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Study finds no significant survival benefit from participating in cancer clinical trials

Participation in cancer clinical trials often suggests improved survival rates, but high-quality studies accounting for biases show no significant survival benefit. Trial benefits may be overstated due to confounding factors.

23 May 2024

Gene cluster expression analysis for personalized lung cancer therapy

About 30% of lung cancer patients are accessible to targeted therapy or immunotherapy based on the current criteria.

23 May 2024

New chemical modification improves effectiveness and safety of ASO therapy for CNS diseases

Diseases that affect the brain and spinal cord can be particularly devastating, and finding new and more effective ways to treat these conditions is an important goal for researchers and clinicians alike.

23 May 2024

Are step counts as effective as time-based exercise in boosting health?

Monitoring physical activity with either step counts or time spent exercising shows similar benefits in reducing cardiovascular disease and all-cause mortality among women in their 60s. Both methods support health guidelines and personal preference.

23 May 2024

Clomiphene and dexamethasone boost fertility in PCOS patients

Combined clomiphene and dexamethasone treatment improves pregnancy and ovulation rates in PCOS patients, with minimal adverse effects. Further research is needed to optimize dosage and duration.

22 May 2024

New study advocates for de-escalating breast cancer surgery in women aged 55 and older

Surgery involving sentinel lymph node biopsy for middle-aged women with estrogen receptor-positive (ER+) breast cancer may do more harm than good, according to a new study led by University of Pittsburgh and UPMC Hillman Cancer Center researchers.

22 May 2024

Dupilumab shows promise in cutting COPD flare-ups and boosting lung function

Dupilumab significantly reduces exacerbations and improves lung function in COPD patients with elevated eosinophil counts, confirming the efficacy of targeting type 2 inflammation.

22 May 2024

Review highlights the rapidly evolving landscape of hepatocellular carcinoma treatment

Hepatocellular carcinoma (HCC), a prevalent form of cancer, profoundly influences the progression and prognosis of the disease through immune response mechanisms.

22 May 2024

Emotional dysregulation identified as core symptom of ADHD

Cambridge scientists have shown that problems regulating emotions – which can manifest as depression, anxiety and explosive outbursts – may be a core symptom of attention deficit hyperactivity disorder (ADHD).

22 May 2024

Biological similarities found between "chemo brain" and brain fog after COVID-19

Brain fog after COVID-19 is biologically similar to cognitive impairment caused by cancer chemotherapy, something doctors often refer to as "chemo brain."

22 May 2024

California pays meth users to get sober

Here in the rugged foothills of California's Sierra Nevada, the streets aren't littered with needles and dealers aren't hustling drugs on the corner.

22 May 2024

Closed Loop Medicine appoints Paul Johnson as Non-Executive Director

Closed Loop Medicine Ltd., a leading TechBio company developing combination prescription drug plus software therapy products that deliver personalized dose optimization, today announced the appointment of Paul Johnson as an Independent Non-Executive Director.

From Closed Loop Medicine 22 May 2024

Study reveals low adoption of recommended smart inhaler therapy for asthma

Only 14.5 percent of adult patients with moderate or severe asthma are prescribed the recommended SMART combination inhaler regimen and over 40 percent of academic pulmonary and allergy clinicians have not adopted this optimal therapy, according to research published at the ATS 2024 International Conference.

21 May 2024

Tailored antibody-drug conjugate offers hope for aggressive breast cancer

Scientists have used breast cancer cells' weakness against themselves by linking a tumour-selective antibody with a cell-killing drug to destroy hard-to-treat tumors.

21 May 2024

Understanding the role of oxidative stress in Alzheimer's disease pathogenesis

The number of people suffering from Alzheimer's disease (AD) is expected to reach 100 million by 2050, but there is still no effective therapy.

21 May 2024

Novel therapy reprograms immune cells, shrinks prostate and bladder cancers in animal study

A novel therapy that reprograms immune cells to promote antitumor activity helped shrink hard-to-treat prostate and bladder cancers in mice, according to research from the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy and Johns Hopkins Drug Discovery.

21 May 2024

Exercise enhances efficacy of antibody therapy in leukemia patients

Bouts of moderate-to-vigorous intensity exercise could improve the efficacy of antibody therapies used to treat chronic lymphocytic leukemia, new research has shown.

21 May 2024

Study offers new insights into how ketamine works

A World Health Organization Essential Medicine, ketamine is widely used at varying doses for sedation, pain control, general anesthesia and as a therapy for treatment-resistant depression.

21 May 2024

Can music therapy improve language development in preterm children by 24 months?

The impact of parent-led, infant-directed singing on language development at 24 months.

21 May 2024

Taurine supplementation shows promise in reducing metabolic syndrome risk factors, study finds

A study in Nutrition & Diabetes meta-analyzed randomized clinical trials and found that taurine supplementation significantly reduces key risk factors for metabolic syndrome, such as high blood pressure, fasting blood glucose, and triglycerides, with no notable adverse effects.

20 May 2024

Therapy News and Research

Study finds no significant survival benefit from participating in cancer clinical trials

Gene cluster expression analysis for personalized lung cancer therapy

New chemical modification improves effectiveness and safety of ASO therapy for CNS diseases

Are step counts as effective as time-based exercise in boosting health?

Clomiphene and dexamethasone boost fertility in PCOS patients

New study advocates for de-escalating breast cancer surgery in women aged 55 and older

Dupilumab shows promise in cutting COPD flare-ups and boosting lung function

Review highlights the rapidly evolving landscape of hepatocellular carcinoma treatment

Emotional dysregulation identified as core symptom of ADHD

Biological similarities found between "chemo brain" and brain fog after COVID-19

California pays meth users to get sober

Closed Loop Medicine appoints Paul Johnson as Non-Executive Director

Study reveals low adoption of recommended smart inhaler therapy for asthma

Tailored antibody-drug conjugate offers hope for aggressive breast cancer

Understanding the role of oxidative stress in Alzheimer's disease pathogenesis

Novel therapy reprograms immune cells, shrinks prostate and bladder cancers in animal study

Exercise enhances efficacy of antibody therapy in leukemia patients

Study offers new insights into how ketamine works

Can music therapy improve language development in preterm children by 24 months?

Taurine supplementation shows promise in reducing metabolic syndrome risk factors, study finds

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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