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Scientists map structure of key part of immune system responsible for neutralizing bacteria, viruses

Leicester scientists have mapped the "bouquet-like" structure of a key part of the body's immune system responsible for neutralising bacteria and viruses.

5 Nov 2013

S14G-humanin: New effective treatment for Alzheimer's disease

Humanin is a potential therapeutic agent for Alzheimer's disease, and its derivative, S14G-humanin, is 1 000-fold stronger in its neuroprotective effect against Alzheimer's disease-relevant insults. Al-though effective, the detailed molecular mechanism through which S14G-humanin exerts its effects remains unclear.

31 Oct 2013

Scientists unravel the major cause of protein citrullination in rheumatoid arthritis

Experiments by scientists at Johns Hopkins and in Boston have unraveled two biological mechanisms as the major cause of protein citrullination in rheumatoid arthritis. Protein citrullination is suspected of sparking the immune system and driving the cascade of events leading to the disease.

31 Oct 2013

Meclizine drug has the potential to treat certain infectious diseases and cancer

Meclizine, an over-the-counter drug used for decades to treat nausea and motion sickness, has the potential for new uses to treat certain infectious diseases and some forms of cancer, according to Dr. Vishal M. Gohil, Texas A&M AgriLife Research biochemist.

31 Oct 2013

MiMedx Group reports record revenue in third quarter 2013

MiMedx Group, Inc., an integrated developer, manufacturer and marketer of patent protected regenerative biomaterials and bioimplants processed from human amniotic membrane, announced today its results for the quarter ended September 30, 2013.

30 Oct 2013

Researchers develop new substance that quickly and effectively kills multi-resistant bacteria

In Europe alone, more than 25,000 people die each year from infections caused by multi-resistant bacteria. Researchers from University of Copenhagen have now developed and characterized a substance that quickly and effectively kills the virulent bacteria. The substance employs a multifunctional mechanism that reduces the risk of antibiotic resistance. The findings have recently been published in the scientific journal Chemistry & Biology.

30 Oct 2013

Sanovas receives patent for Multi-Balloon Catheter for Extravasated Drug Delivery

Sanovas Inc., (www.sanovas.com) a life science technology company focused on developing and commercializing next generation micro-invasive diagnostics, devices and drug delivery technologies, announced today that the United States Patent and Trademark Office issued patent # 8,540,667 for the company's Multi-Balloon Catheter for Extravasated Drug Delivery.

29 Oct 2013

Research findings open up possibility for developing potent anti-clotting drugs

Researchers at the University of Illinois at Chicago have discovered a molecular switch that causes small, beneficial clots that stop bleeding to enlarge further during wound healing. By blocking this switch in lab mice, the researchers prevented small clots from growing -- a process that can pose a danger in humans -- while preserving their ability to staunch bleeding

29 Oct 2013

Study reveals that specific protein may assist breast cancer cells in metastasizing

A new study by University of Kentucky Markey Cancer Center researchers Min Chen and Kathleen O'Connor shows that a specific protein may assist breast cancer cells in metastasizing.

29 Oct 2013

Smartphone-enabled otoscope provides clear images of ear tympanic membrane

A new, smartphone-enabled otoscope provides clear, transmittable images of the ear drum, or tympanic membrane, which someday may allow for ear infection diagnosis without a visit to the doctor's office, according to an abstract presented Monday, Oct. 28, at the American Academy of Pediatrics National Conference and Exhibition in Orlando.

28 Oct 2013

Plant Sterols prove to be better cholesterol in Alzheimer`s disease

"Plant sterols are present in various combinations in nuts, seeds and plant oils. As plant sterols are the equivalents of animal cholesterol, they can in principal influence metabolic processes, where cholesterol is involved," explained Marcus Grimm, Head of the Experimental Neurology Laboratory at Saarland University. "Because they also lower cholesterol levels, they are extensively used in the food industry and as dietary supplements."

25 Oct 2013

"One-two punch" disables tumors' defenses

An aggressive form of breast cancer known as "triple negative" is very difficult to treat: Chemotherapy can shrink such tumors for a while, but in many patients they grow back and gain resistance to the original drugs.

25 Oct 2013

Study shows plant sterols appear to prevent onset of Alzheimer's disease

It's no secret that many of the phytochemicals in fruit and vegetables have a positive effect on our health. For instance, plant sterols (also known as phytosterols) help to lower cholesterol levels. According to a new study by researchers at Saarland University, they also appear to prevent the onset of Alzheimer's disease.

24 Oct 2013

BUSM researchers capture images of channels that direct proteins to right place in cell membranes

Similar to passengers on an urban transit system, every protein made in the cell has a specific destination and function. Channels in cell membranes help direct these proteins to their appropriate target. Researchers at Boston University School of Medicine and their colleagues have now captured images of these channels as they open to allow proteins to pass through a membrane, while the proteins are being made.

24 Oct 2013

Researchers use nanopores to smuggle DNA or proteins across membranes

A living cell is built with barriers to keep things out - and researchers are constantly trying to find ways to smuggle molecules in.‬ ‪Professor Giovanni Maglia (Biochemistry, Molecular and Structural Biology, KU Leuven) and his team have engineered a biological nanopore that acts as a selective revolving door through a cell's lipid membrane. The nanopore could potentially be used in gene therapy and targeted drug delivery.‬‬‬‬‬‬‬

24 Oct 2013

Fatty acid entry into cells happens by diffusion

The current global epidemic of obesity-linked diabetes and its associated consequences -cardiovascular, neurological and renal diseases - is a growing public health problem for which therapeutic options are limited.

23 Oct 2013

GenSpera presents final data from G-202 Phase I clinical trial at EORTC-NCI-AACR Symposium

GenSpera, Inc. (OTCBB:GNSZ) announced that Devalingam Mahalingam, MD, PhD, principal investigator of the G-202 Phase II trial in hepatocellular carcinoma, presented final data from the G-202 Phase I clinical trial yesterday at the EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Boston, MA.

23 Oct 2013

Discovery sheds light on how forces outside of cells get translated into internal signals

Johns Hopkins researchers used suction to learn that individual "molecular muscles" within cells respond to different types of force, a finding that may explain how cells "feel" the environment and appropriately adapt their shapes and activities.

21 Oct 2013

Clarified role of signal-relay proteins may help explain spread of cancer

Cell biologists at The Johns Hopkins University have teased apart two integral components of the machinery that causes cells to move. Their discovery shows that cellular projections, which act as hands to help a cell "crawl," are apparently always initiated by a network of message-relaying proteins inside the cell.

21 Oct 2013

GenSpera to present G-202 Phase I trial in hepatocellular carcinoma at EORTC-NCI-AACR Symposium

GenSpera, Inc. (OTCBB:GNSZ) announced that Devalingam Mahalingam, MD, PhD, principal investigator of the G-202 Phase II trial in hepatocellular carcinoma, will present data from the G-202 Phase I clinical trial at the EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Boston, MA on Monday, October 21st.

18 Oct 2013

Membrane News and Research

Scientists map structure of key part of immune system responsible for neutralizing bacteria, viruses

S14G-humanin: New effective treatment for Alzheimer's disease

Scientists unravel the major cause of protein citrullination in rheumatoid arthritis

Meclizine drug has the potential to treat certain infectious diseases and cancer

MiMedx Group reports record revenue in third quarter 2013

Researchers develop new substance that quickly and effectively kills multi-resistant bacteria

Sanovas receives patent for Multi-Balloon Catheter for Extravasated Drug Delivery

Research findings open up possibility for developing potent anti-clotting drugs

Study reveals that specific protein may assist breast cancer cells in metastasizing

Smartphone-enabled otoscope provides clear images of ear tympanic membrane

Plant Sterols prove to be better cholesterol in Alzheimer`s disease

"One-two punch" disables tumors' defenses

Study shows plant sterols appear to prevent onset of Alzheimer's disease

BUSM researchers capture images of channels that direct proteins to right place in cell membranes

Researchers use nanopores to smuggle DNA or proteins across membranes

Fatty acid entry into cells happens by diffusion

GenSpera presents final data from G-202 Phase I clinical trial at EORTC-NCI-AACR Symposium

Discovery sheds light on how forces outside of cells get translated into internal signals

Clarified role of signal-relay proteins may help explain spread of cancer

GenSpera to present G-202 Phase I trial in hepatocellular carcinoma at EORTC-NCI-AACR Symposium

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