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Researchers develop novel tool to assess fertility knowledge and concerns in transgender youth

A novel tool developed by researchers at Children's National Health System-with critical input from transgender youth and their parents-assesses the level of interest or concern these teens and their families have regarding the impacts of medical gender treatments on long-term fertility.

23 Oct 2017

ACS recognizes contributions of five surgeons with Surgical Humanitarian and Volunteerism Awards

Last night, five surgeons received the 2017 American College of Surgeons/Pfizer Surgical Humanitarian Awards and Surgical Volunteerism Awards in recognition of their selfless efforts as volunteer surgeons who provide care to medically underserved patients abroad.

23 Oct 2017

Timing is crucial for corticosteroids to aid healing of tendons

A corticosteroid can improve the healing of damaged tendons, but it must be given at the right time, according to a new study from Linköping University in Sweden. In rats, the tendon became twice as strong. The results are presented in the journal Scientific Reports.

17 Oct 2017

Study provides insights into potential causes of spinal stenosis

A new study published in the Journal of Orthopaedic Research indicates that certain genetic changes are linked with an increased risk of developing lumbar spinal stenosis, a narrowing of the open spaces in the lower spine that can lead to pain in the legs when individuals walk.

13 Oct 2017

Existing drugs could help patients with rare form of bone cancer

Patients with a rare bone cancer of the skull and spine - chordoma - could be helped by existing drugs, suggest scientists from the Wellcome Trust Sanger Institute, University College London Cancer Institute and the Royal National Orthopaedic Hospital NHS Trust.

12 Oct 2017

New insights into rare-among-rare genetic bone disorder

I have been writing about conditions that cause out-of-place bone formation for over 10 years – since the discovery of the gene in 2006 for the rare bone disorder, FOP (fibrodysplasia ossificans progressive). But it was while interviewing geneticist Eileen Shore, PhD last spring about another bone disorder, progressive osseous heteroplasia, or POH, that it really hit me how much more rare POH is compared to FOP.

10 Oct 2017

Study sheds light on complex process involved in development of sperm stem cells

New research from scientists at Huntsman Cancer Institute at the University of Utah and collaborators at University of Utah Health sheds light on the complex process that occurs in the development of human sperm stem cells.

5 Oct 2017

Treating cartilage grafts with bone marrow concentrate before joint replacement speeds recovery

Biologic joint restoration using donor tissue instead of traditional metal and plastic may be an option for active patients with joint defects. Although recovery from a biologic joint repair is typically longer than traditional replacement, successful biologic restoration allows patients to return to full activity. However, in some cases, the transplanted bone does not heal correctly.

25 Sep 2017

Study findings offer refined approach to predict risk of ARMD in patients with MoM hip implants

Patients with "metal on metal" (MoM) artificial hips are at risk of complications caused by adverse reactions to metal debris (ARMD). A study in the September 20, 2017 issue of The Journal of Bone & Joint Surgery confirms that blood metal ion levels specific to the type of hip implant used can help predict patients who are at low risk of ARMD.

21 Sep 2017

MIT engineers design more effective synthetic mRNA delivery system

By delivering strands of genetic material known as messenger RNA into cells, researchers can induce the cells to produce any protein encoded by the mRNA. This technique holds great potential for administering vaccines or treating diseases such as cancer, but achieving efficient delivery of mRNA has proven challenging.

21 Sep 2017

Researchers explore new combination approach to treat high-risk soft-tissue sarcomas

University of Maryland School of Medicine researchers are investigating a new approach to treat high-risk soft-tissue sarcomas by combining two immunotherapy drugs with radiation therapy to stimulate the immune system to destroy the main tumor as well as leftover microscopic cancer cells that may seed other tumors.

20 Sep 2017

‘Nanokicking’ technology allows scientists to grow 3D mineralized bone tissue

Researchers from the Universities of Glasgow, Strathclyde, the West of Scotland and Galway have grown three-dimensional samples of mineralized bone from human mesenchymal stem cells for the first time without typical osteoinductive media.

15 Sep 2017

Harmonic Drive describe surgical robots and their potential

Medical robots, a technology once considered the realm of science fiction and the figment of an overzealous imagination, are now a reality. The industry is worth billions already and growing rapidly. Here, Graham Mackrell, managing director of high precision gearing specialist, Harmonic Drive UK, explores the latest trends in the field.

15 Sep 2017

Research finds link between caregiver’s gender, relationship and severity of child abuse injuries

Efforts to prevent child abuse by people who care for children should extend to additional categories of caregivers since injuries that children suffer at the hands of their parent's male partner, babysitter or daycare worker are likely to be more severe, according to research presented during the 2017 American Academy of Pediatrics national conference.

15 Sep 2017

Research highlights problems with titanium based nanoparticles in joint implants

A team of researchers from Mayo Clinic have found that that Titanium Dioxide (TiO2) nanoparticles that are present in bone implants may be causing harm by impairing bone formation and interfering with resorption at the site of repair. This can lead to loosening of the implants and pain.

15 Sep 2017

Penn researchers find abnormally shortened telomeres in young DMD patients’ muscle stem cells

Researchers from the Perelman School of Medicine at the University of Pennsylvania have made a discovery about muscular dystrophy disorders that suggest new possibilities for treatment.

7 Sep 2017

Researchers find correlation between shorter telomeres and presence of heart failure

Each cell in the average human body contains 23 pairs of chromosomes, with four telomeres on each pair. Telomeres cover the end of the chromosome, protecting it from deterioration or fusion with adjacent chromosomes, much like the plastic tip at the end of a shoelace protects it from unraveling.

7 Sep 2017

Orthopaedic News and Research

Researchers develop novel tool to assess fertility knowledge and concerns in transgender youth

ACS recognizes contributions of five surgeons with Surgical Humanitarian and Volunteerism Awards

Timing is crucial for corticosteroids to aid healing of tendons

Study provides insights into potential causes of spinal stenosis

Existing drugs could help patients with rare form of bone cancer

New insights into rare-among-rare genetic bone disorder

Study sheds light on complex process involved in development of sperm stem cells

Treating cartilage grafts with bone marrow concentrate before joint replacement speeds recovery

Study findings offer refined approach to predict risk of ARMD in patients with MoM hip implants

MIT engineers design more effective synthetic mRNA delivery system

Researchers explore new combination approach to treat high-risk soft-tissue sarcomas

‘Nanokicking’ technology allows scientists to grow 3D mineralized bone tissue

Harmonic Drive describe surgical robots and their potential

Research finds link between caregiver’s gender, relationship and severity of child abuse injuries

Research highlights problems with titanium based nanoparticles in joint implants

Penn researchers find abnormally shortened telomeres in young DMD patients’ muscle stem cells

Researchers find correlation between shorter telomeres and presence of heart failure

Research on electrical nerve-block implant aims at treating asthma and heart failure

Research may lead to first-ever pharmacological treatment for rare genetic bone disease

Tiny tears in membranes of bone cells may be key to strong bones

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The role of UV-Vis in biopharma QC

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