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Research findings could guide development of potent combination therapies for leukemia

New findings from Rockefeller University researchers could guide the development of potent combination therapies that deliver more effective and durable treatment of leukemia.

7 Mar 2017

New drug-like compound shows potential to treat symptoms of lupus

Lupus, a chronic autoimmune disease, has proved difficult to treat, but a new international study co-led by a Rush University Medical Center researcher suggests that a drug starting through the pipeline could ameliorate or even eliminate the symptoms in most sufferers.

7 Mar 2017

TSRI scientists discover how key protein establishes proper vision

Scientists from the Florida campus of The Scripps Research Institute have discovered how a protein called α2δ4 establishes proper vision.

6 Mar 2017

Michigan Medicine opens first clinic in the United States that focuses on prostate cancer risk

It's well known that women with certain hereditary genetic mutations, particularly BRCA1 and BRCA2, have an increased risk of breast cancer. But in recent years, researchers have discovered a link between some of those same genetic mutations - along with a handful of others - and aggressive prostate cancer.

3 Mar 2017

New software tool enables quick, easy deletion of DNA in living cells

Until recently, genomics was a "read-only" science, but scientists have developed a tool for quick and easy deletion of DNA in living cells.

3 Mar 2017

Scientists discover how misfolded proteins can damage cells’ energy-producing powerhouses

Working with yeast and human cells, researchers at Johns Hopkins say they have discovered an unexpected route for cells to eliminate protein clumps that may sometimes be the molecular equivalent of throwing too much or the wrong trash into the garbage disposal.

3 Mar 2017

Researchers discover 'Developmental Split-Brain syndrome' caused by biallelic mutations in DCC gene

In a study published in Nature Genetics, Dr Saumya Jamuar, co-founder of Global Gene Corp and a visiting scientist at Harvard Medical School, under the supervision of Prof Christopher Walsh and A/Prof Timothy Yu of Harvard Medical School, reports on a new disease entity that they discovered in their quest to map novel human disorders related to brain development.

3 Mar 2017

Rheumatoid arthritis drug blocks metabolic pathway, reduces breast cancer tumors in mice

Mount Sinai researchers have discovered that a rheumatoid arthritis drug can block a metabolic pathway that occurs in tumors with a common cancer-causing gene mutation, offering a new possible therapy for aggressive cancers with few therapeutic options, according to a study to be published in Cancer Discovery.

3 Mar 2017

Researchers develop smart genetic reference library for locating disease-causing mutations

Researchers at Hiroshima University have developed a smart genetic reference library for locating and weeding out disease-causing mutations in populations.

3 Mar 2017

Case Western Reserve and VA team up to tackle rising problem of antibiotic resistance

Since the discovery of penicillin in 1928, antibiotics have made the world a much safer and healthier place. But Shakespeare was onto something when he asked if it's possible to have too much of a good thing. In the case of antibiotics, the answer is increasingly "yes."

3 Mar 2017

Innovative gene therapy allows complete remission of clinical signs of sickle cell disease

A team led by Pr. Marina Cavazzana conducted at Necker Children's Hospital, AP-HP and the Imagine Institute in October 2014 gene therapy in the context of a phase I clinical trial / II in a patient 13 years with severe sickle cell disease.

2 Mar 2017

Red hair-related gene variant may contribute to link between melanoma and Parkinson's disease

A gene variant that produces red hair and fair skin in humans and in mice, which increases the risk of the dangerous skin cancer melanoma, may also contribute to the known association between melanoma and Parkinson's disease.

2 Mar 2017

Scientists use molecular bait strategy to capture and isolate cancer-prone protein

Scientists from the Center for Self-assembly and Complexity (CSC) successfully isolated a cancer-prone protein by fishing out the proteins using 'molecular bait'.

2 Mar 2017

Highly prevalent gene variants in African Americans contribute to kidney disease

African Americans have a heightened risk of developing chronic and end-stage kidney disease. This association has been attributed to two common genetic variants - named G1 and G2 -- in APOL1, a gene that codes for a human-specific protein.

1 Mar 2017

Two migration proteins increase predictive ability of biomarker for pancreatic cancer

Adding two blood-borne proteins associated with cancer cell migration increases the predictive ability of the current biomarker for pancreatic cancer to detect early stage disease, a research team from The University of Texas MD Anderson Cancer Center reports in the Journal of the National Cancer Institute.

1 Mar 2017

Mutation News and Research

Research findings could guide development of potent combination therapies for leukemia

New drug-like compound shows potential to treat symptoms of lupus

TSRI scientists discover how key protein establishes proper vision

Michigan Medicine opens first clinic in the United States that focuses on prostate cancer risk

New software tool enables quick, easy deletion of DNA in living cells

Scientists discover how misfolded proteins can damage cells’ energy-producing powerhouses

Researchers discover 'Developmental Split-Brain syndrome' caused by biallelic mutations in DCC gene

Rheumatoid arthritis drug blocks metabolic pathway, reduces breast cancer tumors in mice

Researchers develop smart genetic reference library for locating disease-causing mutations

Case Western Reserve and VA team up to tackle rising problem of antibiotic resistance

Innovative gene therapy allows complete remission of clinical signs of sickle cell disease

Red hair-related gene variant may contribute to link between melanoma and Parkinson's disease

Scientists use molecular bait strategy to capture and isolate cancer-prone protein

Highly prevalent gene variants in African Americans contribute to kidney disease

Two migration proteins increase predictive ability of biomarker for pancreatic cancer

Mayo Clinic researchers identify new genetic risk factor for late-onset Alzheimer's in African-Americans

Danish researchers get closer to finding treatment for malignant cerebral tumour in children

Biologists develop new way to inhibit cancer cell cleanup mechanism

KRAS ‘imbalances’ that emerge over time may influence cancer treatment response

Scientists discover how genetic mutation disarms tumor-suppressing BRCA1 proteins in breast cancer

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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