Glucose Metabolism News and Research

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Fructose plays more damaging role than glucose in fatty liver disease, mice study shows

If you're one of the two billion people in the world who are over-weight or obese, or the one billion people with fatty liver disease, your doctor's first advice is to cut calories - and especially to cut down on concentrated sugars such as high-fructose corn syrup, a sugar found in sweetened beverages and many other processed foods.

4 Oct 2017

Special issue of Current Diabetes Review explores the management of diabetes in medically complex patients

Diabetes affects roughly 30 million Americans, and is one of the leading causes of disability and mortality. As a result, organizations such as the American Diabetes Association (ADA), Endocrine Society and American Association of Clinical Endocrinologists (AACE) have made efforts to move away from the one size fits all management of diabetes.

30 Sep 2017

Hypometabolism in medial prefrontal areas linked to AD-related nutritional problems

A new study from the Multimodal Neuroimaging for AD Diagnosis study, which is a prospective study implemented at the National Center for Geriatrics and Gerontology, provides that hypometabolism in the medial prefrontal areas is specifically associated with Alzheimer's disease-related nutritional problems, and decrease in fat mass may have a key role. This study is published in the Journal of Alzheimer's Disease.

15 Sep 2017

Researchers identify natural compound that appears to shut down cancer cells' energy source

The Warburg Effect describes a phenomenon in which cancer cells voraciously consume glucose for energy -- something scientists have long known, yet have had little success exploiting as a way to stunt tumor growth.

14 Sep 2017

CSHLP publishes new book on The Biology of Exercise

Cold Spring Harbor Laboratory Press today announced the release of The Biology of Exercise, available on its website in hardcover, paperback, and ebook formats.

1 Sep 2017

Increased enzyme production by the liver causes fatty liver, obesity and insulin resistance

In mice that are given a high-fat diet, an increased production of the enzyme DPP4 by the liver promotes an increase in body fat, the development of fatty liver disease and insulin resistance.

24 Aug 2017

Scientists show how immune system can be modulated by manipulation of sugar metabolism

In its attempt to fight a serious bacterial infection, caused by listeria, for example, the immune system can become so over-activated that the resulting inflammatory response and its consequences can quickly lead to death.

21 Aug 2017

Study: Liver inflammation increases cholesterol levels in people with diabetes

Inflammatory processes in the liver lead to elevated cholesterol levels in people with diabetes, thus promoting subsequent vascular diseases. This is the result of a study by scientists of Helmholtz Zentrum München, Technische Universität München and the Collaborative Research Center SFB 1118 at Heidelberg University Hospital.

14 Aug 2017

Immunotherapy shows promise in treatment of Type 1 diabetes

Around 1.25 million Americans are living with type 1 diabetes and 40,000 new cases are detected each year. In this condition body’s own immune system attacks and damages the insulin-producing β-cells inside the pancreas leading to impaired glucose metabolism in the body. There is no other treatment for this condition than regular painful insulin injections to maintain the normal insulin levels in the body. Type 1 diabetes is currently considered to be incurable.

10 Aug 2017

New study reveals how glucose metabolism affects platelet activation and survival

Platelets, the cells in blood that enable clotting, are highly reliant on their ability to metabolize glucose, according to a new study by researchers at the University of Iowa.

4 Aug 2017

Novel MRI method uses simple sugar solution instead of conventional contrast agents

In magnetic resonance imaging, contrast agents are used to enhance the imaging of tissue structures.

23 Jun 2017

Moderate physical activity linked to healthy glucose metabolism in the brain

People at risk for Alzheimer's disease who do more moderate-intensity physical activity, but not light-intensity physical activity, are more likely to have healthy patterns of glucose metabolism in their brain, according to a new UW-Madison study.

22 Jun 2017

Review highlights effective treatment options for managing patients with T2D and osteoporosis

Type 2 diabetes (T2D) and osteoporosis often coexist in patients, but managing both conditions can be a challenge.

21 Jun 2017

Research provides insight into role of APP gene variant in Alzheimer’s disease

New research from the University of Eastern Finland shows that the APP gene variant protecting against Alzheimer's disease significantly decreases plasma beta-amyloid levels in a population cohort.

20 Jun 2017

Vegetarian diets found to be most effective for weight loss

Dieters who go vegetarian not only lose weight more effectively than those on conventional low-calorie diets but also improve their metabolism by reducing muscle fat, a new study published in the Journal of the American College of Nutrition has found.

12 Jun 2017

Research reveals link between POMC neurons and release of insulin by the pancreas

The brain is key in the regulation of appetite, body weight and metabolism. Specifically, there is a small group of hypothalamus neurons, called POMC, that detect and integrate signals that inform on the energy state of the organism and activate the appropriate physiological responses.

8 Jun 2017

Researchers uncover novel and non-invasive way to track dengue infection

Commonly used to detect solid tumors, positron emission tomography (PET) paired with the glucose metabolism probe, fluorodeoxyglucose (FDG), is considered 'old' technology in the field of cancer.

6 Jun 2017

Smoking during pregnancy damages liver tissue of developing fetus, study shows

A new stem cell study has shown the damaging impact cigarette smoke can have on the developing liver tissue of unborn fetuses. The study also revealed differences in the type of damage caused between male and female fetuses.

30 May 2017

Scientists report promising approach to combat influenza and improve survival

The influenza virus turns infected lung cells into factories that churn out thousands of copies of the virus to spread the infection. St. Jude Children's Research Hospital scientists have reported a promising new approach that uses an investigational cancer drug to dial down viral production and dramatically increase survival of flu-infected mice.

23 May 2017

Study identifies first genetic locus for anorexia nervosa

A landmark study led by UNC School of Medicine researchers has identified the first genetic locus for anorexia nervosa and has revealed that there may also be metabolic underpinnings to this potentially deadly illness.

12 May 2017