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Patient Claim Line outlines key signs of stroke and how to reduce risks

Every five minutes, someone in the UK will experience a stroke, with 1.3 million people in the country having survived a stroke. The condition can be both life-threatening and life-altering, so knowing what to look out for and how to act in the event of a stroke is essential.

26 Oct 2024

SCD health disparities tied to community factors

A new study finds that preschool-aged children with sickle cell disease (SCD) who live in food deserts and have limited access to transportation are at greater risk for acute complications and hospitalizations, despite receiving free evidence-based therapy and social support, according to results published today in Blood Advances.

8 Oct 2024

Over 80% of women are iron deficient by their third trimester

Iron deficiency is prevalent among pregnant women, impacting health outcomes. This study emphasizes the importance of monitoring and nutrition during pregnancy.

30 Sep 2024

MaxCyte signs strategic platform license with Kamau Therapeutics to accelerate the development of cell therapies for genetic diseases

MaxCyte, Inc., a leading, cell-engineering focused company providing enabling platform technologies to advance the discovery, development and commercialization of next-generation cell-based therapeutics and innovative bioprocessing applications, and Kamau Therapeutics, a clinical-stage stem cell therapy gene correction company, today announced they are entering into a strategic platform license (SPL) agreement.

From MaxCyte, Inc. 23 Sep 2024

Stroke risk rises in patients with sickle cell disease despite established guidelines

The incidence of stroke continues to increase for adults and children living with sickle cell disease (SCD) despite the Stroke Prevention Trial in Sickle Cell Anemia (STOP) establishing standards of care like transfusions and tests to measure blood flow in the brain for those deemed high-risk, according to a study published today in Blood.

20 Sep 2024

Sickle cell trait increases risk of blood clots across diverse ancestries

National Institutes of Health (NIH) researchers and collaborators have found that being a carrier for sickle cell disease, known as having sickle cell trait, increases the risk of blood clots, a risk that is the same among diverse human populations that may not traditionally be associated with sickle cell disease.

12 Sep 2024

Benefits of less intensive stem cell transplants for sickle cell disease

So-called low-intensity blood stem cell transplants, which use milder conditioning agents than standard stem cell transplants, do not appear to damage the lungs and may help improve lung function in some patients with sickle cell disease (SCD), according to a three-year study of adults who underwent the procedure at the National Institutes of Health (NIH).

28 Aug 2024

Study: Iron infusions superior to blood transfusions for surgical patients with anemia

In a rigorous medical records study covering tens of thousands of patients, Johns Hopkins Medicine researchers conclude that some patients with preoperative anemia have better outcomes if they get iron infusions before surgery rather than standard red blood cell transfusions.

25 Jul 2024

Ovarian reserve unchanged by hydroxyurea in sickle cell disease, study reveals

In female patients living with sickle cell disease (SCD), hydroxyurea had no effect on ovarian reserve, suggesting that fertility preservation measures prior to treatment may be unnecessary, according to a study published in Blood Advances.

18 Jul 2024

Swift transfer from pediatric to adult care may reduce the use of acute care services in sickle cell disease

Sickle cell disease is the most common inherited red blood cell disorder in the United States and can lead to health problems including organ dysfunction, acute chest syndrome and strokes over a patient's lifespan.

16 Jul 2024

UCLA study finds insomnia drug suvorexant prevents opioid addiction in mice

New research led by UCLA Health has found a drug that treats insomnia works to prevent the addictive effects of the morphine opioids in mice while still providing effective pain relief.

9 Jul 2024

Understanding patient distress in sickle cell disease

While distress is well-documented in patients with sickle cell disease, sources of distress and how patients manage distress have not been well explored.

9 Jul 2024

New curative treatment for sickle cell disease shows promising results in international trial

Vanderbilt University Medical Center (VUMC) researchers are touting data from a multicenter, international phase 2 clinical trial showing a new, curative treatment for sickle cell disease (SCD).

25 Jun 2024

Promising gene editing therapy shows hope in sickle cell disease cure

Researchers have presented the latest findings from a clinical trial aimed at discovering a cure for sickle cell disease, a painful genetic blood disorder with limited treatment options.

14 Jun 2024

Timely transition from pediatric to adult care reduces hospitalizations for sickle cell patients

Individuals living with sickle cell disease (SCD) who experience a delay of more than six months in transitioning from pediatric to adult care are twice as likely to be hospitalized compared to those who transition in less than two months, according to a study published in Blood Advances.

29 May 2024

Study finds rise in hospitalizations for ischemic priapism

Researchers analyzed nationwide data from Germany to evaluate trends and outcomes in hospitalized cases of high- and low-flow priapism, finding increased hospitalizations for ischemic priapism and reduced cases linked to sickle cell disease.

26 May 2024

Comprehensive cost and utilization of commercial CAR-T therapy in pediatric B-ALL patients

A new editorial paper was published in Oncoscience (Volume 11) on April 25, 2024, entitled, "The price of hope: CAR-T therapy in pediatric leukemia."

17 May 2024

Sensing a Healthier Future with Sustainable Nanomaterials and Biosensors

In this interview conducted at Pittcon 2024 in San Diego, we spoke to this year's Keynote Speaker Professor Omowunmi (Wunmi) Sadik about how sustainable nanomaterials are transforming human health.

From Pittcon 16 May 2024

Electric pulses boost gene therapy uptake in liver cells

In an effort to improve delivery of costly medical treatments, a team of researchers in electrical engineering at the University of Wisconsin–Madison has developed a stimulating method that could make the human body more receptive to certain gene therapies.

30 Apr 2024

CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients

In a landmark study, an international consortium led by researchers at Children's Hospital of Philadelphia (CHOP) published the final results of a key clinical trial of the gene therapy CASGEVY (exagamglogene autotemcel) for the treatment of sickle cell disease in patients 12 years and older with recurrent vaso-occlusive crises (VOCs).

24 Apr 2024