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Shared protein pathology redefines treatment for multiple neurodegenerative diseases

On the surface, amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and limbic-predominant age-related TDP-43 encephalopathy (LATE) might seem like unrelated diseases.

24 Aug 2026

Disrupted brain-immune signaling may help drive neurodegeneration

A Cell perspective argues that neurodegeneration can emerge from disrupted communication between neural and immune networks, with peripheral immunity, microglia, and gene-regulatory programs all shaping disease processes. The authors propose that restoring immune homeostasis and recalibrating neuroimmune circuits could create new therapeutic and diagnostic opportunities, while emphasizing that many mechanisms remain unresolved in humans.

24 Aug 2026

Brain organoid studies on the ISS move closer to new treatments

Research using human brain organoids onboard the International Space Station International Space Station (ISS) helped lead to the clinical trial of a potential therapy for Rett syndrome, a debilitating neurological disorder in children.

20 Aug 2026

A single blood test could offer a glimpse of disease risk years in advance

Machine learning-derived cellular aging clocks mapped more than 7,000 plasma proteins to over 40 cell types, revealing marked differences in how individual cell populations age. These blood-based signatures were associated with future risks of Alzheimer’s disease, ALS, lung cancer, type 2 diabetes, and mortality across follow-up extending to 15 years.

19 Aug 2026

Paternal valproate use not linked to offspring neurodevelopmental risks

Use of the antiseizure drug valproate by fathers before conception is not associated with neurodevelopmental disorders like autism or attention-deficit/hyperactivity disorder (ADHD) in their children, according to a new study published August 19, 2026, in Neurology®, an official journal of the American Academy of Neurology.

19 Aug 2026

Later-life estrogen therapy associated with lower risk of developing dementia

Use of hormone therapy later in life was associated with lower risk of developing dementia, according to a study published August 12, 2026, in Neurology, the medical journal of the American Academy of Neurology.

12 Aug 2026

FDA clears first self-balancing personal exoskeleton for wheelchair users

The U.S. Food and Drug Administration has cleared Eve™, the first self-balancing personal exoskeleton for eligible wheelchair users living with spinal cord injury.

11 Aug 2026

New review urges proteostatic fitness standards for stem cell therapies

Stem cell therapies have expanded rapidly, with more than 115 clinical trials involving over 1,200 patients approved by late 2024. The U.S. Food and Drug Administration (FDA) recently approved Ryoncil (remestemcel‑L) for children with steroid‑refractory acute graft‑versus‑host disease, signaling a major shift toward routine clinical use.

11 Aug 2026

New report shows rising job search among disabled individuals

More people with disabilities were actively looking for work in July compared to June, while the number of people without disabilities seeking employment declined over the same period.

10 Aug 2026

Study reveals treatment gaps for atypical Alzheimer's disease patients

Many people with less common forms of Alzheimer's disease may not qualify for newer anti-amyloid treatments designed to slow the disease, according to a study published August 5, 2026, in Neurology®, the medical journal of the American Academy of Neurology.

5 Aug 2026

Occupational pesticide exposure may significantly increase ALS risk

Workplace exposure to pesticides (herbicides and insecticides) is linked to a 60-70% heightened risk of the most common form of motor neuron disease-amyotrophic lateral sclerosis, or ALS for short, finds a synthesis of the available evidence, published online in Occupational & Environmental Medicine.

4 Aug 2026

Australian-first twin study aims to to unlock new insights into immune health

An Australian-first study of twins will seek to find out why two genetically similar people respond differently to infections, diseases and treatments.

4 Aug 2026

Researchers recreate imagined melodies from brain activity

In a study led by Jii Kwon and Chun Kee Chung, from Seoul National University, researchers explored whether they could recreate melodies from the brain activity of people imagining how songs continue after listening to a few bars.

3 Aug 2026

New blood marker could help track MS progression and monitor treatment response

Modern therapies have transformed care for people with multiple sclerosis (MS). Yet the disease continues to progress in a substantial proportion of patients, even in the absence of relapses.

3 Aug 2026

ALS risk varies significantly across U.S. military service branches

Compared to Army veterans, men who are veterans of the U.S. Air Force, Navy and Coast Guard have higher rates of amyotrophic lateral sclerosis (ALS), and men who are Marine veterans have lower rates, according to a new study published July 29, 2026, in Neurology®, an official journal of the American Academy of Neurology.

29 Jul 2026

Early-life sugar restriction may reduce dementia risk later

Consuming less sugar in utero before birth and during the first one to two years of life was associated with a lower risk of developing dementia later in life, according to a study published July 29, 2026, in Neurology, the medical journal of the American Academy of Neurology.

29 Jul 2026

Photoreceptors possess internal recycling system to preserve vision

For decades, scientists believed that photoreceptors in the retina relied primarily on neighboring support cells, known as the retinal pigment epithelium (RPE), to remove waste. While the RPE is still responsible for clearing away the worn-out tips of photoreceptors each day, new findings from the University of Oklahoma reveal that photoreceptors also perform much of their own internal housekeeping.

29 Jul 2026

New blood protein biomarkers estimate timing of ALS symptoms

Months to several years before amyotrophic lateral sclerosis (ALS) symptoms arise, levels of certain blood proteins may dramatically shift.

27 Jul 2026

Multiple sclerosis mortality trends underscore need for comprehensive patient care

An analysis of more than 42,000 U.S. deaths linked to multiple sclerosis (MS) found that death rates varied by age, geography, and race and ethnicity, with Black patients dying younger than white patients and high blood pressure emerging as a growing contributor.

22 Jul 2026

Plasma exchange improves recovery in rare inflammatory nerve disease

Plasma exchange can help treat people with a rare inflammatory disease that can cause blindness, according to a systematic review and meta-analysis published on July 22, 2026, in Neurology, the medical journal of the American Academy of Neurology.

22 Jul 2026