OCT News and Research

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Optical coherence tomography helps track multiple sclerosis

A five-minute eye exam might prove to be an inexpensive and effective way to gauge and track the debilitating neurological disease multiple sclerosis, potentially complementing costly magnetic resonance imaging to detect brain shrinkage - a characteristic of the disease's progression.

16 Oct 2007

Insomniac fish help understand the genetics behind sleep disorders

Scientists at the Stanford University School of Medicine have hooked a fish that suffers from insomnia in their quest to understand the genetics behind sleep disorders.

16 Oct 2007

HiFi DNA Tech files lawsuit against FDA

A lawsuit was filed Oct. 12 in U.S. District Court against the U.S. Department of Health and Human Services (HHS) and the U.S. Food and Drug Administration (FDA) related to reclassification of HPV DNA tests from class III to class II devices. The inaction by both agencies hinders introduction of new and affordable HPV testing to improve women’s health care.

15 Oct 2007

Important insights into blood vessel formation

Researchers have identified a molecular pathway that plays a critical role in the growth of blood vessels.

15 Oct 2007

Microarray-based genomic selection accelerates discovery of subtle DNA variations

A new technology developed by scientists at Emory University will allow researchers to more easily discover subtle and overlooked genetic variations that may have serious consequences for health and disease.

15 Oct 2007

Breast cancer radiation does not affect women's immune system

A new study shows that neither of two commonly used radiation treatments for early-stage, node-negative breast cancer has any effect on a woman's immune system, even though women who receive five-day partial-breast radiation therapy (MammoSite brachytherapy) (PBRT) have improved energy and quality of life compared to women who undergo six weeks of whole-breast radiation therapy (WBRT).

15 Oct 2007

Six years advance warning of Alzheimer's

One of the most distressing aspects of Alzheimer's disease is the difficulty in determining whether mild memory problems are the beginning of an inevitable mental decline.

15 Oct 2007

Gene SIRT1 could lead to new cholesterol strategies

MIT researchers have discovered a link between a gene believed to promote long lifespan and a pathway that flushes cholesterol from the body. The finding could help researchers create drugs that lower the risk of diseases associated with high cholesterol, including atherosclerosis (clogged arteries) and Alzheimer's disease.

12 Oct 2007

Chlamydomonas reinhardtii genome holds clues for renewable energy, the environment and human health

University of Minnesota researchers contributed to a national effort to sequence the genome of an ancient, one-celled organism that will help advance research in a broad range of areas, from biofuels to restoring the environment to understanding a variety of human diseases.

12 Oct 2007

Recognizing and assessing the progression of cognitive impairment and dementia in primary care

Dementia is a growing burden for society, propelling patients and caregivers to increasingly use the health-care system. A year ago, local researchers, health-care professionals, and community advocates came together to form the Indianapolis Discovery Network for Dementia (IDND) to enhance dementia care in the nation's twelfth largest city.

12 Oct 2007

Anticlotting drug found to be safe in sickle cell patients

An intravenous "blood thinner" widely used in patients with acute coronary syndromes and during coronary artery stent placement appears to be safe in patients with sickle cell disease and may have beneficial anti-inflammatory effects, a small study at the University of North Carolina at Chapel Hill School of Medicine has found.

12 Oct 2007

Analysis of breast and colon cancer genes finds 5,000 previously unmapped genes

Researchers from University Hospitals (UH) Ireland Cancer Center and Case Western Reserve University School of Medicine are part of a new national study that has analyzed more than 18,000 genes, including 5,000 previously unmapped genes, from breast and colorectal tumors.

12 Oct 2007

A fresh perspective to the study of cell activity

In process that is shrouded in mystery, rod-shaped bacteria reproduce by splitting themselves in two. By applying advanced mathematics to laboratory data, a team led by Johns Hopkins researchers has solved a small but important part of this reproductive puzzle.

12 Oct 2007

New understanding of stem cell aging

The Stowers Institute's Xie Lab has published recent findings that reveal some of the factors underlying the aging of stem cells.

11 Oct 2007

Hypoplastic left heart syndrome likely caused by genetic factors

Hypoplastic Left Heart Syndrome (HLHS), a severe cardiovascular malformation that is difficult to treat and often lethal, is caused primarily by genetic factors, according to a new study by researchers at Cincinnati Children's Hospital Medical Center.

11 Oct 2007

Researchers identify brain circuits used in sensation of touch

The ability to tactually recognize fine spatial details, such as the raised dots used in braille, is especially important to those who are blind.

11 Oct 2007

HER-2 status predicts success of chemotherapy in breast cancer treatment

Researchers have found they can potentially target chemotherapy for breast cancer to only those women most likely to benefit, sparing the majority of patients from unnecessary side effects.

10 Oct 2007

Stress is a contributing factor in human disease

In a review of the scientific literature on the relationship between stress and disease, Carnegie Mellon University psychologist Sheldon Cohen has found that stress is a contributing factor in human disease, and in particular depression, cardiovascular disease and HIV/AIDS.

10 Oct 2007

Stress and disease likely linked

A new commentary in the Oct. 10 edition of the Journal of the American Medical Association explores whether psychological stress leads to disease and concludes that the link is likely.

10 Oct 2007