Immune Response News and Research

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Brief exposure to pollution-causing particles triggers lung infections in children

Even the briefest increase in airborne fine particulate matter PM2.5, pollution-causing particles that are about 3% of the diameter of human hair, is associated with the development of acute lower respiratory infection in young children, according to newly published research.

13 Apr 2018

Research reveals immune suppressive role of soluble antibodies in tumor progression

Wistar researchers have found that soluble antibodies promote tumor progression by inducing accumulation of myeloid-derived suppressor cells (MDSCs) in pre-clinical cancer models. Results were published online in Cancer Immunology Research.

13 Apr 2018

Researchers show how highly contagious norovirus infection starts in mice

Norovirus – the highly contagious gastrointestinal illness best known for spreading rapidly on cruise chips, in nursing homes, schools and other densely populated spaces – kills an estimated 200,000 people annually, mostly in the developing world.

12 Apr 2018

Researchers get one step closer to creating peptide vaccine against atherosclerosis

In the disease atherosclerosis, cholesterol-containing plaques form in vessel walls, causing arteries to narrow and greatly increasing the risk of heart attack and stroke.

12 Apr 2018

Researchers develop thin, flexible polymers to record activity more deeply in the brain

Science has yet to unravel a complete understanding of the brain and all its intricate workings. It's not for lack of effort.

11 Apr 2018

Ludwig scientists develop and test individualized ovarian cancer vaccine

A Ludwig Cancer Research study has shown that an entirely new type of personalized cancer vaccine induces novel, potent and clinically effective immune responses in patients receiving a combination of standard therapies for recurrent, stage III and IV ovarian cancer.

11 Apr 2018

New cancer vaccine yields promising results in clinical study

A new type of cancer vaccine has yielded promising results in an initial clinical trial conducted at the Perelman School of Medicine at the University of Pennsylvania and the Abramson Cancer Center of the University of Pennsylvania.

11 Apr 2018

Nasal vaccine may suppress peanut allergy in mice, study shows

A vaccine may successfully turn off peanut allergy in mice, a new study shows.Just three monthly doses of a nasal vaccine protected the mice from allergic reactions upon exposure to peanut, according to research from the Mary H. Weiser Food Allergy Center at the University of Michigan.

11 Apr 2018

Using the Microbiome to Predict the Risk of Cirrhosis-Associated Hospitalization

The microbiome is the collection of microorganisms that colonize the human body. Dr. Jasmohan Bajaj discusses the relationship between the microorganisms in the gut and cirrhosis, and how microbiome analysis can be used to predict the risk of cirrhosis-associated hospitalizations.

7 Apr 2018

Researchers identify macrophage populations involved in development of atherosclerosis

Stroke and heart attack are the leading cause of death in the Western world. Würzburg scientists have used a special technique to get a clearer picture of the cells involved and their activity.

5 Apr 2018

New point-of-care test accelerates diagnosis of Lyme neuroborreliosis

A new research-based point-of-care test has been developed in Finland for detecting the Lyme neuroborreliosis spread by ticks.

5 Apr 2018

Microscopic revelations could lead to new treatment options for deadly blood infections

Researchers at the University of Calgary's Cumming School of Medicine (CSM) have for the first time been able to observe -- live and in real-time -- how the human body responds to often lethal fungal blood infections in the lung.

4 Apr 2018

Researchers develop improved method for calculating type 1 diabetes risk

An international research group headed by scientists from Helmholtz Zentrum München has developed a method for calculating the risk for developing type 1 diabetes that is significantly superior to earlier methods.

4 Apr 2018

'Molecular scissors' could play pivotal role in fighting diseases including HIV infection

One way to fight diseases including HIV infection and autoimmune disorders could involve changing how a naturally occurring enzyme called SAMHD1 works to influence the immune system, new research suggests.

3 Apr 2018

Gut bacteria may hold clues to predict effectiveness of cancer immunotherapies

The composition of bacteria in the gastrointestinal tract may hold clues to help predict which cancer patients are most apt to benefit from the personalized cellular therapies that have shown unprecedented promise in the fight against hard-to-treat cancers, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

3 Apr 2018

Study uncovers mechanism causing chronic GVHD after bone marrow transplant

Allogeneic bone marrow transplant (BMT) is an essential treatment to cure patients with blood cancers such as leukemia. In patients who have undergone chemotherapy and radiation, a small number of cancer cells can remain in the bloodstream and allow the malignancy to recur.

3 Apr 2018

Combined treatment prolongs survival in mouse models of malignant mesothelioma

Combined treatment with two cancer immunotherapy drugs - one a novel immune modulator and one that focuses and activates the antitumor immune response - significantly prolonged survival in mouse models of the aggressive cancer malignant mesothelioma.

2 Apr 2018

Researchers create new compound that appears to activate cancer-fighting T cells

Invariant natural killer T (iNKT) cells are powerful weapons our body's immune systems count on to fight infection and combat diseases like cancer, multiple sclerosis, and lupus. Finding ways to spark these potent cells into action could lead to more effective cancer treatments and vaccines.

2 Apr 2018

Researchers unravel immunopathogenesis of Johne's disease

A research team has unraveled the immunopathogenesis of Johne's disease, a chronic bovine disease that has caused endemics in Japan and many other countries, placing financial burdens on cattle farmers.

2 Apr 2018

Research reveals role of colon signaling pathway in development of IBD

The intestine encounters more foreign substances, and potential toxins, than other parts of the body, so it is not surprising that a healthy gut is maintained by the tight control of immune responses.

30 Mar 2018

Immune Response News and Research

Brief exposure to pollution-causing particles triggers lung infections in children

Research reveals immune suppressive role of soluble antibodies in tumor progression

Researchers show how highly contagious norovirus infection starts in mice

Researchers get one step closer to creating peptide vaccine against atherosclerosis

Researchers develop thin, flexible polymers to record activity more deeply in the brain

Ludwig scientists develop and test individualized ovarian cancer vaccine

New cancer vaccine yields promising results in clinical study

Nasal vaccine may suppress peanut allergy in mice, study shows

Using the Microbiome to Predict the Risk of Cirrhosis-Associated Hospitalization

Researchers identify macrophage populations involved in development of atherosclerosis

New point-of-care test accelerates diagnosis of Lyme neuroborreliosis

Microscopic revelations could lead to new treatment options for deadly blood infections

Researchers develop improved method for calculating type 1 diabetes risk

'Molecular scissors' could play pivotal role in fighting diseases including HIV infection

Gut bacteria may hold clues to predict effectiveness of cancer immunotherapies

Study uncovers mechanism causing chronic GVHD after bone marrow transplant

Combined treatment prolongs survival in mouse models of malignant mesothelioma

Researchers create new compound that appears to activate cancer-fighting T cells

Researchers unravel immunopathogenesis of Johne's disease

Research reveals role of colon signaling pathway in development of IBD

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