Laboratory News and Research

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Researchers compare the action of natural and therapeutic opioids

The human body naturally produces opioid-like substances, such as endorphins, which block the perception of pain and increase the feeling of well-being.

19 Apr 2023

Study finds increased prevalence of hypertension among people with severe obesity and a genetic variant

Obesity and its associated cardiometabolic issues are a major health concern in the U.S. and internationally.

19 Apr 2023

GW one of 18 clinical trial sites across the United States testing monkeypox vaccine in adolescents

The National Institutes of Health trial to evaluate the mpox (previously known as monkeypox) vaccine JYNNEOS has now entered the next stage and is studying the immune responses to and the safety of the vaccine in adolescents.

19 Apr 2023

Early pregnancy blood serum metabolomic profile reveals risk of developing diabetes

Researchers from the University of Turku discovered that women who developed prediabetes after pregnancy had aberrations already in their early pregnancy blood serum metabolomic profile.

19 Apr 2023

Cocktail of IgG3 antibodies could have a potent clinical effect against SARS-CoV-2

Is it possible to improve the antibodies that the body produces to fight SARS-CoV2? In a study led by researchers from Lund University in Sweden, this was investigated by redesigning antibodies and combining them against the virus.

18 Apr 2023

Precise genome editing approach can correct mutation that causes sickle cell disease

Scientists at St. Jude Children’s Research Hospital and the Broad Institute of MIT and Harvard showed how prime editing can correct the mutation that causes sickle cell disease in a potentially curative approach.

18 Apr 2023

Novel assay based on hybrid DNA-RNA probe for detecting food contaminated with salmonella

A team of researchers have developed an easy-to-use colorimetric assay for the detection of food contaminated with salmonella.

18 Apr 2023

Beckman Coulter Life Sciences achieves industry-first reagent certification to help prepare labs for IVDR and to clear confusion

Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, is leading the way to help laboratories prepare for critical upgrades to comply with the new In Vitro Diagnostic Medical Devices Regulation (IVDR), and to clear up confusion for laboratories that will soon be governed by IVDR.

From Beckman Coulter Life Sciences 18 Apr 2023

Did COVID-19-associated lockdowns increase the rate of memory decline in patients with cognitive impairments?

Researchers investigated whether COVID-19-associated lockdown measures had an impact on the cognitive decline rate.

18 Apr 2023

Tissue-resident memory cells are key to immunity to Salmonella in mice

Salmonella infections cause about a million deaths a year worldwide, and there is an urgent need for better vaccines for both typhoid fever and non-typhoidal Salmonella disease.

18 Apr 2023

Scientists discover a protein domain that could lead to new COVID-19 treatments

Oak Ridge National Laboratory scientists exploring bioenergy plant genetics have made a surprising discovery: a protein domain that could lead to new COVID-19 treatments.

18 Apr 2023

New AI-based method for virtual staining of histopathological tissue samples

Researchers from the University of Eastern Finland, the University of Turku, and Tampere University have developed an artificial intelligence-based method for virtual staining of histopathological tissue samples as a part of the Nordic ABCAP consortium. Chemical staining has been the cornerstone of studying histopathology for more than a century and is widely applied in, for example, cancer diagnostics.

18 Apr 2023

Metagenomic sequencing offers rapid, accurate diagnosis of antimicrobial resistance in bloodstream infections

Metagenomic sequencing can provide rapid and actionable antimicrobial resistance predictions to treat bloodstream infections much faster than conventional laboratory tests, and has the potential to save lives and better manage the use of antibiotics, according to new research being presented at this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Copenhagen, Denmark (15-18 April).

17 Apr 2023

Study offers novel insights into reducing adverse effects of antibiotics on the gut microbiome

Antibiotics help to fight bacterial infections, but they can also harm the helpful microbes living in the gut, which can have long-lasting health consequences.

17 Apr 2023

Global novel disease surveillance: Majority of countries lack preparednes

Researchers explored national surveillance for new diseases in different countries.

15 Apr 2023

Monovalent and bivalent COVID boosters provide strong protection against severe outcomes in older adults

Researchers examined the effectiveness of SARS-CoV-2 booster doses in preventing severe Omicron infection outcomes.

15 Apr 2023

The neural mechanisms causing long-COVID fatigue

Researchers investigated the neural mechanisms underlying post-coronavirus disease fatigue.

14 Apr 2023

New clinical RNA sequencing platform helps carve a path for Precision Child Health

A new clinical RNA sequencing platform at The Hospital for Sick Children (SickKids) is helping to facilitate research into rare genetic conditions and carve a path for Precision Child Health, a movement at SickKids to deliver individualized care for every patient.

13 Apr 2023

Researchers develop new approach for studying HBV in the lab

Hepatitis C and hepatitis B viruses both attack the liver, eventually causing deadly cirrhosis or cancer. But while antivirals can cure 95 percent of HCV infections, its cousin HBV has long eluded effective therapeutics.

13 Apr 2023

AI-designed T-cell vaccine extremely effective at preventing severe COVID-19 in mice

The current COVID-19 vaccines are designed to trigger an antibody response to the SARS-CoV-2 spike protein, which is vulnerable to mutations that could make the vaccine less effective over time.

13 Apr 2023

Laboratory News and Research

Researchers compare the action of natural and therapeutic opioids

Study finds increased prevalence of hypertension among people with severe obesity and a genetic variant

GW one of 18 clinical trial sites across the United States testing monkeypox vaccine in adolescents

Early pregnancy blood serum metabolomic profile reveals risk of developing diabetes

Cocktail of IgG3 antibodies could have a potent clinical effect against SARS-CoV-2

Precise genome editing approach can correct mutation that causes sickle cell disease

Novel assay based on hybrid DNA-RNA probe for detecting food contaminated with salmonella

Beckman Coulter Life Sciences achieves industry-first reagent certification to help prepare labs for IVDR and to clear confusion

Did COVID-19-associated lockdowns increase the rate of memory decline in patients with cognitive impairments?

Tissue-resident memory cells are key to immunity to Salmonella in mice

Scientists discover a protein domain that could lead to new COVID-19 treatments

New AI-based method for virtual staining of histopathological tissue samples

Metagenomic sequencing offers rapid, accurate diagnosis of antimicrobial resistance in bloodstream infections

Study offers novel insights into reducing adverse effects of antibiotics on the gut microbiome

Global novel disease surveillance: Majority of countries lack preparednes

Monovalent and bivalent COVID boosters provide strong protection against severe outcomes in older adults

The neural mechanisms causing long-COVID fatigue

New clinical RNA sequencing platform helps carve a path for Precision Child Health

Researchers develop new approach for studying HBV in the lab

AI-designed T-cell vaccine extremely effective at preventing severe COVID-19 in mice

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