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Scientists compared 51 longevity studies to see which aging biomarkers respond most reliably

Researchers analyzing 51 longitudinal intervention studies found that reliable generation 2+ DNA methylation biomarkers, particularly those predicting mortality or pace of aging, were the most responsive to interventions aimed at longevity or healthspan. Pharmacological and lifestyle interventions produced the strongest biomarker changes, but the authors cautioned that responsiveness does not yet establish these measures as validated surrogate endpoints for slower aging or longer life.

25 Aug 2026

Review uncovers how tryptophan metabolism affects female reproductive health

In recent years, issues concerning female reproductive health have become a global challenge that cannot be ignored.

24 Aug 2026

Comprehensive review outlines engineering-driven therapeutic pathways for spinal cord injuries

A comprehensive review published in Engineering outlines multi-disciplinary engineering approaches addressing spinal cord injury (SCI), a debilitating central nervous system disorder triggering permanent sensory, motor, and autonomic dysfunction, and imposing heavy burdens on individuals and societies worldwide.

21 Aug 2026

Multifunctional nanoplatform addresses three key barriers to effective TNBC immunotherapy

Triple-negative breast cancer (TNBC) is one of the most aggressive and treatment-resistant subtypes of breast cancer, accounting for 15-20% of all cases.

21 Aug 2026

Review examines how medical imaging foundation models are moved toward clinical use

AI is already widely used for lesion detection, disease classification, and outcome prediction in medical imaging, but most systems remain narrowly designed for one task and depend heavily on expert-labelled data.

20 Aug 2026

New genetic risk score uncovers hidden type 1 diabetes cases

Incorporating a genetic risk score into standard testing for a genetic form of diabetes which affects young people could identify hidden type 1 diabetes in around one in five patients with a negative genetic test.

19 Aug 2026

New battery-free pacemaker harvests power from every heartbeat

A team of University of Wisconsin–Madison researchers has developed an implantable, battery-free pacemaker that's charged by a patient's heartbeat.

19 Aug 2026

Estrogen fluctuations reshape brain connections, new study finds

A new study out of the University of Delaware shows that fluctuations in estrogen influence the brain, helping reshape connections between neurons.

18 Aug 2026

Multi-source data-driven machine learning improves lung cancer care

Lung cancer remains one of the malignancies with the highest incidence and mortality worldwide.

17 Aug 2026

AI-based "tissue clocks" measure the biological age of human organs

AI-based "tissue clocks" can estimate the biological age of human organs from histological images, researchers at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and the Ludwig Boltzmann Institute for Network Medicine (LBI-NetMed) at the University of Vienna showed.

14 Aug 2026

Study sheds new light on the physiological roles of protein quality control at the ribosome

Scientists at the Center for Molecular Medicine Cologne (CMMC) and the CECAD Cluster of Excellence on Aging Research have demonstrated in a biomedical study that ribosomes, the protein factories of our cells, face an unusually tough challenge when building large, membrane‑embedded proteins.

12 Aug 2026

Personalized T-cell therapy eliminates advanced kidney tumor in teenager

Researchers and physicians at the Hopp Children's Cancer Center Heidelberg (KiTZ) and other leading cancer centers report an exceptional treatment success in an adolescent with an advanced, therapy-resistant kidney tumor.

12 Aug 2026

Researchers find unexpected protein regulator of leukemia drug sensitivity

How cells respond to the leukemia drug 6-thioguanine still holds surprises: A new study, led by researchers from CeMM and the University of Oxford identifies NUDT5 as an unexpected regulator of drug sensitivity and reveals that its role has nothing to do with its enzymatic activity.

12 Aug 2026