Compound News and Research

RSS

MMV390048 shows potent activity against multiple points in malaria parasite's lifecycle

A recently discovered compound from the aminopyridine class not only has the potential to become part of a single-dose cure for all strains of malaria, but might also be able to block transmission of the parasite from person to person, according to a research collaboration involving the Medicines for Malaria Venture (MMV), based in Switzerland, and the Drug Discovery and Development Centre (H3-D) at the University of Cape Town, South Africa.

29 Aug 2012

Scientists identify genes that underlie growth of primitive leukemia stem cells

University of Rochester Medical Center scientists believe they are the first to identify genes that underlie the growth of primitive leukemia stem cells, and then to use the new genetic signature to identify currently available drugs that selectively target the rogue cells.

29 Aug 2012

Top-line results from Rexahn’s Archexin Phase II study on metastatic pancreatic cancer

Rexahn Pharmaceuticals, Inc., a clinical stage biopharmaceutical company focused on developing multi-indication therapeutics in oncology and CNS, today announced top-line results from a Phase II clinical study of Archexin, its clinical-stage oncology drug candidate.

29 Aug 2012

Elixir Medical’s DESyne BD Novolimus Eluting Coronary Stent System receives CE Mark approval

Elixir Medical Corporation, a developer of product platforms that combine state-of-the-art medical devices with advanced pharmaceuticals, announced that it has received CE Mark approval for its DESyne BD Novolimus Eluting Coronary Stent System for the treatment of coronary artery disease.

29 Aug 2012

$LCZ696 demonstrates beneficial effects in heart failure patients with preserved ejection fraction$

LCZ696 demonstrates beneficial effects in heart failure patients with preserved ejection fraction

The novel angiotensin receptor neprilysin inhibitor, LCZ696, demonstrated beneficial effects in heart failure patients with preserved ejection fraction (HFpEF), according to results of the PARAMOUNT (Prospective compArison of ARNI with ARB on Management Of heart failUre with preserved ejectioN fracTion) trial.

27 Aug 2012

Results from Roche's trastuzumab emtansine Phase III trial on HER2-positive breast cancer

ImmunoGen, Inc., a biotechnology company that develops anticancer products using its Targeted Antibody Payload (TAP) technology and antibody expertise, today announced that Roche has reported that updated results from its EMILIA Phase III trial show that patients treated with trastuzumab emtansine had a significant improvement in OS compared to those randomized to standard-of-care therapy.

27 Aug 2012

PEI adjuvant improves effect of vaccines against flu, HIV and herpes

Oxford University scientists have discovered a compound that greatly boosts the effect of vaccines against viruses like flu, HIV and herpes in mice.

26 Aug 2012

Bristol-Myers Squibb terminates BMS-986094 Phase II development for treatment of hepatitis C

Bristol-Myers Squibb Company announced today that the Company has discontinued development of BMS-986094 (formerly known as INX-189), a nucleotide polymerase (NS5B) inhibitor that was in Phase II development for the treatment of hepatitis C.

24 Aug 2012

NCKU research team identifies Au nanorod complex for cancer therapy

A National Cheng Kung University (NCKU) research team has discovered Near-Infrared Light-Responsive oligonucleotide-gated Au nanoensembles (Au nanorod complex), a potent new anti-cancer complex that is seen as a promising targeted therapy for curing cancer.

24 Aug 2012

Researcher describes structure and function of tuberculosis efflux pump regulator

Edward Yu took note of the facts - nearly 2 million deaths each year, 9 million infected each year, developments of multidrug-resistant, extensively drug-resistant and now totally drug-resistant strains - and decided to shift his research focus to tuberculosis.

23 Aug 2012

Epigallocatechin gallate can shrink cancerous tumours

A compound found in green tea could be a weapon in treatments for tackling cancer, according to newly-published research at the University of Strathclyde in Glasgow, Scotland.

23 Aug 2012

Spicy solution for viral infection

Curcumin, the main compound in the spice turmeric, prevents replication of mosquito-borne Rift Valley Fever virus in infected cells, report researchers.

22 Aug 2012

Methyl-glyoxal could play a major role in abdominal obesity, insulin resistance and type 2 diabetes

Researchers at Mount Sinai School of Medicine have identified a common compound in the modern diet that could play a major role in the development of abdominal obesity, insulin resistance, and type 2 diabetes.

21 Aug 2012

MitoTarget Project and neurodegenerative diseases: an interview with Rebecca Pruss, Ph.D., CSO of Trophos

The MitoTarget Project was a project funded by the European Commission, under their FP7 programme. It was funding for a call published in 2007.

21 Aug 2012

BioDiem and French partner VIVALIS a step forward in developing vaccines for diseases and related cancers

Australian infectious disease therapy and vaccine development company BioDiem Ltd (ASX: BDM) announced today successful results from two programs of work carried out by French partner VIVALIS (NYSE Euronext: VLS), confirming the ability of BioDiem’s Live Attenuated Influenza Virus (LAIV) to grow in VIVALIS’ proprietary EB66® cell line.

20 Aug 2012

Resveratrol might help improve mobility and prevent life-threatening falls among older people

In a stride toward better health in later life, scientists reported today that resveratrol, the so-called "miracle molecule" found in red wine, might help improve mobility and prevent life-threatening falls among older people.

20 Aug 2012

New birth-control strategy for mosquitoes can combat malaria

Using information about the unique mating practices of the male malaria mosquito ― which, unlike any other insect, inserts a plug to seal its sperm inside the female ― scientists are zeroing in on a birth-control drug for Anopheles mosquitoes, deadly carriers of the disease that threatens 3 billion people, has infected more than 215 million and kills 655,000 annually.

20 Aug 2012

Computer simulations shed light on dynamic structure of major target for anti-cancer drugs

Using advanced computer simulations, University of Utah College of Pharmacy researchers have produced moving images of a protein complex that is an important target for anti-cancer drugs.

18 Aug 2012

FibeBiotics aims to prove benefits of polysaccharides in clinical trials

Staying healthy requires constantly stimulating the immune system. Ingesting non-digestible fibres such as polysaccharides is thought to help. Yet companies including such ingredients in their food products cannot claim that they boost the immune system. At least, not until they have been scientifically tested and proven in clinical trials. Only then, would the European Food Safety Agency (EFSA) allow such health claims.

18 Aug 2012

Researchers use small molecule compound to generate reversible birth control in male mice

The development of a male contraceptive pill has long proven to be elusive, but findings from a new study may point scientists in the right direction to making oral birth control for men a reality.

17 Aug 2012

Compound News and Research

MMV390048 shows potent activity against multiple points in malaria parasite's lifecycle

Scientists identify genes that underlie growth of primitive leukemia stem cells

Top-line results from Rexahn’s Archexin Phase II study on metastatic pancreatic cancer

Elixir Medical’s DESyne BD Novolimus Eluting Coronary Stent System receives CE Mark approval

LCZ696 demonstrates beneficial effects in heart failure patients with preserved ejection fraction

Results from Roche's trastuzumab emtansine Phase III trial on HER2-positive breast cancer

PEI adjuvant improves effect of vaccines against flu, HIV and herpes

Bristol-Myers Squibb terminates BMS-986094 Phase II development for treatment of hepatitis C

NCKU research team identifies Au nanorod complex for cancer therapy

Researcher describes structure and function of tuberculosis efflux pump regulator

Epigallocatechin gallate can shrink cancerous tumours

Spicy solution for viral infection

Methyl-glyoxal could play a major role in abdominal obesity, insulin resistance and type 2 diabetes

MitoTarget Project and neurodegenerative diseases: an interview with Rebecca Pruss, Ph.D., CSO of Trophos

BioDiem and French partner VIVALIS a step forward in developing vaccines for diseases and related cancers

Resveratrol might help improve mobility and prevent life-threatening falls among older people

New birth-control strategy for mosquitoes can combat malaria

Computer simulations shed light on dynamic structure of major target for anti-cancer drugs

FibeBiotics aims to prove benefits of polysaccharides in clinical trials

Researchers use small molecule compound to generate reversible birth control in male mice

Advancing therapeutic biopolymer development eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Latest News