Orthopaedic News and Research

RSS

Experts endorse recommendations for restrictive blood transfusions

By analyzing data from randomized clinical trials comparing blood transfusion approaches, Johns Hopkins experts, along with colleagues at Cleveland Clinic and NYU Langone Medical Center, endorse recommendations for blood transfusions that reduce blood use to improve patient safety and outcomes.

20 Nov 2017

Orthocell earns CE Mark approval for CelGro collagen medical device

Regenerative medicine company Orthocell Limited is pleased to announce receipt of European regulatory approval (CE Mark) for its CelGro collagen medical device.

8 Nov 2017

Study findings could help reduce unnecessary testing in children with postoperative fever

Despite a low likelihood of positive results, children who develop fever in the first two days after surgery are often subjected to non-targeted, costly and invasive testing. This is according to a study that was recently published in the Journal of Pediatric Surgery.

8 Nov 2017

Many patients with knee, hip and spine osteoarthritis use opioids to manage chronic pain

A large percentage of patients with end-stage knee, hip and spine osteoarthritis use opioids to manage their chronic pain, especially those who are younger or have symptoms of depression, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

6 Nov 2017

New study shows effects of obesity on knee dislocations

A new study of more than 19,000 knee dislocation cases in the U.S. between 2000 and 2012 provides a painful indication of how the nation's obesity epidemic is changing the risk, severity, and cost of a traumatic injury.

3 Nov 2017

Report reveals high risk of back, shoulder and other injuries for competitive divers

Competitive divers face a high risk of injuring their shoulders, back, elbows, wrists and other body parts, according to a report by a Loyola Medicine sports medicine physician.

30 Oct 2017

Reverse shoulder replacement provides lasting improvement for younger patients

For younger patients with severe damage to the rotator cuff muscles, a "reverse" shoulder replacement provides lasting improvement in shoulder function, according to a study in The Journal of Bone & Joint Surgery.

26 Oct 2017

Study identifies protein that plays crucial role in diabetic retinopathy

For millions of Americans, their world is dissolving into an unrecognizable blur. Diabetic retinopathy is an eye disease affecting one-third of the estimated 30 million Americans who struggle with diabetes. As the patients' vision slowly fades, it never recovers and few treatments are available.

24 Oct 2017

Researchers develop novel tool to assess fertility knowledge and concerns in transgender youth

A novel tool developed by researchers at Children's National Health System-with critical input from transgender youth and their parents-assesses the level of interest or concern these teens and their families have regarding the impacts of medical gender treatments on long-term fertility.

23 Oct 2017

ACS recognizes contributions of five surgeons with Surgical Humanitarian and Volunteerism Awards

Last night, five surgeons received the 2017 American College of Surgeons/Pfizer Surgical Humanitarian Awards and Surgical Volunteerism Awards in recognition of their selfless efforts as volunteer surgeons who provide care to medically underserved patients abroad.

23 Oct 2017

Timing is crucial for corticosteroids to aid healing of tendons

A corticosteroid can improve the healing of damaged tendons, but it must be given at the right time, according to a new study from Linköping University in Sweden. In rats, the tendon became twice as strong. The results are presented in the journal Scientific Reports.

17 Oct 2017

Study provides insights into potential causes of spinal stenosis

A new study published in the Journal of Orthopaedic Research indicates that certain genetic changes are linked with an increased risk of developing lumbar spinal stenosis, a narrowing of the open spaces in the lower spine that can lead to pain in the legs when individuals walk.

13 Oct 2017

Existing drugs could help patients with rare form of bone cancer

Patients with a rare bone cancer of the skull and spine - chordoma - could be helped by existing drugs, suggest scientists from the Wellcome Trust Sanger Institute, University College London Cancer Institute and the Royal National Orthopaedic Hospital NHS Trust.

12 Oct 2017

New insights into rare-among-rare genetic bone disorder

I have been writing about conditions that cause out-of-place bone formation for over 10 years – since the discovery of the gene in 2006 for the rare bone disorder, FOP (fibrodysplasia ossificans progressive). But it was while interviewing geneticist Eileen Shore, PhD last spring about another bone disorder, progressive osseous heteroplasia, or POH, that it really hit me how much more rare POH is compared to FOP.

10 Oct 2017

Study sheds light on complex process involved in development of sperm stem cells

New research from scientists at Huntsman Cancer Institute at the University of Utah and collaborators at University of Utah Health sheds light on the complex process that occurs in the development of human sperm stem cells.

5 Oct 2017

Treating cartilage grafts with bone marrow concentrate before joint replacement speeds recovery

Biologic joint restoration using donor tissue instead of traditional metal and plastic may be an option for active patients with joint defects. Although recovery from a biologic joint repair is typically longer than traditional replacement, successful biologic restoration allows patients to return to full activity. However, in some cases, the transplanted bone does not heal correctly.

25 Sep 2017

Study findings offer refined approach to predict risk of ARMD in patients with MoM hip implants

Patients with "metal on metal" (MoM) artificial hips are at risk of complications caused by adverse reactions to metal debris (ARMD). A study in the September 20, 2017 issue of The Journal of Bone & Joint Surgery confirms that blood metal ion levels specific to the type of hip implant used can help predict patients who are at low risk of ARMD.

21 Sep 2017

MIT engineers design more effective synthetic mRNA delivery system

By delivering strands of genetic material known as messenger RNA into cells, researchers can induce the cells to produce any protein encoded by the mRNA. This technique holds great potential for administering vaccines or treating diseases such as cancer, but achieving efficient delivery of mRNA has proven challenging.

21 Sep 2017

Researchers explore new combination approach to treat high-risk soft-tissue sarcomas

University of Maryland School of Medicine researchers are investigating a new approach to treat high-risk soft-tissue sarcomas by combining two immunotherapy drugs with radiation therapy to stimulate the immune system to destroy the main tumor as well as leftover microscopic cancer cells that may seed other tumors.

20 Sep 2017

‘Nanokicking’ technology allows scientists to grow 3D mineralized bone tissue

Researchers from the Universities of Glasgow, Strathclyde, the West of Scotland and Galway have grown three-dimensional samples of mineralized bone from human mesenchymal stem cells for the first time without typical osteoinductive media.

15 Sep 2017