Immunosuppression News and Research

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Immunosuppression involves an act that reduces the activation or efficacy of the immune system. Some portions of the immune system itself have immuno-suppressive effects on other parts of the immune system, and immunosuppression may occur as an adverse reaction to treatment of other conditions.

New resource-based approach to improve HIV care in low- and middle-income countries

A practical resource-based public health approach for the rapid initiation of antiretroviral therapy in HIV-infected individuals living in low- and middle-income countries could save thousands of lives, according to an Essay published January 15 in the open-access journal PLOS Medicine by Mark Tenforde of the University of Washington School of Medicine, and colleagues.

18 Jan 2019

Genetic testing can help personalize diagnosis and treatment of kidney disease, study shows

A new study has found that genes cause about 1 in 10 cases of chronic kidney disease in adults, and identifying the responsible gene has a direct impact on treatment for most of these patients.

26 Dec 2018

Researchers reveal how key transcription factor keeps the immune system in check

Our immune systems defend our bodies against dangerous invaders and help clean up when damage is done. But if our bold protectors are left unsupervised, they sometimes do their jobs too well and end up harming healthy tissues.

17 Dec 2018

Scientists discover cellular mechanism that triggers pneumonia in humans

The situation is relatively common, especially in winter. You come down with the flu, which lasts longer than usual. A few days later, you discover you have pneumonia.

10 Dec 2018

The Lancet study: First baby born following uterus transplantation from deceased donor

Currently, uterus donation is only available for women with family members who are willing to donate. With live donors in short supply, the new technique might help to increase availability and give more women the option of pregnancy.

5 Dec 2018

Study points toward new strategies for managing organ transplantation

The human intestine may provide up to 10 percent of blood cells in circulation from its own reservoir of blood-forming stem cells, a surprising new study from researchers at Columbia University Vagelos College of Physicians and Surgeons has found.

30 Nov 2018

New method could improve outcome of leukemia patients receiving stem-cell transplants

Stem-cell transplantation is an effective form of therapy to fight leukemia. In many cases, however, the transferred immune cells of the donor also attack the recipients' healthy tissue - often with fatal consequences.

28 Nov 2018

Regenerative medicine scientist receives $1.3 million to study stem cell therapy for liver failure

Currently, the only therapy for metabolic liver disease is an organ transplant. Tracy Grikscheit, MD, an attending physician and regenerative medicine scientist at Children's Hospital Los Angeles, hopes to change that reality.

7 Nov 2018

New method to block immunosuppression in cancer discovered

Belgian research groups from the UCLouvain and WELBIO, VIB and Ghent University, and the biotechnology company argenx elucidated the three-dimensional structure of an assembly of proteins operating on cells that dampen immune responses

26 Oct 2018

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Seattle Genetics, Inc. and Takeda Pharmaceutical Company Limited announced today that the phase 3 ECHELON-2 clinical trial met its primary endpoint.

1 Oct 2018

New combination therapy shows potential in treating incurable HPV-related cancers

A tumor-specific vaccine combined with an immune checkpoint inhibitor shrank tumors in one third of patients with incurable cancer related to the human papilloma virus (HPV) in a phase II clinical trial led by investigators at The University of Texas MD Anderson Cancer Center and reported in JAMA Oncology.

28 Sep 2018

ADCETRIS drug receives approval in Japan as frontline treatment option for Hodgkin lymphoma

Seattle Genetics, Inc. today announced that its collaborator, Takeda Pharmaceutical Company Limited, has received approval from the Japanese Ministry of Health, Labour and Welfare for ADCETRIS (brentuximab vedotin) in combination with doxorubicin, vinblastine and dacarbazine as a frontline treatment option for CD30-positive Hodgkin lymphoma patients in Japan.

24 Sep 2018

Immunosuppression News and Research

Further Reading

New resource-based approach to improve HIV care in low- and middle-income countries

Genetic testing can help personalize diagnosis and treatment of kidney disease, study shows

Researchers reveal how key transcription factor keeps the immune system in check

Scientists discover cellular mechanism that triggers pneumonia in humans

The Lancet study: First baby born following uterus transplantation from deceased donor

Study points toward new strategies for managing organ transplantation

New method could improve outcome of leukemia patients receiving stem-cell transplants

Regenerative medicine scientist receives $1.3 million to study stem cell therapy for liver failure

New method to block immunosuppression in cancer discovered

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

New combination therapy shows potential in treating incurable HPV-related cancers

ADCETRIS drug receives approval in Japan as frontline treatment option for Hodgkin lymphoma

Groundbreaking CURATE.AI platform halts progression of advanced cancer

NUS researchers harness AI platform to treat patient with advanced cancer

New minimally invasive therapy shows promise for long-term reversal of Type 1 diabetes

Scientists discover gene that predicts arthritis severity

Scientists support viability of potential way to reduce Alzheimer's disease risk

New clues may lead to rapid detection of sepsis

Scoring system based on PIRO helps predict mortality in surgical ICU patients with severe sepsis

Customising T-cells for cancer immunotherapy

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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