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Prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection

Researchers assess the impact of COVID-19 vaccination on immune responses during a breakthrough infection.

9 Feb 2023

Heterologous inactivated virus/mRNA booster strongly augments response to BF.7, BQ.1.1, and XBB.1

Heterologous vaccination improves the neutralization of SARS-CoV-2 Omicron sub-variants.

9 Feb 2023

Researcher contextualizes a study on IgG4 anti-Spike levels after repeated SARS-CoV-2 mRNA vaccination

A researchers emphasized the need to reconsider mRNA COVID-19 vaccination strategies in the future,

9 Feb 2023

A microbiota-driven mechanism underlies severity of leishmaniasis infection

In a recent study posed to the medRxiv* preprint server, researchers in Brazil and the United States investigated the probable impact of the skin microbiome microbiota on the outcomes of cutaneous leishmaniasis.

8 Feb 2023

Macrophages suppress Escherichia coli LF82 Gally prophage lytic cycle

Researchers analyze prophages of the LF82 strain of adherent-invasive Escherichia coli to better understand their behavior in vitro and within macrophages.

8 Feb 2023

Recent findings on T-cell immunity induced by SARS-CoV-2 infection and vaccination in immunocompromised individuals

Researchers discussed studies that explored T-cell immunity induced by SARS-CoV-2 infection and COVID-19 vaccination in cancer patients, individuals with HIV, and recipients of solid organ transplants.

8 Feb 2023

Study shows activation of pulmonary macrophages by SARS-CoV-2 spike glycoprotein

In a recent study published in the International Journal of Molecular Sciences, researchers investigated the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein on human lung macrophage (HLM) activation and angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) expression in human lung macrophages.

7 Feb 2023

Bivalent boosters provide additional protection from BA.5, XBB, and XBB.1.5

In a recent Morbidity and Mortality Weekly Report (MMWR) published on the United States Center for Disease Control and Prevention (US-CDC) website, researchers analyzed data from the Increasing Community Access to Testing (ICATT), a nationwide pharmacy program run in the US for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing.

7 Feb 2023

Mucoactive drugs block SARS-CoV-2 infection

Researchers evaluate the effects of mucociliary active molecules on SARS-CoV-2 infection in vitro.

7 Feb 2023

Symptomatic SARS-CoV-2 infection during pregnancy increases risk of complications for mother and infant

Researchers investigate the obstetric and neonatal outcomes in unvaccinated pregnant females infected with the SARS-CoV-2.

7 Feb 2023

Cardiovascular risk in psoriasis, the association between psoriatic inflammation and atherosclerosis, and the cardiovascular-risk-reducing effects of biologics

Researchers explored the impact of biological interventions in reducing cardiovascular risk among psoriasis patients.

6 Feb 2023

Study suggests that both mother and infant can contribute to the human milk microbiome

Researchers examined associations between the bacterial composition of human milk and maternal and infant factors.

6 Feb 2023

SARS-CoV-2 infections on French mink farms after one year of COVID-19

A new paper, which appears on the bioRxiv* preprint server, describes the investigation of all French mink farms towards the end of 2020. This was to maximize the chances of identifying SARS-CoV-2 infection in these animals at any time over the past year.

3 Feb 2023

The relationship between natural plant extracts and SARS-CoV-2

Researchers explored plants as an extensive resource of molecules with potential therapeutic action against SARS-CoV-2 and debunked misconceptions.

3 Feb 2023

Molnupiravir-related mutational signatures among COVID-19 patients

Researchers explore a mutational signature related to molnupiravir in SARS-CoV-2 sequencing datasets.

3 Feb 2023

Researchers report a heterologous vaccination strategy against IBV in Chickens

Researchers reported on the immunogenicity of a heterologous vaccine regimen against IBV, comprising prime doses of QAC-encapsulated plasmid and a booster dose of MVA.

2 Feb 2023

Breakthrough Omicron BA.1/BA.2 infections in the triple-vaccinated linked to broad-based immunity

A new study looked at the whole spectrum of immunological reactions raised by spike and non-spike antigens following Omicron BA.1/BA.2 infections in such individuals, both with and without prior SARS-CoV-2 infection.

1 Feb 2023

Risk factors for Omicron reinfections among previously infected frontline workers in the United States

Researchers examined a prospective cohort of frontline workers in the United States (US) previously infected with SARS-CoV-2. They attempted to identify risk factors that made this highly vulnerable population prone to reinfection by SARS-CoV-2 new variant of concern (VOC), Omicron, known for its high immune evading potential.

1 Feb 2023

Transcriptomics analysis identifies thousands of viroid-like circular RNA molecules

Metatranscriptomics analysis reveals the existence of over ten thousand viroids and viroid-like RNAs.

1 Feb 2023

Study demonstrates intrahost MPXV variation within a single lesion

Researchers reported on the clinical and molecular characteristics of MPXV infections in Finland.

31 Jan 2023

Ribonucleic Acid News and Research

Prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection

Heterologous inactivated virus/mRNA booster strongly augments response to BF.7, BQ.1.1, and XBB.1

Researcher contextualizes a study on IgG4 anti-Spike levels after repeated SARS-CoV-2 mRNA vaccination

A microbiota-driven mechanism underlies severity of leishmaniasis infection

Macrophages suppress Escherichia coli LF82 Gally prophage lytic cycle

Recent findings on T-cell immunity induced by SARS-CoV-2 infection and vaccination in immunocompromised individuals

Study shows activation of pulmonary macrophages by SARS-CoV-2 spike glycoprotein

Bivalent boosters provide additional protection from BA.5, XBB, and XBB.1.5

Mucoactive drugs block SARS-CoV-2 infection

Symptomatic SARS-CoV-2 infection during pregnancy increases risk of complications for mother and infant

Cardiovascular risk in psoriasis, the association between psoriatic inflammation and atherosclerosis, and the cardiovascular-risk-reducing effects of biologics

Study suggests that both mother and infant can contribute to the human milk microbiome

SARS-CoV-2 infections on French mink farms after one year of COVID-19

The relationship between natural plant extracts and SARS-CoV-2

Molnupiravir-related mutational signatures among COVID-19 patients

Researchers report a heterologous vaccination strategy against IBV in Chickens

Breakthrough Omicron BA.1/BA.2 infections in the triple-vaccinated linked to broad-based immunity

Risk factors for Omicron reinfections among previously infected frontline workers in the United States

Transcriptomics analysis identifies thousands of viroid-like circular RNA molecules

Study demonstrates intrahost MPXV variation within a single lesion

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