating implants with tissue plasminogen activator can prevent biofilm-related infections

Biofilms--mats of bacteria similar to the plaque that grows on teeth--frequently coat the surfaces of catheters, and of various medical implants and prostheses, where they can threaten lives or lead to failure of the implants. Antibiotics are impotent against biofilms.

31 Oct 2015

Prkci gene maintains balance in stem cell production

When it comes to stem cells, too much of a good thing isn't wonderful: producing too many new stem cells may lead to cancer; producing too few inhibits the repair and maintenance of the body.

31 Oct 2015

Blocking calcium-signaling pathway could inhibit Ebola virus and other sources of deadly infections

The Ebola virus acts fast. The course of infection, from exposure to recovery, or death, can take as little as two weeks. That may not leave enough time for the immune system to mount an effective response.

31 Oct 2015

Cologuard stool DNA test: An accurate screening option for Alaska Native people with colorectal cancer

Cologuard stool DNA testing for colorectal cancer was found to be an accurate noninvasive screening option for Alaska Native people, a population with one of world's highest rates of colorectal cancer, concluded researchers from the Alaska Native Tribal Health Consortium and Mayo Clinic.

31 Oct 2015

New anti-malarial ‘biobricks' could pave way for easier, cost-effective production of artemisinin drug

Students from Trinity College Dublin have successfully created anti-malarial ‘biobricks', which could pave the way for easier and more cost-effective production of the key drug artemisinin.

31 Oct 2015

Johns Hopkins doctors urge people to get vaccinated against influenza virus

Flu season is upon us again — and yes, you should get the flu vaccine. Doctors at the Johns Hopkins University School of Medicine say everyone 6 months of age and older should get vaccinated against the influenza virus this year.

31 Oct 2015

Interrupted sleep affects people's positive moods

A study led by Johns Hopkins Medicine researchers suggests that awakening several times throughout the night is more detrimental to people's positive moods than getting the same shortened amount of sleep without interruption.

31 Oct 2015

Stem cell transplantation may offer viable treatment for Alzheimer's disease patients

Alzheimer's disease (AD), affecting millions worldwide, is the leading cause of dementia. The prevalence of AD is rapidly increasing, and will possibly affect over 100 million people by 2050, yet there are no effective therapies for the disease.

31 Oct 2015

NABP report highlights significance of international collaboration in fight against illegal online drug sellers

Today, the National Association of Boards of Pharmacy issued a report discussing the importance of international collaboration in the fight against illegal online drug sellers. As detailed in the Internet Drug Outlet Identification Program Progress Report for State and Federal Regulators: October 2015, there is widespread agreement among multiple countries that Internet sales of medicinal products pose a health risk to their citizens.

31 Oct 2015

Physicians leave severe acne patients on ineffective antibiotics for too long before prescribing more potent drug

A medical records analysis by researchers at NYU Langone Medical Center concludes that physicians who treat severe acne leave too many patients on ineffective antibiotics for far too long before prescribing more potent needed therapy with the medication isotretinoin, sometimes known by its former brand name Accutane.

30 Oct 2015

Fast food TV ads pose threat to childrens' health

Fast food companies advertise children's meals on TV with ads that feature toy premiums, and it has been suggested that the use of these toy premiums may prompt children to request eating at fast food restaurants. In a new study scheduled for publication in The Journal of Pediatrics, researchers found that the more children watched television channels that aired ads for children's fast food meals, the more frequently their families visited those fast food restaurants.

30 Oct 2015

Mayo Clinic cancer experts find gaps in current colorectal cancer screening approaches

Colorectal cancer remains the second leading cause of cancer death for men and women combined in the U.S. The goal of screening is to reduce the number of people who die from this common cancer. According to Mayo Clinic cancer experts there are gaps in current screening approaches in terms of detection accuracy, patient willingness to use them, and accessibility.

30 Oct 2015

Medicine News and Research

Resistance to CD19 CAR T-cell therapy can be caused by CD19 splicing alterations

Scientists look through evolutionary lens to gain clearer picture of health, disease

New practice guidelines for compulsory treatment of mentally ill patients

Saint Louis University ophthalmologist offers tips to manage night vision issues

UofL evaluates safety of new therapeutic vaccine in women with HPV 16, 18 infections

Penn Medicine's Gordon Baltuch performs 1,000th deep brain stimulation procedure

New campaign raises awareness of City of Hope's life-saving mission and impact

GUMC study examines patients' most preferred methods for receiving common medical test results

Coating implants with tissue plasminogen activator can prevent biofilm-related infections

Prkci gene maintains balance in stem cell production

Blocking calcium-signaling pathway could inhibit Ebola virus and other sources of deadly infections

Cologuard stool DNA test: An accurate screening option for Alaska Native people with colorectal cancer

New anti-malarial ‘biobricks' could pave way for easier, cost-effective production of artemisinin drug

Johns Hopkins doctors urge people to get vaccinated against influenza virus

Interrupted sleep affects people's positive moods

Stem cell transplantation may offer viable treatment for Alzheimer's disease patients

NABP report highlights significance of international collaboration in fight against illegal online drug sellers

Physicians leave severe acne patients on ineffective antibiotics for too long before prescribing more potent drug

Fast food TV ads pose threat to childrens' health

Mayo Clinic cancer experts find gaps in current colorectal cancer screening approaches

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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