Peripheral Artery Disease News and Research

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Peripheral arterial disease (PAD) occurs when leg arteries become narrowed or blocked by plaque. These blockages can result in severe pain for patients, limited physical mobility, and life-threatening non-healing leg ulcers. According to the American Heart Association, this condition affects approximately 8 to 12 million Americans. With only about 25 percent of PAD patients undergoing treatment, it is a disease that is largely under-diagnosed and under-treated. If left untreated, PAD can lead to critical leg ischemia, a condition where not enough blood is being delivered to the leg to keep the tissue alive. Total loss of circulation to the legs and feet can cause gangrene and lead to amputation.

Almost half of elderly Beijing residents have metabolic syndrome

As more people in China adopt Western diets and lifestyles, many are developing a cluster of cardiovascular disease risk factors, according to a new study in the April 18, 2006, issue of the Journal of the American College of Cardiology.

17 Apr 2006

Division of the penile suspensory ligament often leads to less than satisfactory results in augmentation phalloplasty

Division of the penile suspensory ligament with or without the additional procedures of suprapubic fat pad excision and inverted VY plasty is a simple and commonly used penile lengthening technique. A recent study by C. Y. Li and colleagues from London examined patient satisfaction with penile suspensory ligament division for penile augmentation.

5 Apr 2006

Radical prostatectomy QoL outcomes can be obtained in single-surgeon practices

Most often urologists cite radical prostatectomy (RP) outcomes from large studies and high volume centers. However, these may not accurately reflect the outcomes of individual surgeons.

30 Mar 2006

Study provides a boost for efforts to reverse type-1 diabetes

Researchers have been able to confirm most but not all of the results of a high-profile study that brought new hope to diabetes patients. This study provides a boost for efforts to reverse type-1 diabetes in recently diagnosed patients but not for efforts to grow new islets from spleens.

27 Mar 2006

Innovative treatment for critical limb ischemia

A new randomized study presented at the American College of Cardiology's 55th Annual Scientific Session investigates an innovative treatment for critical limb ischemia, or lack of arterial blood supply and oxygen to the legs, using a therapeutic approach to generate new blood vessels.

14 Mar 2006

Using a growth factor to stimulate production of circulating endothelial progenitor cells improves cell production and mobility in arterial disease

Using a growth factor to stimulate production of circulating endothelial progenitor cells increases the numbers of these vascular regenerative cells, improves mobility, and potentially could improve blood vessel function in patients with peripheral arterial disease (PAD).

13 Mar 2006

Stem cell injections may help those with severe peripheral artery disease

Indiana University School of Medicine scientists have begun a unique clinical trial using stem cell injections as a treatment that could offer hope to tens of thousands of people who face sores, ulcers and even amputations due to severe peripheral artery disease.

14 Feb 2006

Phase II clinical trial for new gene transfer drug study

As many as 8-10 million Americans have Peripheral Artery Disease (PAD), by age 70, roughly 20 percent of the population has it, and people with PAD face a six-to-seven times higher risk of heart attack or stroke.

2 Feb 2006

Innovative approach to cartilage repair

Leeds bioengineers have developed an innovative technique for cartilage repair combining the self-healing powers of the body with stem cell science to help young people avoid debilitating knee problems and give hope to arthritis sufferers.

2 Feb 2006

Walking slows progression of peripheral artery disease

A study in the Annals of Internal Medicine shows that walking three times a week, even in an unsupervised exercise program, can significantly improve walking ability and slow progression of peripheral artery disease (PAD). PAD often causes leg pain because of impaired blood flow in the arteries.

8 Jan 2006

3 walks a week can slow the progression of peripheral artery disease

A study in the Jan. 3 issue of the Annals of Internal Medicine shows that walking three times a week, even in an unsupervised exercise program, can significantly improve walking ability and slow progression of peripheral artery disease (PAD). PAD often causes leg pain because of impaired blood flow in the arteries.

2 Jan 2006

Heart disease risk higher if a brother or sister has heart problems

According to a new report having a brother or sister with a cardiovascular disease poses a greater risk than having a parent with a history of the disease.

28 Dec 2005

Cancer road map shows how cancer spreads

Scientists at Cornell University in New York have discovered how cancer spreads from a primary site to other places in the body.

11 Dec 2005

Subclinical hypothyroidism associated with increased risk of congestive heart failure

A hormonal condition known as subclinical hypothyroidism is associated with an increased risk of congestive heart failure among older adults, but not with other cardiovascular events and death, according to a study in the November 28 issue of Archives of Internal Medicine.

7 Dec 2005

Under-active thyroid can increase heart failure risk

According to a new study older adults people who have an under active thyroid, or hypothyroidism, but with no symptoms, have an increased the risk of congestive heart failure.

30 Nov 2005

Lack of aggressive treatment for clogged leg blood vessels means missed heart attack prevention opportunity

Despite the fact that clogged arteries in the legs usually mean clogged arteries near the heart, doctors often fail to give heart-protecting drugs to people with severe leg blood vessel blockages, a new University of Michigan-led study finds.

15 Nov 2005

Magnetic shoe insoles did not effectively relieve foot pain

...researchers report in the current issue of Mayo Clinic Proceedings. And the results indicate that patients who strongly believed in magnets had pain relief even if they were given false magnets to wear.

26 Sep 2005

Legs For Life free national screening program can save legs

The screening is essential for diabetics in order to prevent amputation, heart attack and stroke, because one-third have PAD, but most do not present classic symptoms.

1 Sep 2005

Study focuses on peripheral arterial disease - availability of vascular surgeons impacts amputation rate

Patients with peripheral arterial disease (PAD) are more likely to have a foot or leg amputated if they live in a region that has few vascular surgeons, according to a Rice University/Baylor College of Medicine study published in the July issue of the Journal of Vascular Surgery.

12 Jul 2005

Trial to evaluate modern stent technologies over balloon angioplasty for peripheral arterial disease

The first patient undergoes treatment today in a new prospective randomised trial, called the SUPER Study, to compare stenting with balloon angioplasty in patients with superficial femoral artery (SFA) occlusions caused by peripheral artery disease (PAD).

28 Apr 2005