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Acquired immune deficiency syndrome or acquired immunodeficiency syndrome (AIDS) is a disease of the human immune system caused by the human immunodeficiency virus (HIV).

Study reveals how glioblastomas resist the effects of antiangiogenic drugs

A study led by investigators from Massachusetts General Hospital (MGH) and the University of Cyprus reveals details of a way the dangerous brain tumors called glioblastomas resist the effects of antiangiogenic drugs designed to cut off their blood supply.

31 Jan 2019

Fibrosis-targeting drugs may benefit patients with late-stage, metastatic breast cancer

A Massachusetts General Hospital (MGH) research team has found that the overgrowth of connective called fibrosis may block the effectiveness of immunotherapies against metastatic breast cancer.

29 Jan 2019

Columbia researchers develop 'Cascade of Care' model to reduce opioid overdose and death

Drug overdose is now the leading cause of death for individuals under the age of 50, as the opioid epidemic continues unabated. One reason is that the majority of the estimated 2.4 million Americans with opioid use disorder aren't getting evidence-based treatment, including medications to treat opioid addiction.

24 Jan 2019

People recovering from alcohol or drug disorder are quitting smoking than ever before

Smoking rates among people recovering from an alcohol or drug disorder are more than double that of the general population.

24 Jan 2019

Migrants and refugees do not bring disease and are at greater health risk themselves says WHO

The irregular migrant refugees coming to European nations are often accused on bringing with them host of exotic communicable diseases that tend to spread among the host communities. The World Health Organization (WHO) this week has absolved the migrants of spreading disease in its first report that deals with this issue.

22 Jan 2019

Short, text-based exercises can increase happiness for adults recovering from substance use disorders

Brief, text-based, self-administered exercises can significantly increase in-the-moment happiness for adults recovering from substance use disorders, report researchers at the Massachusetts General Hospital Recovery Research Institute.

21 Jan 2019

Hypertension drug may improve effectiveness of ovarian cancer treatment

A new study from a Massachusetts General Hospital research team has found that the hypertension drug losartan, which targets the angiotensin signaling pathway, may improve the effectiveness of chemotherapy agents used to treat ovarian cancer

16 Jan 2019

Virtual video visits can replace office visits without compromising quality of care

A team of researchers at Massachusetts General Hospital (MGH) reports in the American Journal of Managed Care that virtual video visits, one form of telehealth visit used at the hospital, can successfully replace office visits for many patients without compromising the quality of care and communication.

14 Jan 2019

New path for treating Latino immigrants with mental health and substance misuse symptoms

A team of researchers at the Disparities Research Unit at Massachusetts General Hospital (MGH) - in collaboration with two teams in Spain and collaborators in the U.S. and Puerto Rico - has tested a novel preventive intervention designed to provide tailored treatment for Latino immigrants with both mental health and substance misuse symptoms.

11 Jan 2019

Study finds specific function of HIV protein that slows viral spread in early stages of infection

A study from a Massachusetts General Hospital research team has identified the specific function of a protein found in HIV and related viruses that appears to slow down viral spread in the earliest stages of infection.

11 Jan 2019

Researchers design new questionnaire to improve knowledge of impact of menopause on women

A new questionnaire being developed through a collaboration between the Massachusetts General Hospital Midlife Women's Health Center and the North American Menopause Society is designed to improve knowledge of the extent and impact on women of genitourinary symptoms of menopause.

8 Jan 2019

MGH-led research team reveals how solid stress impacts tissue surrounding brain tumors

A Massachusetts General Hospital-led research team has demonstrated, for the first time, how solid stress - the physical forces exerted by the solid components of a tumor - impacts the tissue surrounding brain tumors and contributes to resulting neurological dysfunction and neuronal cell death.

8 Jan 2019

Lessons from successes and failures of AIDS epidemic could inform our response to opioid crisis

There are important lessons to be learned from the successes and failures of the AIDS response that could inform our response to the opioid epidemic, according to a new paper by researchers at the Columbia University Mailman School of Public Health.

4 Jan 2019

New study highlights development of functional skills in people with Down syndrome

When expectant parents learn their child will be born with Down syndrome, they invariably have questions about what this diagnosis will mean for their son or daughter and for the rest of their family.

3 Jan 2019

Study: Low wages, poor benefits leave many female health care workers below poverty line

A study carried out by researchers at Massachusetts General Hospital (MGH) and the Perelman School of Medicine at the University of Pennsylvania finds that low wages and poor benefits leave many female health care workers living below the poverty line.

2 Jan 2019

Researchers develop artificial intelligence system to diagnose, classify brain hemorrhages

A team of investigators from the Massachusetts General Hospital Department of Radiology has developed a system using artificial intelligence to quickly diagnose and classify brain hemorrhages and to provide the basis of its decisions from relatively small image datasets.

21 Dec 2018

Three studies examine readiness of U.S. emergency departments to care for children

Three papers from research teams led by a Massachusetts General Hospital physician examine the current readiness of U.S. emergency departments to care for children and describe an initiative that led to the appointment of a Pediatric Emergency Care Coordinator - a step considered the single best intervention to improve pediatric emergency care - in all Massachusetts EDs.

20 Dec 2018

Study identifies late-Gen X and early-Gen Y as age cohorts with elevated mortality patterns

Declining life expectancies in the U.S. include Gen X and Y Americans, in addition to the older Baby Boomers. But the causes of premature mortality vary by race, gender and ethnicity, according to a new study from Duke University.

20 Dec 2018

Tau protein reduces neural activity in Alzheimer's mouse models

A study from Massachusetts General Hospital investigators sheds new light on how the hallmarks of Alzheimer's disease - amyloid-beta (A-beta) plaques and neurofibrillary tangles containing the protein tau - produce their damaging effects in the brain.

19 Dec 2018

Pregnant women and extremely obese people at high risk of flu complications

Pregnant women and the extremely obese are among those at high risk for complications from the flu - including death - and should be tested and begin antiviral treatment promptly if they are sick enough to be hospitalized with flu symptoms, according to updated guidelines released by the Infectious Diseases Society of America.