Embryonic Stem Cell News and Research

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BioTime enters MTA with UC to make research-grade hES cell lines

BioTime, Inc. today announced a material transfer agreement (MTA) with the University of California (UC) system to make five research-grade human embryonic stem (hES) cell lines available to UC system researchers. These lines are genetically identical to a bank of GMP-compliant hES cell lines that will be made available to California-based researchers under a recent agreement between BioTime and the California Institute for Regenerative Medicine (CIRM).

23 Dec 2010

The Hill: GOP leaders for House Energy and Commerce health panel named

Rep. Fred Upton (R-Mich.), chairman-in-waiting of the powerful Energy and Commerce Committee, announced on Thursday the chairmen and vice-chairmen on his committee. As predicted, abortion-rights foe Rep. Joe Pitts (R-Pa.) got the chairmanship of the health subcommittee in a sop to conservatives who bitterly opposed Upton because he has not supported efforts to enact parental notification laws, to defund embryonic stem cell research or oppose "partial-birth" abortion.

20 Dec 2010

Whitehead Institute Founding Member named recipient of 2011 Warren Triennial Prize of MGH

Whitehead Institute Founding Member Rudolf Jaenisch has been named a recipient of the 2011 Warren Triennial Prize of Massachusetts General Hospital.

17 Dec 2010

Research: Stem cell culture on soft substrate maintain homogeneous pluripotent colonies

In a paper published in the journal PLoS One, the researchers demonstrated that culturing mouse embryonic stem cells on a soft gel rather than on a hard plate or dish keeps them in their pluripotent state, a ground state with the ability to become any type of tissue.

16 Dec 2010

Novel labeling technique helps researchers to explore DNA chemical modification

Researchers at Emory University School of Medicine and the University of Chicago have developed a method for labeling and mapping a "sixth nucleotide," whose biological role scientists are only beginning to explore.

14 Dec 2010

Scientists create functioning human intestinal tissue from pluripotent stem cells

For the first time, scientists have created functioning human intestinal tissue in the laboratory from pluripotent stem cells.

13 Dec 2010

Stem cell biology offers great hope for eventual repair of body parts

Remarkable progress in understanding how stem cell biology works has been reported by a team of leading scientists, directed by experts at UC Santa Barbara. Their research has been published in the journal Cell Stem Cell.

13 Dec 2010

Men with type 1 diabetes could grow their own insulin-producing cells from testicular tissue, says GUMC

Men with type 1 diabetes may be able to grow their own insulin-producing cells from their testicular tissue, say Georgetown University Medical Center (GUMC) researchers who presented their findings today at the American Society of Cell Biology 50th annual meeting in Philadelphia.

13 Dec 2010

Study: States fund majority of human embryonic stem cell research conducted in the US

States, not the federal government, now fund the majority of human embryonic stem cell research conducted in the United States, according to a recent study in the journal Nature Biotechnology.

9 Dec 2010

Bioheart group to advance BRIDGE TO RECOVERY clinical trial

Bioheart, Inc. announced today that at the American Heart Association Annual Meeting, it finalized the formation of a working group. The group's focus is to advance a BRIDGE TO RECOVERY clinical trial, combining a left ventricle assist device (LVAD) and Bioheart's MyoCell adult muscle stem cell composition and Bioheart's MyoCath needle tipped catheter delivery system.

9 Dec 2010

Swissmedic authorizes Phase I/II clinical trial of human neural stem cells for chronic spinal cord injury

A therapy developed by Aileen Anderson and Brian Cummings of UC Irvine's Sue and Bill Gross Stem Cell Research Center in collaboration with researchers at StemCells Inc. will be the basis of the world's first clinical trial using human neural stem cells to treat spinal cord injury.

8 Dec 2010

Scripps scientists find way to transform mature human cells into stem cells

Scripps Research Institute scientists have made a significant leap forward in the drive to find a way to safely reprogram mature human cells and turn them into stem cells, which can then change into other cell types, such as nerve, heart, and liver cells. The ability to transform fully mature adult cells such as skin cells into stem cells has potentially profound implications for treating many diseases.

3 Dec 2010

First Edition: December 2, 2010

Today's health policy headlines include news about how the debt panel's plan would boost costs for seniors on Medicare; how parts of the GOP are making clear their positions regarding health reform "repeal and replace" strategy; and how limited health plans faced critics at a Senate hearing.

2 Dec 2010

ASH honors Sen. Sherrod Brown and Erik Fatemi

The American Society of Hematology (ASH) will honor Senator Sherrod Brown (D-OH) with the 2010 ASH Award for Public Service and Erik Fatemi, Majority Clerk for the Senate Appropriations Subcommittee on Labor, Health and Human Services, Education, and Related Agencies (Labor-HHS), with the Award for Outstanding Service in recognition of their dedication to championing health care and research issues. These awards will be officially announced at the 52nd ASH Annual Meeting taking place December 4-7 in Orlando, FL.

2 Dec 2010

ACT files IND application to initiate Phase I/II study for Dry AMD

Advanced Cell Technology, Inc. announced today that it has filed an Investigational New Drug (IND) Application with the US Food and Drug Administration (FDA) to initiate a Phase I/II multicenter study using human embryonic stem cell (hESC) derived retinal pigment epithelial (RPE) cells to treat patients with Dry Age-Related Macular Degeneration (Dry AMD).

30 Nov 2010

BioTime, CIRM enter agreement for GMP-grade hES cell lines

BioTime, Inc. today announced an agreement with the California Institute for Regenerative Medicine (CIRM) to make five clinical-grade human embryonic stem (hES) cell lines available to California-based researchers. CIRM is the stem cell agency created when California voters supported a $3 billion funding measure for stem cell-related research and clinical translation.

29 Nov 2010

EHNA treatment blocks spontaneous differentiation of stem cells

Human embryonic stem cells have enormous potential for use in pharmaceutical development and therapeutics; however, to realize this potential there is a requirement for simple and reproducible cell culture methods that provide adequate numbers of cells of suitable quality.

26 Nov 2010

Embryonic stem cell research has not made good on taxpayer investment

In 2004 Robert Klein, chairman of the California Institute of Regenerative Medicine (CIRM), helped pass Proposition 71, establishing the CIRM with a state taxpayer-funded $3 billion budget for ten years. The measure was passed with promises of affordable cures for virtually all diseases, cures specifically from embryonic stem cells and cloning, as well as tremendous financial payback for the citizens of California. The Los Angeles Times recently noted that Klein plans to seek up to $3 billion more from state taxpayers for his stem cell fiefdom.

25 Nov 2010

Stem cell trial for eye disease receives FDA approval

The second clinical trial involving stem cells from human embryonic cells has received the go-ahead. The news came from Advanced Cell Technology Inc. this Monday. The company announced that the U.S. Food and Drug Administration has cleared the way for its Phase I/II trial of retinal cells for patients with Stargardt’s macular dystrophy, a childhood version of macular degeneration.

22 Nov 2010

FDA grants ACT clearance for Phase I/II clinical trial of hESC derived retinal cells in patients with SMD

Advanced Cell Technology, Inc. announced today that the US Food and Drug Administration (FDA) has cleared the Company's Investigational New Drug (IND) application to immediately initiate a Phase I/II multicenter clinical trial using retinal cells derived from human embryonic stem cells (hESCs) to treat patients with Stargardt's Macular Dystrophy (SMD), one of the most common forms of juvenile macular degeneration in the world. The decision removes the clinical hold that the FDA had placed on the trial.

22 Nov 2010

Embryonic Stem Cell News and Research

BioTime enters MTA with UC to make research-grade hES cell lines

The Hill: GOP leaders for House Energy and Commerce health panel named

Whitehead Institute Founding Member named recipient of 2011 Warren Triennial Prize of MGH

Research: Stem cell culture on soft substrate maintain homogeneous pluripotent colonies

Novel labeling technique helps researchers to explore DNA chemical modification

Scientists create functioning human intestinal tissue from pluripotent stem cells

Stem cell biology offers great hope for eventual repair of body parts

Men with type 1 diabetes could grow their own insulin-producing cells from testicular tissue, says GUMC

Study: States fund majority of human embryonic stem cell research conducted in the US

Bioheart group to advance BRIDGE TO RECOVERY clinical trial

Swissmedic authorizes Phase I/II clinical trial of human neural stem cells for chronic spinal cord injury

Scripps scientists find way to transform mature human cells into stem cells

First Edition: December 2, 2010

ASH honors Sen. Sherrod Brown and Erik Fatemi

ACT files IND application to initiate Phase I/II study for Dry AMD

BioTime, CIRM enter agreement for GMP-grade hES cell lines

EHNA treatment blocks spontaneous differentiation of stem cells

Embryonic stem cell research has not made good on taxpayer investment

Stem cell trial for eye disease receives FDA approval

FDA grants ACT clearance for Phase I/II clinical trial of hESC derived retinal cells in patients with SMD

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