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Study demonstrates successful gene therapy for maple syrup urine disease

A study led by UMass Chan researchers demonstrated that a gene therapy to correct a mutation that causes maple syrup urine disease (MSUD) prevented newborn death, normalized growth, restored coordinated expression of the affected genes and stabilized biomarkers in a calf as well as in mice.

28 Feb 2025

New chemical reaction enables precise functionalization of peptides and proteins

Pharmaceutical scientists at the National University of Singapore (NUS) have developed a novel chemical reaction that enables the precise functionalization of peptides and proteins.

28 Feb 2025

Lactylation in the heart reveals key insights into cardiac regeneration

This study is led by Dr. Xiaodong Luan (Institute of Clinical Medicine, Peking Union Medical College Hospital), Dr. Shuyang Zhang (Department of Rare Diseases, Peking Union Medical College Hospital) and Dr. He Huang (Shanghai Institute of Materia Medica, Chinese Academy of Sciences).

28 Feb 2025

European project aims to develop new treatments for rare eye diseases

The Ocular Neurobiology laboratory at the Institute for Neurosciences, a joint center of Miguel Hernández University (UMH) in Elche and the Spanish National Research Council (CSIC), is participating in the European project RESTORE VISION, an ambitious initiative aimed at developing new treatments for rare eye diseases such as aniridia and neurotrophic keratopathy.

28 Feb 2025

Review sheds light on the mechanistic role of long non-coding RNAs in liver disease

Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), is a global health challenge, affecting nearly 30% of adults worldwide.

28 Feb 2025

Researchers make breakthrough in understanding the role of tau protein in Alzheimer's

A research team at the University of Cologne has made a significant breakthrough in understanding the role of the tau protein in Alzheimer's disease.

28 Feb 2025

Understanding the impact of SLC transporters on liver disease progression

Hepatic steatosis, often triggered by non-alcoholic fatty liver disease (NAFLD), is a leading cause of liver dysfunction globally, affecting approximately 30% of the population.

28 Feb 2025

First-ever clinical trials evaluate fenofibrate as treatment for HPV-related cancers

A team from University Hospitals Seidman Cancer Center is launching the nation's first-ever clinical trials evaluating the cholesterol drug fenofibrate (Triglide, Fibricor, Lipofen) as an investigational and potential treatment for patients with HPV+ cervical and HPV+ head and neck cancer (HNSCC).

28 Feb 2025

Atlantia Clinical Trials: Investigating the interrelation of microbiology and immunology

Atlantia Clinical Trials investigates the role of microbiomes in immunity, focusing on gut and lung interactions to develop innovative health solutions.

From Atlantia Clinical Trials 28 Feb 2025

Future of cancer coverage for women federal firefighters uncertain under Trump

It took nearly three years to win presumptive workers' compensation coverage for breast, cervical, and other cancers that firefighters who work for federal agencies may develop because of hazardous exposures on the job.

28 Feb 2025

New discovery sheds light on energy crisis in children with TANGO2 deficiency

Researchers studying a protein linked to a rare, severe disease have made a discovery that sheds light on how cells meet their energy needs during a severe metabolic crisis.

28 Feb 2025

Study reveals how air pollution contributes to Alzheimer's disease

Air pollution contributes to nearly 7 million premature deaths each year, and its effects go far beyond the lungs.

28 Feb 2025

UCSF study reveals lungs as source of hematopoietic stem cells

Red blood cells carry oxygen from the lungs to every other organ, and blood-forming stem cells must make about 200 billion new red blood cells each day to keep the oxygen flowing.

28 Feb 2025

Trained immunity may exacerbate inflammatory bone loss disorders

Clinical research has long focused on ways to harness the actions of the immune system. From vaccines to immunotherapies, researchers have used their knowledge of the immune system to develop therapies to treat or prevent diseases from influenza to autoimmune disease and cancer.

27 Feb 2025

Cell News and Research

Study demonstrates successful gene therapy for maple syrup urine disease

New chemical reaction enables precise functionalization of peptides and proteins

Lactylation in the heart reveals key insights into cardiac regeneration

European project aims to develop new treatments for rare eye diseases

Review sheds light on the mechanistic role of long non-coding RNAs in liver disease

Researchers make breakthrough in understanding the role of tau protein in Alzheimer's

Understanding the impact of SLC transporters on liver disease progression

First-ever clinical trials evaluate fenofibrate as treatment for HPV-related cancers

Atlantia Clinical Trials: Investigating the interrelation of microbiology and immunology

Future of cancer coverage for women federal firefighters uncertain under Trump

New discovery sheds light on energy crisis in children with TANGO2 deficiency

Study reveals how air pollution contributes to Alzheimer's disease

UCSF study reveals lungs as source of hematopoietic stem cells

Trained immunity may exacerbate inflammatory bone loss disorders

Investigating genetic differences in Listeria strains used for listeriosis vaccine

New deep-learning framework improves spatial transcriptomics analysis

EU project aims to combat dangerous viruses with molecular interventions

New ASTRO guideline offers radiation therapy recommendations for anal cancer

Vaping while pregnant isn't harmless—study uncovers risks to newborn lung health

Advancements in molecular diagnostics for hematopoietic and lymphocytic neoplasms

Improve fermentation and cell culture performance with real-time gas analysis eBook

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