Glucose Metabolism News and Research

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Researchers uncover novel therapeutic target for type 2 diabetes

Researchers from Kanazawa University and the National Center for Global Health and Medicine in Tokyo report, in Nature Communications, a new mechanism for regulating glucose uptake by the liver which has implications for type 2 diabetes and its treatment.

6 Feb 2018

Researchers identify potential enzyme as therapeutic target for type 2 diabetes

Abnormalities in glucose uptake by the liver (or hepatic glucose uptake; HGU) cause elevations in blood glucose levels following meals, a state that is known as postprandial hyperglycemia.

27 Jan 2018

Camelina oil has positive effect on blood cholesterol levels

The use of camelina oil reduces overall and LDL cholesterol levels in persons with impaired glucose metabolism, according to a new study from the University of Eastern Finland. The findings were published in Molecular Nutrition & Food Research.

8 Jan 2018

Obese adolescents show improvements in cardiovascular disease risk factors after bariatric surgery

Adolescents with severe obesity who had bariatric surgery showed significant improvements in cardiovascular disease risk factors, according to the most recent "Teen Longitudinal Assessment of Bariatric Surgery" (Teen-LABS) study, published online today by Pediatrics.

8 Jan 2018

Social isolation may increase the risk of type 2 diabetes developing

People who are socially isolated are more likely to develop type 2 diabetes, compared with people who have a larger social circle, according to a new study from the Netherlands.

20 Dec 2017

New research shows how a gene can fuel obesity in mice

Obesity is often attributed to a simple equation: People are eating too much and exercising too little. But evidence is growing that at least some of the weight gain that plagues modern humans is predetermined.

16 Nov 2017

Researchers find new way to restrict ability of cancer to use glucose for energy

Cancer cells consume exorbitant amounts of glucose, a key source of energy, and shutting down this glucose consumption has long been considered a logical therapeutic strategy.

7 Nov 2017

Dinosaur extinction metal can be used to kill cancer cells

Cancer cells can be targeted and destroyed with the metal from the asteroid that caused the extinction of the dinosaurs, according to new research by an international collaboration between the University of Warwick and Sun Yat-Sen University in China.

2 Nov 2017

Study: HIIT reduces brain glucose metabolism of people with type 2 diabetes, prediabetes

Researchers at the University of Turku, Finland, studied how high-intensity interval training (HIIT) alters the brain's glucose metabolism in physically inactive insulin resistant people. Only two weeks of HIIT training reduced glucose metabolism in all areas of the brain.

27 Oct 2017

Key enzyme may be therapeutic target to treat diabetes-related blood vessel damage

A key enzyme that helps our proteins fold and function properly may also be a good therapeutic target to improve blood vessel health in diseases like diabetes and atherosclerosis, scientists say.

23 Oct 2017

Menopause causes metabolic changes in the brain that may increase Alzheimer's risk

Menopause causes metabolic changes in the brain that may increase the risk of Alzheimer's disease, a team from Weill Cornell Medicine and the University of Arizona Health Sciences has shown in new research.

10 Oct 2017

Fructose plays more damaging role than glucose in fatty liver disease, mice study shows

If you're one of the two billion people in the world who are over-weight or obese, or the one billion people with fatty liver disease, your doctor's first advice is to cut calories - and especially to cut down on concentrated sugars such as high-fructose corn syrup, a sugar found in sweetened beverages and many other processed foods.

4 Oct 2017

Special issue of Current Diabetes Review explores the management of diabetes in medically complex patients

Diabetes affects roughly 30 million Americans, and is one of the leading causes of disability and mortality. As a result, organizations such as the American Diabetes Association (ADA), Endocrine Society and American Association of Clinical Endocrinologists (AACE) have made efforts to move away from the one size fits all management of diabetes.

30 Sep 2017

Hypometabolism in medial prefrontal areas linked to AD-related nutritional problems

A new study from the Multimodal Neuroimaging for AD Diagnosis study, which is a prospective study implemented at the National Center for Geriatrics and Gerontology, provides that hypometabolism in the medial prefrontal areas is specifically associated with Alzheimer's disease-related nutritional problems, and decrease in fat mass may have a key role. This study is published in the Journal of Alzheimer's Disease.

15 Sep 2017

Researchers identify natural compound that appears to shut down cancer cells' energy source

The Warburg Effect describes a phenomenon in which cancer cells voraciously consume glucose for energy -- something scientists have long known, yet have had little success exploiting as a way to stunt tumor growth.

14 Sep 2017

CSHLP publishes new book on The Biology of Exercise

Cold Spring Harbor Laboratory Press today announced the release of The Biology of Exercise, available on its website in hardcover, paperback, and ebook formats.

1 Sep 2017

Increased enzyme production by the liver causes fatty liver, obesity and insulin resistance

In mice that are given a high-fat diet, an increased production of the enzyme DPP4 by the liver promotes an increase in body fat, the development of fatty liver disease and insulin resistance.

24 Aug 2017

Scientists show how immune system can be modulated by manipulation of sugar metabolism

In its attempt to fight a serious bacterial infection, caused by listeria, for example, the immune system can become so over-activated that the resulting inflammatory response and its consequences can quickly lead to death.

21 Aug 2017

Study: Liver inflammation increases cholesterol levels in people with diabetes

Inflammatory processes in the liver lead to elevated cholesterol levels in people with diabetes, thus promoting subsequent vascular diseases. This is the result of a study by scientists of Helmholtz Zentrum München, Technische Universität München and the Collaborative Research Center SFB 1118 at Heidelberg University Hospital.

14 Aug 2017

Immunotherapy shows promise in treatment of Type 1 diabetes

Around 1.25 million Americans are living with type 1 diabetes and 40,000 new cases are detected each year. In this condition body’s own immune system attacks and damages the insulin-producing β-cells inside the pancreas leading to impaired glucose metabolism in the body. There is no other treatment for this condition than regular painful insulin injections to maintain the normal insulin levels in the body. Type 1 diabetes is currently considered to be incurable.

10 Aug 2017