Huntington’s Disease News and Research

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House Republicans divided over how to 'replace' health law

Ask each of the 242 House Republicans what kind of health policy they'd like to enact instead of President Barack Obama's health care reform law and you might get 242 different answers. Even after three years of railing against Obama's plan, Republicans have coalesced around only a few basic tenets of health policy - let alone a full replacement plan.

2 May 2012

Couples with infertility and miscarriages offered detailed embryo screening with 99% accuracy

Termed “preimplantation genetic screening (PGS)” the process involves a full chromosome count of embryos to ensure only the healthiest are implanted. It has a 99 per cent accuracy rate, giving hopeful parents the best chance to conceive and carry a healthy baby to term.

30 Apr 2012

Researchers examines whether MRI can improve accuracy of Huntington’s diagnosis

Huntington disease (HD) is an inherited neurodegenerative disorder caused by a defect on chromosome four where, within the Huntingtin gene, a CAG repeat occurs too many times. Most individuals begin experiencing symptoms in their 40s or 50s, but studies have shown that significant brain atrophy occurs several years prior to an official HD diagnosis. As a result, the field has sought a preventive treatment that could be administered prior to the development of actual symptoms that might delay the onset of illness.

27 Apr 2012

Researchers identify gene that increases risk of MI in newborns with CF

Researchers at Johns Hopkins have identified a gene that modifies the risk of newborns with cystic fibrosis (CF) developing neonatal intestinal obstruction, a potentially lethal complication of CF.

24 Apr 2012

Huntington’s disease may protect against cancer: Study

Dr Jianguang Ji, Lund University, and Skåne University Hospital, Malmö, Sweden, and colleagues investigated data from the Swedish Cancer Registry. Researchers analyzed Swedish hospital data from 1969 to 2008. They found 1,510 patients with Huntington's disease. During the study period, 91 of those patients subsequently developed cancer. The authors said that was 53% lower than the levels expected for the general population.

15 Apr 2012

Nmnat enzyme plays a critical role in nerve injury

A new animal model of nerve injury has brought to light a critical role of an enzyme called Nmnat in nerve fiber maintenance and neuroprotection.

31 Mar 2012

Technique developed to identify rogue clustering proteins in brain diseases

Australian researchers have developed a novel technique that tracks proteins “behaving badly” and may have found a way that leads to new treatments for brain disease. The team believes the discovery could help in the development of drugs to treat diseases such as Alzheimer's, Parkinson's and Huntington's.

19 Mar 2012

Novel technique rapidly identifies and tracks location of diseased proteins inside cells

A research team led by the University of Melbourne, Australia, has developed a novel technique that tracks diseased proteins behaving badly by forming clusters in brain diseases such as Huntington's and Alzheimer's.

19 Mar 2012

GABA neurons could help restore muscle coordination deficits of Huntington's

Huntington's disease, the debilitating congenital neurological disorder that progressively robs patients of muscle coordination and cognitive ability, is a condition without effective treatment, a slow death sentence. But if researchers can build on new research reported this week in the journal Cell Stem Cell, a special type of brain cell forged from stem cells could help restore the muscle coordination deficits that cause the uncontrollable spasms characteristic of the disease.

16 Mar 2012

Measuring wellbeing in Huntington’s disease

The new tool, the first Huntington’s disease-specific quality of life instrument of its kind, aims to fully capture the impact of this complex disease on the everyday life of sufferers. By using this new tool to more accurately measure the impact of Huntington’s and also any effect of therapeutic interventions, scientists will be in a better position to evaluate the usefulness of interventions on patients’ everyday quality of life to see if there is actually a practical benefit. It is hoped that in this way, this tool will lead to more effective treatments.

8 Mar 2012

Nuvilex overcomes fundamental challenges faced in stem cell therapy

Nuvilex, Inc., an emerging biotechnology provider of cell and gene therapy solutions, released information today about the company's cell encapsulation technology and the breakthrough in stem cell research which overcomes specific fundamental challenges faced in stem cell therapy—host rejection and migration of implanted cells away from the target site.

5 Mar 2012

WUSTL scientists to decode DNA of 99 patients with rare diseases

Rare genetic diseases, long overlooked because they affect relatively few people, are getting new attention. Scientists at Washington University School of Medicine in St. Louis are reaching out to patient advocacy groups and offering to decode the DNA of 99 patients with rare diseases to help find the genetic alterations responsible for their illnesses.

3 Mar 2012

Researchers refute widely accepted hypothesis about causative step in ALS

In science, refuting a hypothesis can be as significant as proving one, all the more so in research aimed at elucidating how diseases proceed with a view toward preventing, treating, or curing them. Such a discovery can save scientists from spending precious years of effort exploring a dead end. In a study published in the Proceedings of the National Academy of Sciences, Munich-based researchers refute a widely accepted hypothesis about a causative step in neurodegenerative conditions.

1 Mar 2012

Researchers discover mechanism by which lead alters nerve cells in the brain

Exposure to lead wreaks havoc in the brain, with consequences that include lower IQ and reduced potential for learning. But the precise mechanism by which lead alters nerve cells in the brain has largely remained unknown.

1 Mar 2012

Gallup-Healthways WBI data shows decline in the U.S. obesity rates

Adult obesity in America has plateaued and may be slowly declining, according to data from The Gallup-Healthways Well-Being Index (WBI) presented today at the Population Health and Care Coordination Colloquium in Philadelphia. The obesity rate in America fell in 2011 to 26.1 percent, from 26.6 percent in 2010 and 26.5 percent in 2009.

27 Feb 2012

Helmholtz Association grant for research on diseases caused by protein misfolding

Professor Erich Wanker of the Max Delbr-ck Center for Molecular Medicine (MDC) Berlin-Buch and of the Excellence Cluster Neurocure is to receive EUR 675 000 in funding from the Helmholtz Association over the next two years. The grant shall be used to accelerate the search for active agents to treat diseases that are caused by protein misfolding. These include Alzheimer's and Parkinson's.

24 Feb 2012

New drug for Huntington's disease might operate via previously unknown mechanisms of action

A study from Karolinska Institutet in Sweden shows that a new drug for Huntington's disease - pridopidine or dopamine stabiliser ACR16 - might operate via previously unknown mechanisms of action. Researchers have found that at very low concentrations, ACR16 binds to the sigma-1 receptor, a protein in the brain important to neuronal function and survival.

24 Feb 2012

New Huntington's drug might operate via previously unknown mechanisms of action

24 Feb 2012

INFORMS Conference on Business Analytics & Operations Research to take place in April

Analytics, the increasingly important specialty that has been cited by Harvard Business Review, Sloan Management Review, Gartner, and Accenture for aiding better decisions at organizations, will be the focus of a conference hosted by the Institute for Operations Research and the Management Sciences (INFORMS-), the premier organization for advanced analytics professionals.

23 Feb 2012

AChemS recognizes Monell Center molecular biologist as outstanding junior scientist

Molecular biologist Ichiro Matsumoto, Ph.D., of the Monell Center, is the recipient of the 2012 Ajinomoto Award for Young Investigators in Gustation, awarded annually by the Association for Chemoreception Sciences (AChemS) to an outstanding junior scientist who is an emerging leader in the field of gustation.

22 Feb 2012

Huntington’s Disease News and Research

House Republicans divided over how to 'replace' health law

Couples with infertility and miscarriages offered detailed embryo screening with 99% accuracy

Researchers examines whether MRI can improve accuracy of Huntington’s diagnosis

Researchers identify gene that increases risk of MI in newborns with CF

Huntington’s disease may protect against cancer: Study

Nmnat enzyme plays a critical role in nerve injury

Technique developed to identify rogue clustering proteins in brain diseases

Novel technique rapidly identifies and tracks location of diseased proteins inside cells

GABA neurons could help restore muscle coordination deficits of Huntington's

Measuring wellbeing in Huntington’s disease

Nuvilex overcomes fundamental challenges faced in stem cell therapy

WUSTL scientists to decode DNA of 99 patients with rare diseases

Researchers refute widely accepted hypothesis about causative step in ALS

Researchers discover mechanism by which lead alters nerve cells in the brain

Gallup-Healthways WBI data shows decline in the U.S. obesity rates

Helmholtz Association grant for research on diseases caused by protein misfolding

New drug for Huntington's disease might operate via previously unknown mechanisms of action

New Huntington's drug might operate via previously unknown mechanisms of action

INFORMS Conference on Business Analytics & Operations Research to take place in April

AChemS recognizes Monell Center molecular biologist as outstanding junior scientist

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