immunity News and Research

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Male fertility and androgen production may be impacted by COVID-19

An interesting new study has appeared online in the journal Hormones that discusses the effects of COVID-19 on the male and female gonads.

22 Mar 2021

Could nanoparticle vaccines offer broad protection against sarbecoviruses?

To understand the ability of SARS-CoV-2 vaccine-elicited antibodies to neutralize and protect against emerging variants (that are pathogenic) and other sarbecoviruses, a large team of researchers studied immunity by receptor-binding domain nanoparticle vaccines. They showed that a clinical-stage multivalent SARS-CoV-2 receptor-binding domain nanoparticle vaccine (SARS-CoV-2 RBD-NP) protected mice from the SARS-CoV-2-induced disease.

22 Mar 2021

Vaccine passports raise questions of equity, security, and privacy

Vaccine passports raise questions of equity, security, privacy, argues Crispin Maslog. China, where the COVID-19 pandemic began a long year ago, has now become the first country in the world to issue a vaccine passport to promote world economic recovery and facilitate cross-border travel.

22 Mar 2021

Circular RNA vaccine shows neutralizing activity against B.1.351 variant

New preclinical research led by Wensheng Wei from Peking University in China has proposed the development of a circular RNA vaccine. Their findings showed the circular RNA vaccine creates neutralizing antibodies and strong T-cell responses against the receptor-binding domain of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein.

21 Mar 2021

Research suggests SARS-CoV-2 vaccine distribution strategy focusing on where virus spreads more easily

The United States is a few days from reaching President Biden's goal of vaccinating 100 million people 100 days since he took office. While the United States leads the world in both the number of COVID-19 cases at over 29.7 million and deaths reaching past 539,000, it has stepped up as a leader in vaccinating its population.

21 Mar 2021

ChAdOx1 nCoV-19 offers less protection against South African SARS-CoV-2 variant

The results of a double-blind, randomized, multisite placebo-controlled trial that was conducted in South Africa show that Oxford’s ChAdOx1 nCoV-19 (AZD1222) vaccine has no efficacy against the B.1.351 variant in preventing mild-to-moderate coronavirus disease 2019 (COVID-19), and shows reduced neutralization properties of developed antibodies. The findings are published in the New England Journal of Medicine.

21 Mar 2021

Study: 8 out of 10 Spanish health professionals are willing to be vaccinated against COVID-19

Approximately 8 out of every 10 health professionals in Spain are willing to be vaccinated against COVID-19, according to a study led by researchers from the Universitat Oberta de Catalunya.

20 Mar 2021

SARS-CoV-2 spike stimulates hyperinflammation via Toll-like receptor 2

A new study, released on the bioRxiv* preprint server, describes the mechanism of inflammation in severe COVID-19, besides revealing a potential new therapeutic target to modulate the severity of COVID-19.

19 Mar 2021

New variant may not have changed COVID-19 pandemic course in UK, says study

A new study examines the effect of the new "Kent variant" of SARS-CoV-2 on the epidemic course within the UK.

19 Mar 2021

Researchers explore nanotechnology’s potential to deliver synergistic therapeutics for COVID-19

A team of scientists reviewed the nanoencapsulation approaches of synergistic compounds (Lectins, Caffeine, Cocoa, Flavonoids, Quercetin) and the role of nanotechnology in addressing the COVID-19 pandemic.

19 Mar 2021

Researchers investigate the effect of COVID-19 vaccines on residents of long-term care homes

Long-term care homes have been at the epicenter of the COVID-19 pandemic in Canada, with 70 percent of COVID-19 deaths having occurred in long-term care or nursing homes.

19 Mar 2021

N-terminal domain antibodies play a key role in COVID immunity

Scientists are learning that a lesser-studied region on the pandemic coronavirus is recognized by COVID-19 infection-fighting antibodies. These antibodies were identified in blood samples from previously infected patients, and were found to potently prevent the virus from infecting cells.

19 Mar 2021

Mass vaccination needed to protect against future resurgences of COVID-19

The first long-term seroprevalence study of residents in Wuhan, China, has found that 6.9% of people in the city had antibodies against COVID-19 in April 2020, and 82% of these people had an asymptomatic infection.

19 Mar 2021

SARS-CoV-2 vaccination should be carefully targeted towards certain groups, say researchers

Researchers in the UK have provided important insights into the impact that vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – may have on infection rates, disease prevalence and immune escape by the virus.

18 Mar 2021

New study provides comparative analysis of twelve COVID-19 vaccines

A new study by Novateur Ventures provides a comparative analysis of twelve COVID-19 Vaccines that had initiated or announced the Phase III clinical trial stage by early November 2020.

18 Mar 2021

Study highlights the importance of protecting elderly people from COVID-19 reinfection

Most people who have had COVID-19 are protected from catching it again for at least six months, but elderly patients are more prone to reinfection, according to research published in The Lancet.

18 Mar 2021

Study reveals unknown immune defense system that protects the lungs from viral infections

Researchers have uncovered a previously unknown arm of the immune defence system that protects the lung from lethal viral infections.

18 Mar 2021

How resistant is the SARS-CoV-2 Brazilian variant to antibodies?

Researchers based at the University of Oxford, UK, have shown that the P.1 Brazilian variant of SARS-CoV-2 is less resistant to natural or vaccine acquired antibody responses than the B.1.351, South African, variant, despite sharing convergent mutations.

18 Mar 2021

Can vaccine evading SARS-CoV-2 variants be restricted by prioritized vaccine rollout?

A new study discusses the question of how vaccine priority is affected by the possibility of vaccine escape.

18 Mar 2021

Microbiota modulation and re-establishment of eubiosis could help curb COVID-19 complications

In the paper published in the journal Frontiers in Immunology, the researchers noted that since both the respiratory tract and the gastrointestinal mucosa are affected in COVID-19, it is possible that adjunctive therapies that modulate the gut-lung axis.

18 Mar 2021

immunity News and Research

Male fertility and androgen production may be impacted by COVID-19

Could nanoparticle vaccines offer broad protection against sarbecoviruses?

Vaccine passports raise questions of equity, security, and privacy

Circular RNA vaccine shows neutralizing activity against B.1.351 variant

Research suggests SARS-CoV-2 vaccine distribution strategy focusing on where virus spreads more easily

ChAdOx1 nCoV-19 offers less protection against South African SARS-CoV-2 variant

Study: 8 out of 10 Spanish health professionals are willing to be vaccinated against COVID-19

SARS-CoV-2 spike stimulates hyperinflammation via Toll-like receptor 2

New variant may not have changed COVID-19 pandemic course in UK, says study

Researchers explore nanotechnology’s potential to deliver synergistic therapeutics for COVID-19

Researchers investigate the effect of COVID-19 vaccines on residents of long-term care homes

N-terminal domain antibodies play a key role in COVID immunity

Mass vaccination needed to protect against future resurgences of COVID-19

SARS-CoV-2 vaccination should be carefully targeted towards certain groups, say researchers

New study provides comparative analysis of twelve COVID-19 vaccines

Study highlights the importance of protecting elderly people from COVID-19 reinfection

Study reveals unknown immune defense system that protects the lungs from viral infections

How resistant is the SARS-CoV-2 Brazilian variant to antibodies?

Can vaccine evading SARS-CoV-2 variants be restricted by prioritized vaccine rollout?

Microbiota modulation and re-establishment of eubiosis could help curb COVID-19 complications

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