Epidemiology News and Research

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'Human knockouts': Genetics in families reveals basic biology and possible therapeutics for disorders

More than 1,800 individuals carrying loss-of-function mutations in both copies of their genes, so-called "human knockouts," are described in the first major study to be published in Nature this week by an international collaboration led by the Perelman School of Medicine at the University of Pennsylvania and colleagues.

12 Apr 2017

Frequent hot flashes may be linked to increased heart disease risk

Hot flashes, one of the most common symptoms of menopause, have already been shown to interfere with a woman's overall quality of life.

12 Apr 2017

Researchers identify three novel genetic mutations linked to Fuchs dystrophy

Researchers discovered three novel genetic mutations associated with Fuchs endothelial corneal dystrophy, the most common corneal disorder requiring transplantation.

12 Apr 2017

Duke researchers link specific differences in brain structure to multiple forms of mental disorder

A Duke University study is the first to link specific differences in brain structure to what is common across many types of mental illness.

11 Apr 2017

Antimicrobial protein reduces creamy white lesions linked to oral thrush in mouse models

An antimicrobial protein caused a dramatic reduction in the creamy white lesions associated with oral thrush in a preclinical study, report microbiologists with McGovern Medical School at The University of Texas Health Science Center at Houston.

11 Apr 2017

Cholera incidence in Africa increases during El Niño, study reveals

Cholera cases in East Africa increase by roughly 50,000 during El Niño, the cyclical weather occurrence that profoundly changes global weather patterns, new Johns Hopkins Bloomberg School of Public Health research suggests.

11 Apr 2017

Study aims to characterize relationships of incarcerated African-Americans and STI/HIV risk

HIV incidence among African-American men is nearly eight times that of white men, and twice that of Latino men. Incarceration, which disproportionately affects African-American men, is thought to be a factor in this wide disparity.

11 Apr 2017

UC Davis professor awarded Mellon Foundation Fellowship to study environmental hazards

Liza Grandia, associate professor of Native American studies at the University of California, Davis, has received a $270,000 Mellon Foundation New Directions Fellowship.

7 Apr 2017

IBD patients with longer duration of disease have higher risk of developing NAFLD

Research led by a Houston Methodist gastroenterologist shows that patients who have inflammatory bowel disease (IBD) for more than two decades have a higher risk of developing nonalcoholic fatty liver disease (NAFLD).

5 Apr 2017

Number of HIV-positive cancer patients in the U.S. projected to decrease through 2030

As the population of people living with HIV in the United States ages, the burden of cancer for these patients is expected to shift away from cancers linked to AIDS and toward malignancies that affect the general population, according to a new study led by a University of North Carolina at Chapel Hill researcher.

5 Apr 2017

Genetic screening and counseling likely to benefit childhood cancer survivors, study suggests

Twelve percent of childhood cancer survivors carry germline mutations that put them or their children at increased risk of developing cancer, according to a landmark study presented today at the annual meeting of the American Association for Cancer Research.

4 Apr 2017

Electrical stimulation on spinal cord and physical therapy help patient to move paralyzed legs

Mayo Clinic researchers used electrical stimulation on the spinal cord and intense physical therapy to help a man intentionally move his paralyzed legs, stand and make steplike motions for the first time in three years.

4 Apr 2017

Extreme short and long telomeres linked to increased cancer risk

The length of the telomere "caps" of DNA that protect the tips of chromosomes may predict cancer risk and be a potential target for future therapeutics, University of Pittsburgh Cancer Institute scientists will report today at the AACR Annual Meeting in Washington, D.C.

3 Apr 2017

Study reports rising thyroid cancer incidence among Hispanics, African Americans and young people

In the United States, thyroid cancer incidence is rising among young people as well as Hispanics and African Americans, a new study reports. Results of this research will be presented in a poster Monday, April 3, at ENDO 2017, the annual scientific meeting of the Endocrine Society, in Orlando, Fla.

3 Apr 2017

Flavors in e-cigarettes linked to increasing use among youth and young adults

Flavored e-cigarettes and e-cigarette marketing could be increasing e-cigarette use among youth and young adults, according to researchers from the Michael & Susan Dell Center for Healthy Living at The University of Texas Health Science Center at Houston School of Public Health in Austin.

2 Apr 2017

Fighting colorectal cancer

Colorectal cancer is a combined term to describe the malignant tumors that occur in the large intestine; the colon being the upper part of the large intestine and the rectum being the lowest part of the large intestine.

31 Mar 2017

Study: Major databases provide varying estimates of racial gaps in IBR after mastectomy

Three major national databases include varying estimates of racial gaps in the use of immediate breast reconstruction (IBR) after mastectomy for breast cancer, reports a study in the March issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

30 Mar 2017

Gum disease and tooth loss may be linked to increased risk of death in postmenopausal women

Gum disease and tooth loss may be associated with a higher risk of death in postmenopausal women but not increased cardiovascular disease risk, according to new research in Journal of the American Heart Association, the open access journal of the American Heart Association/American Stroke Association.

29 Mar 2017

Traumatic events during adolescence can raise women’s risk of depression during menopause

Although depression is common during a woman's transition to menopause, understanding who is at-risk of experiencing major depressive disorder (MDD) during this period of hormonal fluctuation were previously unknown.

29 Mar 2017

High blood pressure not related to elevated mortality risk for older adults with weak grip strength

A study of nearly 7,500 Americans age 65 or older suggests that elevated blood pressure is not related to high mortality risk among people in that age group with weak grip strength.

28 Mar 2017

Epidemiology News and Research

'Human knockouts': Genetics in families reveals basic biology and possible therapeutics for disorders

Frequent hot flashes may be linked to increased heart disease risk

Researchers identify three novel genetic mutations linked to Fuchs dystrophy

Duke researchers link specific differences in brain structure to multiple forms of mental disorder

Antimicrobial protein reduces creamy white lesions linked to oral thrush in mouse models

Cholera incidence in Africa increases during El Niño, study reveals

Study aims to characterize relationships of incarcerated African-Americans and STI/HIV risk

UC Davis professor awarded Mellon Foundation Fellowship to study environmental hazards

IBD patients with longer duration of disease have higher risk of developing NAFLD

Number of HIV-positive cancer patients in the U.S. projected to decrease through 2030

Genetic screening and counseling likely to benefit childhood cancer survivors, study suggests

Electrical stimulation on spinal cord and physical therapy help patient to move paralyzed legs

Extreme short and long telomeres linked to increased cancer risk

Study reports rising thyroid cancer incidence among Hispanics, African Americans and young people

Flavors in e-cigarettes linked to increasing use among youth and young adults

Fighting colorectal cancer

Study: Major databases provide varying estimates of racial gaps in IBR after mastectomy

Gum disease and tooth loss may be linked to increased risk of death in postmenopausal women

Traumatic events during adolescence can raise women’s risk of depression during menopause

High blood pressure not related to elevated mortality risk for older adults with weak grip strength

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