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UMSOM researchers to test the safety, tolerability of prototype Shigella-ETEC vaccine

Each year, millions of people contract serious diarrheal illnesses typically from contaminated food and water. Among the biggest causes of diarrheal diseases are the bacteria Shigella and enterotoxigenic Escherichia coli, and researchers at the University of Maryland School of Medicine are testing a vaccine designed to offer protection against these serious pathogens.

10 Dec 2019

Study focuses on smoking cessation treatment for adolescents

Preventable deaths are those that can be stymied by public health intervention, and deaths related to tobacco use are at the top of that list in the United States as well as globally.

10 Dec 2019

Combination regimen shows promising results in preclinical models of triple negative breast cancer

Tumor volume in a preclinical model of triple negative breast cancer (TNBC) was reduced four times more when an experimental polo-like kinase 1 (PLK1) inhibitor was combined with a standard-of-care chemotherapeutic agent than when the agent was used alone.

10 Dec 2019

New free mobile app helps families keep their infants safe

Placing an infant to sleep safely can save lives. A new, free mobile app, Baby be Well, helps families keep their infants safe throughout the first year of life.

10 Dec 2019

Study finds irregular brain function in children with Type 1 diabetes

Children with Type 1 diabetes show subtle but important differences in brain function compared with those who don't have the disease, a study led by researchers at the Stanford University School of Medicine has shown.

10 Dec 2019

Study can help illuminate the ways stress and external events affect mental health

They work in a bubble of 80-hour work weeks, and 24-hour shifts. They're caring for patients for the first time, while still learning the ropes of the medical profession. The constant stress wears on their mental health.

10 Dec 2019

Rutgers researchers identify small mutations for AML and MDS through deep DNA sequencing

Deep DNA sequencing analysis conducted by Rutgers Cancer Institute of New Jersey investigators examining genomic differences within tumors for prediction of disease relapse in certain hematologic malignancies has identified small mutations.

9 Dec 2019

Retrospective review: Proton therapy well tolerated in patients undergoing breast conserving surgery

While the assessment of proton therapy in breast cancer treatment continues through clinical trials, data relating to early toxicity and cosmetic outcomes for this population are limited.

9 Dec 2019

Common antibiotic appears to boost the effect of radiation on tumor cells

The antibiotic vancomycin alters the gut microbiome in a way that can help prime the immune system to more effectively attack tumor cells after radiation therapy.

9 Dec 2019

'Achilles' heel' of deadly superbug identified

A deadly superbug that infects an estimated 54,500 Americans a year has a secret weapon, a protein, that allows it to defy antibiotic treatment and immune system attacks.

9 Dec 2019

Innovative experimental therapy may stop growth of triple-negative breast cancer

Mount Sinai researchers have designed an innovative experimental therapy that may be able to stop the growth of triple-negative breast cancer, the deadliest type of breast cancer, which has few effective treatment options, according to a study published in Nature Chemical Biology in December.

9 Dec 2019

Short-term exercise could help to reduce side-effects of prostate hormone therapy

A prescription of short-term exercise for patients with advanced prostate cancer could help to reduce the side-effects of hormone therapy, according to new research from the University of East Anglia.

9 Dec 2019

Important biomarker may help in determining prognosis of brain cancer patients

A common virus that is harmless to most individuals may produce an important biomarker in determining the prognosis of brain cancer patients, according to a recent study published by a student researcher at the University of Cincinnati.

9 Dec 2019

Facial injuries related to cell phones have risen steeply

National emergency room data analysis has shown that number of injuries related to cell phones has risen in the last 20 years.

9 Dec 2019

A patient's tolerance for risky decisions can predict chances of opioid relapse

People in treatment for opioid addiction are more likely to relapse when they become more tolerant of risks, according to a study by Rutgers and other institutions. The findings can help clinicians better predict which patients are most vulnerable.

8 Dec 2019

$Experimental immunotherapy can put patients with relapsed or refractory lymphoma into remission$

Experimental immunotherapy can put patients with relapsed or refractory lymphoma into remission

A new, experimental immunotherapy can put patients with B-cell non-Hodgkin lymphoma (NHL) that is resistant to or has come back after multiple other therapies, including CAR T therapy, into remission.

8 Dec 2019

UM Medicine launches new centers in Maryland to treat adults with neurodevelopmental disabilities

The University of Maryland School of Medicine, University of Maryland Medical Center, and the Tuberous Sclerosis Alliance have joined together to launch first-of-a-kind centers in Maryland to treat adults with neurodevelopmental disabilities, such as autism.

8 Dec 2019

New startup aims to prevent reperfusion-related organ damage after liver transplant

Roughly 65 years ago, the first human organ transplant was successfully performed. A decade later, heart and liver transplants became possible. Now, a startup founded by researchers from the Medical University of South Carolina and elsewhere hopes to bring about the next major breakthrough.

8 Dec 2019

New technique holds promise in cancer research and science studies

A new technique reported this week in Science overcomes several limitations of typical high-throughput chemical screens conducted on cell samples. Such screens are commonly used to try to discover new cancer drugs, and in many other biomedical applications.

8 Dec 2019

Genetically engineered living hydrogel material facilitates intestinal wound healing

About 1.6 million people in the US alone currently have lifelong and incurable Inflammatory Bowel Disease (IBD) including Crohn's disease and ulcerative colitis, and 70,000 new cases are diagnosed in the USA each year.

6 Dec 2019

Medical School News and Research

UMSOM researchers to test the safety, tolerability of prototype Shigella-ETEC vaccine

Study focuses on smoking cessation treatment for adolescents

Combination regimen shows promising results in preclinical models of triple negative breast cancer

New free mobile app helps families keep their infants safe

Study finds irregular brain function in children with Type 1 diabetes

Study can help illuminate the ways stress and external events affect mental health

Rutgers researchers identify small mutations for AML and MDS through deep DNA sequencing

Retrospective review: Proton therapy well tolerated in patients undergoing breast conserving surgery

Common antibiotic appears to boost the effect of radiation on tumor cells

'Achilles' heel' of deadly superbug identified

Innovative experimental therapy may stop growth of triple-negative breast cancer

Short-term exercise could help to reduce side-effects of prostate hormone therapy

Important biomarker may help in determining prognosis of brain cancer patients

Facial injuries related to cell phones have risen steeply

A patient's tolerance for risky decisions can predict chances of opioid relapse

Experimental immunotherapy can put patients with relapsed or refractory lymphoma into remission

UM Medicine launches new centers in Maryland to treat adults with neurodevelopmental disabilities

New startup aims to prevent reperfusion-related organ damage after liver transplant

New technique holds promise in cancer research and science studies

Genetically engineered living hydrogel material facilitates intestinal wound healing

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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