Protein C News and Research

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Senolytic therapy in mild Alzheimer’s disease shows safety in phase I trial

Researchers conducted the phase 1 trial of orally-administered senolytic therapy comprising quercetin (Q) and dasatinib (D) for symptomatic and early-stage Alzheimer's disease (AD) patients.

8 Sep 2023

Theabrownin from dark tea may have the potential to treat insulin resistance

The effects of theabrownin (TB) from dark tea treatment on insulin resistance (IR).

8 Sep 2023

Does caffeine interact with genetic risk factors for Parkinson's disease in Asians?

The interaction of caffeine with Leucine rich repeat kinase 2 (LRRK2) genetic risk variants in Asians.

8 Sep 2023

Self-adjuvanting RNA vaccines boost immune response 10x more than existing vaccines

RNA vaccines against Covid-19 have proven effective at reducing the severity of disease. However, a team of researchers at MIT is working on making them even better.

8 Sep 2023

Phase I trial of senolytic therapy shows promise in Alzheimer's disease

Alzheimer's disease is the most common cause of dementia that affects more than 6.5 million Americans, according to the Alzheimer's Association.

8 Sep 2023

Unraveling the relationship between obesity-related metabolic dysfunction and endotrophin

With obesity rates projected to continue rising globally, there is an urgent need to understand the intricate mechanisms that contribute to metabolic diseases such as diabetes.

8 Sep 2023

A subset of CD8+ T cells can play a protective role against Alzheimer’s disease pathogenesis

Scientists at St. Jude Children’s Research Hospital found that a subset of CD8+ T cells in the brain lessens the activation of microglia and limits disease pathology in a model of Alzheimer’s disease.

8 Sep 2023

New device can warn about early risks of tooth decay from gingivitis and periodontitis

Engineers at the University of Cincinnati have developed a new device that can warn consumers about early risks of tooth decay from diseases such as gingivitis and periodontitis.

8 Sep 2023

Blood clots may be a cause of long-term cognitive problems after COVID-19

High levels of two proteins at the time of COVID-19 have been found in patients who later experienced cognitive problems, including 'brain fog', giving a major clue as to one cause of their symptoms: blood clots.

7 Sep 2023

Can brown fat really keep you slim? New study digs into the science of diet-induced thermogenesis

The research paper delves into the role of brown adipose tissue and its protein, UCP1, in diet-induced thermogenesis, questioning whether it could be a key to fighting obesity. Despite some evidence suggesting that brown fat activity could influence weight, the study calls for more research to determine the causality between reduced brown adipose tissue activity and obesity.

7 Sep 2023

Could your gut microbiome shape your teenage years? New study dives into the lifelong health impact

Research explores how the gut microbiota impacts critical areas of adolescent development, including mental health, metabolism, and skeletal growth. It suggests that understanding these interactions could lead to microbiome-based treatments for optimal growth and maturation.

7 Sep 2023

Is your body clock the secret to peak athletic performance?

Review comprehensively explores how the circadian rhythm impacts sports performance, hormonal regulation, and immune system function in athletes. The study emphasizes the optimal times of day for athletic performance and underlines the role of circadian rhythm in hormonal balance and immune responses.

7 Sep 2023

Chronic inflammation's influence on TP53 mutations in leukemia evolution explored in new study

Researchers performed a multi-omics evaluation of HSPCs obtained from individuals with myeloproliferative neoplasms transforming to TP53-related secondary forms of acute myeloid leukemia.

7 Sep 2023

Specialized astrocyte subpopulation discovery sheds light on brain health and treatment avenues

In a recent study published in Nature, researchers investigated whether glutamatergic gliotransmission was mediated by specialized astrocytes in the central nervous system.

7 Sep 2023

Novel method using DNA nanoballs could revolutionize pathogen detection

Researchers at Karolinska Institute have developed a novel method using DNA Nanoballs to detect pathogens, aiming to simplify nucleic acid testing and revolutionize pathogen detection.

7 Sep 2023

Eating for health: how dietary interventions impact pre-diabetic oral and gut microbiome, metabolites and cytokines

Researchers evaluated the impact of two diets on the intestinal and oral microbiota, cytokines, and metabolites of 200 pre-diabetic individuals.

7 Sep 2023

Exploring the benefits of walnut flour in gluten-free bread

Researchers evaluated the physicochemical, sensory, and spectroscopic characteristics of walnut flour (WF) as an ingredient for producing low-carbohydrate bread.

7 Sep 2023

BA.2.86 Omicron variant: Is our immunity under siege?

A new preprint posted to the bioRxiv server discusses whether this variant shows neutralization escape.

7 Sep 2023

RIT researchers use CRISPR to develop new treatment for degenerative disc disease

Rochester Institute of Technology researchers are improving non-invasive treatment options for degenerative disc disease, an ailment that impacts 3 million adults yearly in the U.S., according to the Mayo Clinic.

6 Sep 2023

Cracking the obesity code: The protein leverage hypothesis

The research paper presents an integrative approach to understanding obesity, focusing on the protein leverage hypothesis (PLH) to examine how protein intake affects energy imbalance. It combines insights from nutritional ecology, ecological sciences, and nutritional geometry, suggesting that protein deficiency and amino acid imbalances could drive increased food intake and contribute to obesity.

6 Sep 2023

Protein C News and Research

Senolytic therapy in mild Alzheimer’s disease shows safety in phase I trial

Theabrownin from dark tea may have the potential to treat insulin resistance

Does caffeine interact with genetic risk factors for Parkinson's disease in Asians?

Self-adjuvanting RNA vaccines boost immune response 10x more than existing vaccines

Phase I trial of senolytic therapy shows promise in Alzheimer's disease

Unraveling the relationship between obesity-related metabolic dysfunction and endotrophin

A subset of CD8+ T cells can play a protective role against Alzheimer’s disease pathogenesis

New device can warn about early risks of tooth decay from gingivitis and periodontitis

Blood clots may be a cause of long-term cognitive problems after COVID-19

Can brown fat really keep you slim? New study digs into the science of diet-induced thermogenesis

Could your gut microbiome shape your teenage years? New study dives into the lifelong health impact

Is your body clock the secret to peak athletic performance?

Chronic inflammation's influence on TP53 mutations in leukemia evolution explored in new study

Specialized astrocyte subpopulation discovery sheds light on brain health and treatment avenues

Novel method using DNA nanoballs could revolutionize pathogen detection

Eating for health: how dietary interventions impact pre-diabetic oral and gut microbiome, metabolites and cytokines

Exploring the benefits of walnut flour in gluten-free bread

BA.2.86 Omicron variant: Is our immunity under siege?

RIT researchers use CRISPR to develop new treatment for degenerative disc disease

Cracking the obesity code: The protein leverage hypothesis

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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