Carcinomas News and Research

RSS

UQ researchers move closer to developing topical cream for skin cancers in transplant patients

A topical cream to help prevent and treat skin cancers in organ transplant patients is a step closer to development.

28 Nov 2024

Leveraging genetic variations for more effective cancer therapies

By exploiting the genetic variation in cancer cells, an already approved cancer drug demonstrated enhanced effects against cancer cells in specific patient groups.

14 Nov 2024

New treatment combination improves outcomes for small cell bladder and prostate cancer patients

A research team led by UCLA Health Jonsson Comprehensive Cancer Center investigators has shown that that combining pembrolizumab, an immunotherapy drug, with standard chemotherapy can improve treatment outcomes for patients with small cell bladder cancer and small cell/neuroendocrine prostate cancer.

12 Nov 2024

New study reveals how tumor cells evade the immune system

It is comparatively easy to tell a cell's state of health: On their surface, cells present fragments of almost all the proteins they contain inside.

6 Nov 2024

Clinical utility of carbonic anhydrase IX in diagnosing pleural mesothelioma

Mesothelioma is an aggressive tumor with a poor prognosis. Histological diagnosis of mesothelioma using limited tissue samples can be challenging.

27 Oct 2024

Non-invasive imaging technique can accurately detect clear-cell renal cell carcinoma

A new study led by investigators from the UCLA Health Jonsson Comprehensive Cancer Center has demonstrated a new, non-invasive imaging technique can accurately detect clear-cell renal cell carcinoma, the most common form of kidney cancer.

3 Oct 2024

The threat of serous uterine cancer: A new perspective

Most uterine cancers have excellent five-year survival rates – up to 95% for localized cancer. Serous uterine cancer is an exception, with five-year survival rates of 35% to 50% for stage 1 or 2 cancer.

3 Oct 2024

Researchers advance ovarian cancer detection using cfDNA fragmentomes and protein biomarkers

Researchers developed a groundbreaking method to detect ovarian cancer early by analyzing cfDNA fragmentomes and protein biomarkers, significantly improving sensitivity and specificity over existing approaches.

1 Oct 2024

Standard chemoradiation outperforms de-intensified treatments in HPV-associated oropharyngeal cancer

Researchers looking to de-intensify radiation treatments for people with early-stage, HPV-associated oropharyngeal cancer to prevent long-term side effects halted a large, randomized phase II/III trial after patients in the control arm reached a record high, two-year progression-free survival rate of 98%.

30 Sep 2024

UCLA develops largest collection of patient-derived organoids for sarcoma research

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have developed the largest collection of sarcoma patient-derived organoids to date that can help improve the understanding of the disease and better identify therapies that are most likely to work for each individual patient.

20 Sep 2024

Common diabetes medication slows growth of precancerous esophageal cells, study shows

A common diabetes medication, metformin, slows the growth of precancerous cells in the oesophagus while some metabolic conditions accelerate it, suggests a new study.

16 Sep 2024

Five key factors identified for predicting immunotherapy response in cancer patients

Immunotherapy has transformed cancer treatment in recent years by enabling the immune system to attack tumor cells.

12 Sep 2024

MSK researchers identify a new, rare type of small cell lung cancer

A team of doctors and researchers at Memorial Sloan Kettering Cancer Center (MSK) have identified a new, rare type of small cell lung cancer that primarily affects younger people who have never smoked.

11 Sep 2024

Low-cost videoscopes show promise for screening HPV-associated oropharyngeal cancers

The rise in the incidence of oropharyngeal squamous cell carcinomas (OPSCCs) linked to human papillomavirus (HPV)-16 infection has become notable, surpassing cervical high-risk HPV infections by 2019.

20 Aug 2024

Review of fasting-mimicking diets in cancer treatment

Researchers present the role of cyclic fasting and fasting-mimicking diets (FMD) in cancer therapy.

8 Aug 2024

Racial bias found in cancer treatment approvals

Prior authorization - the process by which a health insurance company denies or approves coverage for a health care service before the service is performed - became standard practice beginning with Medicare and Medicaid legislation in the 1960s.

2 Aug 2024

New dual kinase inhibitor MTX-531 shows promise in overcoming cancer therapy resistance

A team of researchers at the University of Michigan Health Rogel Cancer Center has designed a molecule that impairs signaling mediated by two key drivers of cancer therapy resistance.

29 Jul 2024

New method developed to map mechanistic connections between diseases

Tampere University researchers developed a method to map mechanistic connections between diseases, revealing deeper associations beyond traditional classifications based on affected organs and symptoms.

28 Jun 2024

New WHO classification of kidney tumors integrates molecular diagnostics

Renal tumor pathology has evolved considerably, expanding from two main types of renal malignant tumors to over 20 distinct types.

18 Jun 2024

Interdisciplinary team reveals how Porphyromonas gingivalis interferes with chemotherapy-induced mitophagy

A new paper from an interdisciplinary team at MUSC Hollings Cancer Center describes how the bacteria Porphyromonas gingivalis interferes with chemotherapy-induced mitophagy, allowing oral cancer tumors to become resistant to the drug's effects.