Protein C News and Research

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Pitt neuroscientists create first non-human primate model of hereditary Alzheimer's in marmosets

To reimagine existing preclinical trials for Alzheimer's disease, University of Pittsburgh School of Medicine neuroscientists created the first non-human primate model of hereditary Alzheimer's in marmoset monkeys, outlining their approach in Alzheimer's & Dementia: Translational Research & Clinical Interventions.

6 Sep 2023

Review identifies future research directions for the study of a SARS-CoV-2 reservoir in PASC

Researchers reviewed the evidence for SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC).

6 Sep 2023

Researchers characterize new SARS-CoV-2 BA.2.86 variant neutralization by monoclonal antibodies

Researchers used a SARS-CoV-2 spike protein-pseudotyped viral model to characterize BA.2.86 variant neutralization by monoclonal antibodies.

6 Sep 2023

Does dahlia flower extract have anti-diabetic properties?

The effects of an extract of yellow petals of Dahlia pinnata as a novel treatment of type 2 diabetes (T2D).

6 Sep 2023

Monovalent vaccine outperforms bivalent in fighting new Omicron variants

New U.S. study finds mRNA-1273.815, a monovalent vaccine targeting the Omicron XBB.1.5 variant, generates higher neutralizing antibody titers compared to its bivalent counterpart. The study supports updating to an XBB.1.5-based monovalent vaccine for the 2023-24 campaign to combat emerging variants.

5 Sep 2023

Researchers receive $2.5 million award to develop a tailored treatment for glioblastoma

A multidisciplinary team of investigators from the UCLA Jonsson Comprehensive Cancer Center was awarded a $2.5 million Translational Team Science Award from the Department of Defense to develop a tailored treatment for glioblastoma, a deadly brain tumor with limited treatment options.

5 Sep 2023

Novavax's updated XBB.1.5 vaccine shows promising cross-neutralizing antibodies against new COVID-19 variants

The study reveals that Novavax's updated XBB.1.5 vaccine effectively induces cross-neutralizing antibodies against multiple Omicron XBB sub-variants in both mice and non-human primates.

5 Sep 2023

Could medicinal plants be the key to reversing cognitive decline?

Researchers explore available evidence that medicinal plants may help improve cognitive function by reducing brain inflammation.

5 Sep 2023

Can SARS-CoV-2 infect poultry?

New research in the Virology Journal suggests that chickens could become intermediate hosts for newly emerged SARS-CoV-2 variants, posing a potential threat to public health. The study identifies AXL and ACE2 receptors in chickens as likely binding sites for the virus, highlighting the need for further research and preventive measures.

5 Sep 2023

Diet sodas trick your saliva: Study reveals how sweetened drinks impact oral enzymes and insulin levels

The study investigates the effects of sweetened beverages on salivary insulin, aspartame, and alpha-amylase levels in healthy young adults. It found that diet soft drinks led to higher salivary aspartame and insulin levels compared to sweetened water, raising questions about artificial sweeteners' impact on metabolic processes.

5 Sep 2023

How is next-generation protein sequencing democratizing protein sequencing?

In this interview, NewsMedical speaks with Jeff Hawkins, CEO of Quantum-Si, about the challenges of conventional proteomic methods, as well as how next-generation protein sequencing is democratizing protein sequencing.

From Quantum-SI 5 Sep 2023

Targeting the ORAI1 calcium channel could provide new approach to treating oral cancer

An essential protein that acts as a gatekeeper for calcium entering cells promotes the growth of oral cancer and generates pain, according to a new study published in Science Signaling led by researchers at NYU College of Dentistry.

5 Sep 2023

SARS-CoV-2 spike protein could be speeding up Alzheimer's and other brain diseases, says new study

Swedish researchers find that SARS-CoV-2's spike protein amyloids can accelerate the formation of harmful protein aggregates related to neurodegenerative diseases like Creutzfeldt-Jakob and Alzheimer's. The study suggests a potential link between COVID-19 and increased cases of these brain disorders.

5 Sep 2023

How SARS-CoV-2 hijacks Fragile X proteins to fuel infection: New clues in COVID-19 and genetic disorders

Study explores the interaction between SARS-CoV-2's non-structural protein 3 (NSP3) and proteins related to Fragile X mental retardation (FMRPs), shedding light on COVID-19 pathophysiology. The research suggests that the virus exploits these host cell proteins for effective infection and possibly interferes with antiviral defense mechanisms, offering new insights into the genetic basis of Fragile X syndrome.

5 Sep 2023

Evaluating the risks of fish allergy from thermostable allergens in canned fish

The safety of consuming canned fish for fish-allergic patients.

4 Sep 2023

Study reports highly pathogenic avian influenza A infection in pet dogs and cat on a rural poultry farm in Italy

Researchers presented serological evidence of highly pathogenic avian influenza (HPAI) H5N1 virus infection in a pet cat and five dogs on a rural poultry farm in Italy.

4 Sep 2023

Study explores the role of sex on mRNA and protein levels and its genetic regulation in brain

Researchers investigated the impact of biological sex on protein levels and its genomic control by analyzing 1,277 proteomes of the brain.

4 Sep 2023

Study explores the biology of post-COVID-19 cognitive deficits

Researchers explored the biology of cognitive deficits following acute COVID-19.

4 Sep 2023

New cancer therapy shows promise in mouse models, slows or reverses tumor growth

A new cancer therapy developed by Purdue University researchers attacks tumors by tricking cancer cells into absorbing a snippet of RNA that naturally blocks cell division.

4 Sep 2023

New biomarker could help identify people at risk for vascular dementia

Dementia is a group of brain diseases that share similar symptoms, such as memory, language, orientation, and behavioral issues. Vascular dementia generally develops in the elderly, affecting between 1% and 4% of people over the age of 65, according to Alzheimer's Switzerland.

4 Sep 2023

Protein C News and Research

Pitt neuroscientists create first non-human primate model of hereditary Alzheimer's in marmosets

Review identifies future research directions for the study of a SARS-CoV-2 reservoir in PASC

Researchers characterize new SARS-CoV-2 BA.2.86 variant neutralization by monoclonal antibodies

Does dahlia flower extract have anti-diabetic properties?

Monovalent vaccine outperforms bivalent in fighting new Omicron variants

Researchers receive $2.5 million award to develop a tailored treatment for glioblastoma

Novavax's updated XBB.1.5 vaccine shows promising cross-neutralizing antibodies against new COVID-19 variants

Could medicinal plants be the key to reversing cognitive decline?

Can SARS-CoV-2 infect poultry?

Diet sodas trick your saliva: Study reveals how sweetened drinks impact oral enzymes and insulin levels

How is next-generation protein sequencing democratizing protein sequencing?

Targeting the ORAI1 calcium channel could provide new approach to treating oral cancer

SARS-CoV-2 spike protein could be speeding up Alzheimer's and other brain diseases, says new study

How SARS-CoV-2 hijacks Fragile X proteins to fuel infection: New clues in COVID-19 and genetic disorders

Evaluating the risks of fish allergy from thermostable allergens in canned fish

Study reports highly pathogenic avian influenza A infection in pet dogs and cat on a rural poultry farm in Italy

Study explores the role of sex on mRNA and protein levels and its genetic regulation in brain

Study explores the biology of post-COVID-19 cognitive deficits

New cancer therapy shows promise in mouse models, slows or reverses tumor growth

New biomarker could help identify people at risk for vascular dementia

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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