Embryonic Stem Cells News and Research

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ACT announces European phase I clinical trial for Stargardt's disease using retinal pigment epithelial cells

Advanced Cell Technology, Inc. a leader in the field of regenerative medicine, today announced treatment of the first patient in the third dosage cohort, and seventh patient overall, in its European Phase I clinical trial for Stargardt's macular dystrophy (SMD) using retinal pigment epithelial (RPE) cells derived from human embryonic stem cells (hESCs).

26 Apr 2013

Individual hydroxymethylcytosine molecules in DNA detected by new method involving chemical modification and nanopore analysis

Changes in the bases that make up DNA act as markers, telling a cell which genes it should read and which it shouldn’t. In the journal Angewandte Chemie, a British team has now introduced a new method that makes it possible to enrich the rare gene segments that contain the modified base hydroxymethylcytosine and to identify individual hydroxymethylcytosine molecules in DNA. Such modifications are associated with autoimmune diseases and cancer.

24 Apr 2013

Study: Stem cell transplant heals neurological deficits in mice

For the first time, human embryonic stem cells have been transformed into nerve cells that helped mice regain the ability to learn and remember.

22 Apr 2013

Researchers transform skin cells directly into oligodendrocyte precursor cells

Researchers at the Stanford University School of Medicine have succeeded in transforming skin cells directly into oligodendrocyte precursor cells, the cells that wrap nerve cells in the insulating myelin sheaths that help nerve signals propagate.

16 Apr 2013

Junk DNA plays important role in brain development

Specific DNA once dismissed as junk plays an important role in brain development and might be involved in several devastating neurological diseases, UC San Francisco scientists have found.

16 Apr 2013

New research reveals how autophagy keeps neural stem cells to replace damaged brain, nerve cells

Deep inside your brain, a legion of stem cells lies ready to turn into new brain and nerve cells whenever and wherever you need them most. While they wait, they keep themselves in a state of perpetual readiness - poised to become any type of nerve cell you might need as your cells age or get damaged.

11 Apr 2013

Gladstone investigator to receive Essey Award for fight against amyotrophic lateral sclerosis

Shinya Yamanaka, MD, PhD, a senior investigator at the Gladstone Institutes, next month will receive the Essey Award for his "Commitment to a Cure" from The ALS Association Golden West Chapter.

26 Mar 2013

Research reveals method to produce retinal cells from regenerative human stem cells

Research led by a biology professor in the School of Science at Indiana University-Purdue University Indianapolis has uncovered a method to produce retinal cells from regenerative human stem cells without the use of animal products, proteins or other foreign substances, which historically have limited the application of stem cells to treat disease and other human developmental disorders.

20 Mar 2013

Medical student to attend Vatican conference on adult stem cell research

Michael Hutz, a second year student at Loyola University Chicago Stritch School of Medicine, has been invited to attend a prestigious Vatican conference on adult stem cell research.

14 Mar 2013

Stem cell line could also advance research into liver cancers, cystic fibrosis

Chronic or acute, liver failure can be deadly. Toxins take over, the skin turns yellow and higher brain function slows. "There is no effective therapy at the moment to deal with the toxins that build up in your body," said Neil Talbot, a Research Animal Scientist for the USDA Agricultural Research Service. "Their only option now is to transplant a liver."

1 Mar 2013

New mouse model can advance research on iPS cells to next step

VIB scientists associated to the UGent have developed a mouse model that can advance the research on iPS cells to the next step.

21 Feb 2013

New paper advances scientific understanding of glycoproteins’ structure and function

A Simon Fraser University chemist is the lead author on a new paper that advances scientific understanding of the structure and function of glycoproteins, in particular the number and positioning of sugars on them.

14 Feb 2013

Southampton scientists create new method to generate bone cells

Scientists at the University of Southampton have created a new method to generate bone cells which could lead to revolutionary bone repair therapies for people with bone fractures or those who need hip replacement surgery due to osteoporosis and osteoarthritis.

12 Feb 2013

Fbxl10 molecule plays a crucial role in differentiation of embryonic stem cells

A single embryonic stem cell can develop into more than 200 specialized cell types that make up our body. This maturation process is called differentiation and is tightly regulated. If the regulation is lost, specialized cells cannot develop correctly during development. In adulthood, the specialized cells may forget their identity and develop into cancer cells.

10 Feb 2013

Scientists discover natural trigger that enables stem cell development

A natural trigger that enables stem cells to become any cell-type in the body has been discovered by scientists.

10 Feb 2013

Reprogrammed human skin cells highly effective in treating myelin disorders

A study out today in the journal Cell Stem Cell shows that human brain cells created by reprogramming skin cells are highly effective in treating myelin disorders, a family of diseases that includes multiple sclerosis and rare childhood disorders called pediatric leukodystrophies.

10 Feb 2013

NFL funds WSU research to fix injured brains with new nerve cells

The National Football League thinks enough of the work that its charitable arm has given Krzysztof Czaja (pronounced K-shish-toff Chai-uh), a Washington State University neuroscientist, $100,000 to keep looking.

4 Feb 2013

Scientists report first generation of hiPSCs from patients with maturity onset diabetes of the young

Joslin scientists report the first generation of human induced pluripotent stem cells from patients with an uncommon form of diabetes, maturity onset diabetes of the young (MODY). These cells offer a powerful resource for studying the role of genetic factors in the development of MODY and testing potential treatments.

2 Feb 2013

Notch protein responsible for activating GATA2 gene to generate hematopoietic stem cells

Researchers from the group on stem cells and cancer at IMIM (Hospital del Mar Medical Research Institute) have deciphered one of the gene regulation circuits which would make it possible to generate hematopoietic blood cells, i.e. blood tissue stem cells.

1 Feb 2013

UB scientists propose first genomic explanation for schizophrenia

New University at Buffalo research demonstrates how defects in an important neurological pathway in early development may be responsible for the onset of schizophrenia later in life.

23 Jan 2013

Embryonic Stem Cells News and Research

ACT announces European phase I clinical trial for Stargardt's disease using retinal pigment epithelial cells

Individual hydroxymethylcytosine molecules in DNA detected by new method involving chemical modification and nanopore analysis

Study: Stem cell transplant heals neurological deficits in mice

Researchers transform skin cells directly into oligodendrocyte precursor cells

Junk DNA plays important role in brain development

New research reveals how autophagy keeps neural stem cells to replace damaged brain, nerve cells

Gladstone investigator to receive Essey Award for fight against amyotrophic lateral sclerosis

Research reveals method to produce retinal cells from regenerative human stem cells

Medical student to attend Vatican conference on adult stem cell research

Stem cell line could also advance research into liver cancers, cystic fibrosis

New mouse model can advance research on iPS cells to next step

New paper advances scientific understanding of glycoproteins’ structure and function

Southampton scientists create new method to generate bone cells

Fbxl10 molecule plays a crucial role in differentiation of embryonic stem cells

Scientists discover natural trigger that enables stem cell development

Reprogrammed human skin cells highly effective in treating myelin disorders

NFL funds WSU research to fix injured brains with new nerve cells

Scientists report first generation of hiPSCs from patients with maturity onset diabetes of the young

Notch protein responsible for activating GATA2 gene to generate hematopoietic stem cells

UB scientists propose first genomic explanation for schizophrenia

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