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EU, India leaders meet to discuss trade deal, some concerned deal will jeopardize drug access in developing countries

On Friday, Indian Commerce Minister Anand Sharma and EU Trade Commissioner Karel de Gucht met to "present a status report on the ongoing free trade talks" that some health advocates fear could limit the supply of generic medications in developing countries, according to Business Standard. "An EU source said the report would signal that talks had made excellent progress and should be wrapped up by early next year," according to the news service (Aiyar, 12/10).

13 Dec 2010

Researchers generate insulin-secreting pancreatic islet cells from human SSCs

Insulin-secreting pancreatic islet cells have been generated from human spermatogonial stem cells (SSCs) directly isolated from human testicular tissue, researchers reported today at the American Association of Cell Biology 50th Annual Meeting in Philadelphia.

13 Dec 2010

Stem cell therapy can reduce risk of acute leukemia in affected individuals

Some adults and children with acute leukemia could benefit from certain transplants of blood stem cells, but the benefits are not equal across all cases of leukemia, according to a new review of 15 studies.

13 Dec 2010

High CTC level found to be early marker of poor outcome in metastatic breast cancer

A high level of circulating tumor cells (CTCs) - cells that have detached from a tumor and are circulating in the body through the blood - are an independent prognostic marker in metastatic breast cancer as first-line therapy.

13 Dec 2010

Official guidelines for diagnosis, treatment and management of food allergies released

A collaborative, government-led effort to guide and standardize diagnosis, treatment and management of food allergies has resulted in the release of an official set of recommendations for physicians.

10 Dec 2010

Epigenetic-molecular targeted therapy combination holds promise against advanced lung cancer

A new study shows that a combination of epigenetic therapy and molecular targeted therapy has promising results at combating advanced lung cancer according to research presented at the 2010 Chicago Multidisciplinary Symposium in Thoracic Oncology. This symposium is co-sponsored by the American Society for Radiation Oncology (ASTRO), the American Society of Clinical Oncology (ASCO), the International Association for the Study of Lung Cancer (ISLAC) and The University of Chicago.

10 Dec 2010

Pisgah's technology imparts abuse deterrence to commonly abused prescription drugs

Pisgah Labs announced today the findings from a proof of concept study confirming Pisgah's technology imparts abuse deterrence to commonly abused prescription drugs, particularly narcotics. The controlled study, conducted in dogs, was performed with the un-formulated active ingredient, hydrocodone, as modified according to a host of patent applications filed by Pisgah Labs with the United States Patent and Trademark Office (http://www.uspto.gov).

10 Dec 2010

STENTYS initiates international APPOSITION III self-apposing stent study in AMI patients

STENTYS S.A., which develops innovative stents to treat Acute Myocardial Infarction (AMI), announced today that it has begun the international APPOSITION III study of its self-apposing stent, with 50 patients already enrolled out of a total of 500. The trial primary endpoint is Major Adverse Cardiac Events at 12 months post-procedure.

10 Dec 2010

Everolimus plus tamoxifen delays disease progression in HR+/HER2- metastatic breast cancer

A new study shows that the addition of everolimus (Afinitor® tablets) to the hormonal therapy tamoxifen in patients with hormone-receptor positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) metastatic breast cancer who have been previously treated with an aromatase inhibitor (AI) delays disease progression compared to tamoxifen alone. These results were presented today at the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium in San Antonio, Texas.

10 Dec 2010

First genetic test on developing risk of Alzheimer's disease and heart attacks

Alzheimer and heart attacks have been found to share common genetic basis. The research leads the way to the first genetic test on developing the risk of the diseases even at a young age. According to Federico Licastro, an immunologist at the University of Bologna who coordinated the study published in the scientific journal, Journal of Alzheimer's Disease, a test is now ready. "They are already selling it in America", he says, citing the case of a private firm in New Mexico (USA) that collaborated on the study. "But the tests could easily be also conducted wherever, using a simple blood test".

10 Dec 2010

Fibrin microthreads support mesenchymal stem cell growth

A research team at Worcester Polytechnic Institute has demonstrated the feasibility of a novel technology that a surgeon could use to deliver stem cells to targeted areas of the body to repair diseased or damaged tissue, including cardiac muscle damaged by a heart attack. The technique involves bundling biopolymer microthreads into biological sutures and seeding the sutures with stem cells. The team has shown that the adult bone-marrow-derived stem cells will multiply while attached to the threads and retain their ability to differentiate and grow into other cell types.

10 Dec 2010

Blocking growth of blood vessels with antibodies could improve treatment of cancerous tumors

A novel strategy of blocking the growth of blood vessels with antibodies should result in improved treatment of cancerous tumors.

10 Dec 2010

New 5-minute Memory Orientation Screening Test to identify elderly patients with dementia

A new 5-minute test to identify elderly patients with dementia promises to give doctors a more sensitive tool to use in the Annual Wellness Examination. The Memory Orientation Screening Test (MOST™) developed by Mitchell Clionsky, Ph.D., a neuropsychologist, and Emilymarie Clionsky, MD, an internist/psychiatrist, is based on their clinical experience with thousands of patients who suffer from Alzheimer's Disease and other dementias, which now afflicts more than 5 million Americans.

10 Dec 2010

Using buprenorphine to treat opioid-dependent pregnant women may result in healthier babies

Using buprenorphine instead of methadone — the current standard of care — to treat opioid-dependent pregnant women may result in healthier babies, suggests new findings from an international team led by Johns Hopkins researchers and published in the Dec. 9 issue of the New England Journal of Medicine.

10 Dec 2010

Exposure to tobacco smoke causes immediate damage leading to serious illness or death

Exposure to tobacco smoke - even occasional smoking or secondhand smoke - causes immediate damage to your body that can lead to serious illness or death, according to a report released today by U.S. Surgeon General Regina M. Benjamin. The comprehensive scientific report - Benjamin's first Surgeon General's report and the 30th tobacco-related Surgeon General's report issued since 1964 - describes specific pathways by which tobacco smoke damages the human body and leads to disease and death.

10 Dec 2010

Low phosphate diets may increase dialysis patients' risk of premature death

Doctors often ask kidney disease patients on dialysis to limit the amount of phosphate they consume in their diets, but this does not help prolong their lives, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology.

10 Dec 2010

New molecular tools show promise for cleansing brain of amyloid plaques

New molecular tools developed at the University of Michigan show promise for "cleansing" the brain of amyloid plaques, implicated in Alzheimer's disease.

10 Dec 2010

Researchers target MIC-1 protein to halt growth of melanoma tumors

Halting the growth of melanoma tumors by targeting the MIC-1 protein that promotes blood vessel development in tumors may lead to better treatment of this invasive and deadly cancer, according to Penn State College of Medicine researchers in The Foreman Foundation Research Laboratory.

10 Dec 2010

New three-drug combination may be effective for newly diagnosed blood cancer patients: Study

A new three-drug combination used to treat the blood cancer multiple myeloma may be effective as a front-line therapy for newly diagnosed patients, according to a study led by the University of Michigan Comprehensive Cancer Center.

9 Dec 2010

Warfarin may not be beneficial to some patients with atrial fibrillation: Researchers

Researchers at the University of Cincinnati and Massachusetts General Hospital have found that warfarin, a known anticoagulation (blood-thinning) drug, may not be as beneficial to some patients with atrial fibrillation as previously thought.

9 Dec 2010

Blood News and Research

EU, India leaders meet to discuss trade deal, some concerned deal will jeopardize drug access in developing countries

Researchers generate insulin-secreting pancreatic islet cells from human SSCs

Stem cell therapy can reduce risk of acute leukemia in affected individuals

High CTC level found to be early marker of poor outcome in metastatic breast cancer

Official guidelines for diagnosis, treatment and management of food allergies released

Epigenetic-molecular targeted therapy combination holds promise against advanced lung cancer

Pisgah's technology imparts abuse deterrence to commonly abused prescription drugs

STENTYS initiates international APPOSITION III self-apposing stent study in AMI patients

Everolimus plus tamoxifen delays disease progression in HR+/HER2- metastatic breast cancer

First genetic test on developing risk of Alzheimer's disease and heart attacks

Fibrin microthreads support mesenchymal stem cell growth

Blocking growth of blood vessels with antibodies could improve treatment of cancerous tumors

New 5-minute Memory Orientation Screening Test to identify elderly patients with dementia

Using buprenorphine to treat opioid-dependent pregnant women may result in healthier babies

Exposure to tobacco smoke causes immediate damage leading to serious illness or death

Low phosphate diets may increase dialysis patients' risk of premature death

New molecular tools show promise for cleansing brain of amyloid plaques

Researchers target MIC-1 protein to halt growth of melanoma tumors

New three-drug combination may be effective for newly diagnosed blood cancer patients: Study

Warfarin may not be beneficial to some patients with atrial fibrillation: Researchers

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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