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Semaglutide can offer important heart benefits that go beyond weight loss

A new analysis of the SELECT trial – the largest and longest clinical trial to date examining the cardiovascular benefits of semaglutide (a medication used to support weight loss and diabetes management) – confirms it also lowers the risk of major heart problems in people who are overweight or obese and already have heart disease, even if they don't have diabetes.

23 Oct 2025

Intensive program leads to high type 2 diabetes remission in India

Nearly one-third of people with type 2 diabetes (T2D) in an Indian cohort achieved remission through an intensive lifestyle intervention program, according to a new study publishing October 22, 2025, in the open-access journal PLOS One by Pramod Tripathi of Freedom from Diabetes Clinic & Diabetes Research Foundation, India, and colleagues.

23 Oct 2025

Mediterranean diet linked to dramatically lower odds of endometriosis

A new case–control study found that women with stronger adherence to the Mediterranean diet had dramatically lower odds of endometriosis. Diets rich in fruits, vegetables, fish, and legumes were protective, while higher intakes of meat, dairy, and refined whole grains were linked to increased risk.

22 Oct 2025

Night shift work may raise risk of irritable bowel syndrome

The study indicates that night shift work increases irritable bowel syndrome risk, particularly among those with obesity, due to circadian rhythm disturbances.

22 Oct 2025

Tracking daily blood pressure in pregnancy could predict low birth weight sooner

Early-pregnancy home blood pressure patterns reveal that even small cumulative elevations, not just high averages, raise the risk of low birth weight. Tracking daily readings above thresholds may improve early warning and maternal–fetal outcomes.

21 Oct 2025

Strong grip strength lowers risk of organ dysfunction in obesity

People with obesity who also have high muscle mass may be less likely to have obesity-related organ damage.

21 Oct 2025

Early menopause increases risk of metabolic syndrome in women

The prevalence of metabolic syndrome, a dangerous and potentially deadly condition, increases with menopause.

21 Oct 2025

Genetic inflammatory signature defines depression subtypes and treatment response

Researchers led by Prof. Alessandro Serretti at Kore University of Enna have identified a genetic inflammatory signature that defines specific depression subtypes and influences how patients respond to antidepressant medications, according to new peer-reviewed research published today in Genomic Psychiatry.

21 Oct 2025

Blood biomarkers forecast long-term blood pressure improvement after adolescent bariatric surgery

A groundbreaking study published in Hypertension, the journal of the American Heart Association, has identified a set of blood-based biomarkers that can predict improvements in blood pressure five years after adolescents underwent metabolic bariatric surgery.

20 Oct 2025

Why the first 1,000 days matter most in preventing childhood obesity

The EndObesity Consortium’s narrative review underscores that most childhood obesity risks emerge in the first 1,000 days, well before birth, highlighting gaps in parental, social, and policy interventions. Effective prevention demands preconception-focused, family-wide, and system-level strategies built on equitable public health frameworks.

20 Oct 2025

Can fitness apps and wearables make children healthier? This study says yes - partly

Digital health tools such as apps, wearables, and web platforms can modestly improve children’s physical activity, diet, and weight outcomes. Shorter programs boost activity, while longer ones better support weight management, though effects on sleep and sedentary time remain unclear.

20 Oct 2025

Simple hand grip test may reveal your future obesity risk

Increased grip strength correlates with lower obesity-related disease risk, suggesting muscle power as a key factor in preclinical obesity management.

20 Oct 2025

Study: Hidden fat inside the abdomen and liver may damage arteries

A new study led by researchers at McMaster University reveals that hidden fat deep inside the abdomen and liver may quietly damage arteries, even in people who appear healthy.

17 Oct 2025

Mass General Brigham study shows US obesity could jump from 40% to 70%

The prevalence of obesity in the United States could rise sharply under a new definition of obesity released earlier this year by the Lancet Diabetes and Endocrinology Commission.

16 Oct 2025

What happens when microplastics reach the testes? Study shows autophagy and cell loss

Researchers found that microplastics from everyday plastic tableware accumulate in human semen and, although not linked to semen quality in the full cohort, were associated with altered sperm parameters in specific subgroups. Experimental models confirmed that 50 nm polystyrene particles trigger autophagy and apoptosis via the FOXA1/MAP3K1/p38 pathway, impairing sperm structure and function.

15 Oct 2025

Building muscle shown to protect against obesity-related organ damage

People with excess body fat who build and keep muscle may be less likely to develop obesity-induced heart, liver, or kidney damage or die early, according to a new study published in The Journal of Clinical Endocrinology & Metabolism.

15 Oct 2025

Why improving LE8 scores could save young adults from diabetes

Young adults with prediabetes who maintained higher Life’s Essential 8 (LE8) cardiovascular health scores were far less likely to progress to type 2 diabetes over 13 years. Ideal LE8 profiles, particularly healthy weight, blood pressure, physical activity, and sleep, were strongly associated with regression to normal glucose levels.

14 Oct 2025

Study highlights healthcare costs linked to both underweight and obesity in children

The NHS incurs an estimated £340 million in additional healthcare costs annually due to weight-related health problems in children – but it is not just obesity driving the costs.

14 Oct 2025

Global health study warns of rising youth deaths amid declining overall mortality

Global mortality rates are falling but not among youths and young adults, according to the latest Global Burden of Disease (GBD) study published in The Lancet today and presented at the World Health Summit in Berlin.

13 Oct 2025

Home blood tests could spot early heart risks in young adults

Self-administered dried blood spot kits show potential for cardiometabolic screening in young adults, but success relied heavily on clear guidance and researcher support. High rates of at-risk biomarkers highlight an urgent need for early prevention in this population.

12 Oct 2025