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How do people become depressed? An interview with Anna Watters and Professor Lea Williams, University of Sydney

A clinical diagnosis of depression (i.e. major depressive disorder) is currently defined on the basis of reported symptoms.

19 Feb 2014

Omeros doses first patient in second Phase 2 clinical trial of OMS824

Omeros Corporation today announced dosing of the first patient in a second Phase 2 clinical trial of OMS824, the company's phosphodiesterase 10 (PDE10) inhibitor being developed for the treatment of schizophrenia, Huntington's disease (HD) and other cognitive disorders. The Phase 2 trial will evaluate the tolerability, safety, pharmacokinetics and performance on a battery of tests in patients with symptomatic HD.

19 Feb 2014

Exposure to family problems during childhood and early adolescence affects brain development

New research has revealed that exposure to common family problems during childhood and early adolescence affects brain development, which could lead to mental health issues in later life.

19 Feb 2014

Watching video of simple tasks may boost brain's structure, shows study

Watching video of simple tasks before carrying them out may boost the brain's structure, or plasticity, and increase motor skills, according to a study released today that will be presented at the American Academy of Neurology's 66th Annual Meeting in Philadelphia, April 26 to May 3, 2014. Brain plasticity is the brain's ability to flex and adapt, allowing for better learning.

19 Feb 2014

Sleep apnea may contribute to fatigue in people with multiple sclerosis

People with multiple sclerosis (MS) might assume that the fatigue they often feel just comes with the territory of their chronic neurological condition.

17 Feb 2014

Highlights: N.D. hospital and abortion docs; Calif. sugary beverage bill; aging home care workers in Texas

A Democratic candidate who has explicitly defended Obamacare holds a slight lead in a special congressional election in Florida that both parties are eyeing as a test of the political impact of the healthcare law. A poll released Thursday by the Tampa Bay Times shows Democrat Alex Sink leading her Republican opponent, David Jolly, 42% to 35% among people considered likely to vote in the March 11 special election.

17 Feb 2014

Economy of bodily management responsible for widespread use of illegal steroids among MLB players

The widespread use of illegal steroids among Major League Baseball players has been fueled by an "economy of bodily management," the free agent market and exploding television revenues, a UT Arlington assistant professor argues in a newly published research paper.

16 Feb 2014

FAST-MAG clinical trial finds that magnesium does not improve stroke-related disability

In the first study of its kind, a consortium led by UCLA physicians found that giving stroke patients intravenous magnesium within an hour of symptom onset does not improve stroke outcomes, according to research presented today at the American Stroke Association's International Stroke Conference.

14 Feb 2014

Women's blood clot risk remains elevated for at least 12 weeks after delivering a baby, says study

Women's blood clot risk remains elevated for at least 12 weeks after delivering a baby - twice as long as previously recognized, according to a large study presented at the American Stroke Association's International Stroke Conference 2014.

14 Feb 2014

Brain's ability to rebuild itself after stroke holds promise for treating long-term disability in adults

Enhancing the brain's inherent ability to rebuild itself after a stroke with molecular components of stem cells holds enormous promise for treating the leading cause of long-term disability in adults.

14 Feb 2014

Intravenous magnesium fails to improve stroke-related disability

Giving intravenous magnesium to stroke patients soon after the start of symptoms, in an attempt to protect brain cells deprived of oxygen, failed to improve stroke-related disability 3 months later, according to research presented at the American Stroke Association's International Stroke Conference 2014

13 Feb 2014

Researchers validate new method for calculating physical activity, sedentary behavior in obese people

Researchers at the University of South Carolina's Arnold School of Public Health have validated a new method for calculating physical activity, sedentary behavior, and the food energy requirements of Americans. The results suggest that as a nation, we spend more than 15 hours per day sleeping and sitting, and that obese men and women spend less than one minute per day in vigorous activity.

13 Feb 2014

Study disputes effectiveness of mortality as measure of quality of care provided to stroke patients

A new study disputes the effectiveness of mortality as a measure of the quality of care provided by hospitals to stroke patients. The paper - which was simultaneously presented today at the International Stroke Conference in San Diego and published in the journal Stroke - found that use of do-not-resuscitate orders differ widely between hospitals and that this variation can significantly skew a hospital's quality "ranking" based on mortality.

13 Feb 2014

Researchers examine link between non-restorative sleep and widespread pain among older adults

Researchers in the U.K. report that non-restorative sleep is the strongest, independent predictor of widespread pain onset among adults over the age of 50. According to the study published in Arthritis & Rheumatology (formerly Arthritis & Rheumatism), a journal of the American College of Rheumatology (ACR), anxiety, memory impairment, and poor physical health among older adults may also increase the risk of developing widespread pain.

13 Feb 2014

Study to examine effectiveness of using video calls to deliver care for people with Parkinson's disease

People living with Parkinson's disease today often face challenges when seeking care, including disability, distance from medical centers, and distribution of doctors. In fact, 42 percent of those diagnosed with Parkinson's disease, and more living with the condition, do not see a neurologist for their care. Now, a national study will attempt to disrupt the status quo and bring expert Parkinson's care directly into patients' homes using video visit technology.

12 Feb 2014

Adolescents with psychiatric problems more likely to suffer chronic pain

For the first time researchers have studied the kind of physical pain that troubles adolescents with different mental health problems.

12 Feb 2014

Cocaine increases ischemic stroke risk in young adults within 24 hours of use

Cocaine greatly increases ischemic stroke risk in young adults within 24 hours of use, according to research presented at the American Stroke Association's International Stroke Conference 2014.

12 Feb 2014

Ario Pharma begins XEN-0501 Phase IIa study for treatment persistent cough in COPD patients

Ario Pharma Ltd, the Cambridge biopharmaceutical company developing innovative new approaches to treat respiratory disease, announced today that it has commenced a Phase IIa study of its TRPV1 antagonist, XEN-0501, for the treatment and prevention of cough in patients with chronic obstructive pulmonary disease (COPD). Persistent cough in COPD and other respiratory conditions present as a huge unmet medical need, with novel therapies urgently needed to improve the quality of life of patients.

11 Feb 2014

Omeros announces additional positive data from OMS824 Phase 1 program

Omeros Corporation today announced additional positive data from its Phase 1 program for OMS824, the lead compound in Omeros' phosphodiesterase 10 (PDE10) program. This clinical trial evaluated the extent to which OMS824 binds to PDE10, an enzyme expressed in the region of the brain that has been linked to a wide range of diseases that affect cognition. In the latest cohort enrolled in this trial, OMS824 achieved a high of approximately 70‑percent engagement at PDE10 without evidence of extrapyramidal symptoms (EPS).

11 Feb 2014

State highlights: Wis. Bill would limit worker's comp medical costs; Democratic AG in N.C. to appeal abortion ultrasound ruling; Conn. Medicaid primary care docs double since 2011

Wisconsin would put tighter caps on how much doctors and physical therapists could be paid to treat injured patients covered by worker's compensation insurance, under a bill before lawmakers.

11 Feb 2014

Disability News and Research

How do people become depressed? An interview with Anna Watters and Professor Lea Williams, University of Sydney

Omeros doses first patient in second Phase 2 clinical trial of OMS824

Exposure to family problems during childhood and early adolescence affects brain development

Watching video of simple tasks may boost brain's structure, shows study

Sleep apnea may contribute to fatigue in people with multiple sclerosis

Highlights: N.D. hospital and abortion docs; Calif. sugary beverage bill; aging home care workers in Texas

Economy of bodily management responsible for widespread use of illegal steroids among MLB players

FAST-MAG clinical trial finds that magnesium does not improve stroke-related disability

Women's blood clot risk remains elevated for at least 12 weeks after delivering a baby, says study

Brain's ability to rebuild itself after stroke holds promise for treating long-term disability in adults

Intravenous magnesium fails to improve stroke-related disability

Researchers validate new method for calculating physical activity, sedentary behavior in obese people

Study disputes effectiveness of mortality as measure of quality of care provided to stroke patients

Researchers examine link between non-restorative sleep and widespread pain among older adults

Study to examine effectiveness of using video calls to deliver care for people with Parkinson's disease

Adolescents with psychiatric problems more likely to suffer chronic pain

Cocaine increases ischemic stroke risk in young adults within 24 hours of use

Ario Pharma begins XEN-0501 Phase IIa study for treatment persistent cough in COPD patients

Omeros announces additional positive data from OMS824 Phase 1 program

State highlights: Wis. Bill would limit worker's comp medical costs; Democratic AG in N.C. to appeal abortion ultrasound ruling; Conn. Medicaid primary care docs double since 2011

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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