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OrthoTrophix commences TPX-100 Phase 2 clinical study in knee osteoarthritis patients

OrthoTrophix, Inc., a privately held biopharmaceutical company, announced today that the Company started a Phase 2 clinical study of its cartilage repair therapeutic agent, TPX-100, with knee osteoarthritis patients in the U.S. The Company also announced that it had successfully closed the second and last tranche of its Series A preferred stock financing.

20 Feb 2014

Sedentary behavior may be a risk factor for disability once we reach our 60s

People in their 60s who spend too much time sitting down may be increasing their risk of becoming disabled, a study shows.

20 Feb 2014

Head movement during fMRI may bias sampling toward subjects with lower cognitive ability

Kessler Foundation researchers have shown that discarding data from subjects with multiple sclerosis (MS) who exhibit head movement during functional magnetic resonance imaging (fMRI) may bias sampling away from subjects with lower cognitive ability.

20 Feb 2014

Medications to lower blood pressure after stroke does not reduce likelihood of death

A major study has found that giving stroke patients medications to lower their blood pressure during the first 48 hours after a stroke does not reduce the likelihood of death or major disability.

20 Feb 2014

New information on pathogenesis of feeding and swallowing difficulties in kids with autism

Collaborative research out of the George Washington University (GW) reveals new information on the pathogenesis of feeding and swallowing difficulties often found in children with neurodevelopmental disorders, including autism and intellectual disability.

20 Feb 2014

Too much sedentary time linked to major disability after 60

If you're 60 and older, every additional hour a day you spend sitting is linked to doubling the risk of being disabled -- regardless of how much moderate exercise you get, reports a new Northwestern Medicine- study.

19 Feb 2014

How do people become depressed? An interview with Anna Watters and Professor Lea Williams, University of Sydney

A clinical diagnosis of depression (i.e. major depressive disorder) is currently defined on the basis of reported symptoms.

19 Feb 2014

Omeros doses first patient in second Phase 2 clinical trial of OMS824

Omeros Corporation today announced dosing of the first patient in a second Phase 2 clinical trial of OMS824, the company's phosphodiesterase 10 (PDE10) inhibitor being developed for the treatment of schizophrenia, Huntington's disease (HD) and other cognitive disorders. The Phase 2 trial will evaluate the tolerability, safety, pharmacokinetics and performance on a battery of tests in patients with symptomatic HD.

19 Feb 2014

Exposure to family problems during childhood and early adolescence affects brain development

New research has revealed that exposure to common family problems during childhood and early adolescence affects brain development, which could lead to mental health issues in later life.

19 Feb 2014

Watching video of simple tasks may boost brain's structure, shows study

Watching video of simple tasks before carrying them out may boost the brain's structure, or plasticity, and increase motor skills, according to a study released today that will be presented at the American Academy of Neurology's 66th Annual Meeting in Philadelphia, April 26 to May 3, 2014. Brain plasticity is the brain's ability to flex and adapt, allowing for better learning.

19 Feb 2014

Sleep apnea may contribute to fatigue in people with multiple sclerosis

People with multiple sclerosis (MS) might assume that the fatigue they often feel just comes with the territory of their chronic neurological condition.

17 Feb 2014

Highlights: N.D. hospital and abortion docs; Calif. sugary beverage bill; aging home care workers in Texas

A Democratic candidate who has explicitly defended Obamacare holds a slight lead in a special congressional election in Florida that both parties are eyeing as a test of the political impact of the healthcare law. A poll released Thursday by the Tampa Bay Times shows Democrat Alex Sink leading her Republican opponent, David Jolly, 42% to 35% among people considered likely to vote in the March 11 special election.

17 Feb 2014

Economy of bodily management responsible for widespread use of illegal steroids among MLB players

The widespread use of illegal steroids among Major League Baseball players has been fueled by an "economy of bodily management," the free agent market and exploding television revenues, a UT Arlington assistant professor argues in a newly published research paper.

16 Feb 2014

FAST-MAG clinical trial finds that magnesium does not improve stroke-related disability

In the first study of its kind, a consortium led by UCLA physicians found that giving stroke patients intravenous magnesium within an hour of symptom onset does not improve stroke outcomes, according to research presented today at the American Stroke Association's International Stroke Conference.

14 Feb 2014

Women's blood clot risk remains elevated for at least 12 weeks after delivering a baby, says study

Women's blood clot risk remains elevated for at least 12 weeks after delivering a baby - twice as long as previously recognized, according to a large study presented at the American Stroke Association's International Stroke Conference 2014.

14 Feb 2014

Brain's ability to rebuild itself after stroke holds promise for treating long-term disability in adults

Enhancing the brain's inherent ability to rebuild itself after a stroke with molecular components of stem cells holds enormous promise for treating the leading cause of long-term disability in adults.

14 Feb 2014

Intravenous magnesium fails to improve stroke-related disability

Giving intravenous magnesium to stroke patients soon after the start of symptoms, in an attempt to protect brain cells deprived of oxygen, failed to improve stroke-related disability 3 months later, according to research presented at the American Stroke Association's International Stroke Conference 2014

13 Feb 2014

Researchers validate new method for calculating physical activity, sedentary behavior in obese people

Researchers at the University of South Carolina's Arnold School of Public Health have validated a new method for calculating physical activity, sedentary behavior, and the food energy requirements of Americans. The results suggest that as a nation, we spend more than 15 hours per day sleeping and sitting, and that obese men and women spend less than one minute per day in vigorous activity.

13 Feb 2014

Study disputes effectiveness of mortality as measure of quality of care provided to stroke patients

A new study disputes the effectiveness of mortality as a measure of the quality of care provided by hospitals to stroke patients. The paper - which was simultaneously presented today at the International Stroke Conference in San Diego and published in the journal Stroke - found that use of do-not-resuscitate orders differ widely between hospitals and that this variation can significantly skew a hospital's quality "ranking" based on mortality.

13 Feb 2014

Researchers examine link between non-restorative sleep and widespread pain among older adults

Researchers in the U.K. report that non-restorative sleep is the strongest, independent predictor of widespread pain onset among adults over the age of 50. According to the study published in Arthritis & Rheumatology (formerly Arthritis & Rheumatism), a journal of the American College of Rheumatology (ACR), anxiety, memory impairment, and poor physical health among older adults may also increase the risk of developing widespread pain.

13 Feb 2014

Disability News and Research

OrthoTrophix commences TPX-100 Phase 2 clinical study in knee osteoarthritis patients

Sedentary behavior may be a risk factor for disability once we reach our 60s

Head movement during fMRI may bias sampling toward subjects with lower cognitive ability

Medications to lower blood pressure after stroke does not reduce likelihood of death

New information on pathogenesis of feeding and swallowing difficulties in kids with autism

Too much sedentary time linked to major disability after 60

How do people become depressed? An interview with Anna Watters and Professor Lea Williams, University of Sydney

Omeros doses first patient in second Phase 2 clinical trial of OMS824

Exposure to family problems during childhood and early adolescence affects brain development

Watching video of simple tasks may boost brain's structure, shows study

Sleep apnea may contribute to fatigue in people with multiple sclerosis

Highlights: N.D. hospital and abortion docs; Calif. sugary beverage bill; aging home care workers in Texas

Economy of bodily management responsible for widespread use of illegal steroids among MLB players

FAST-MAG clinical trial finds that magnesium does not improve stroke-related disability

Women's blood clot risk remains elevated for at least 12 weeks after delivering a baby, says study

Brain's ability to rebuild itself after stroke holds promise for treating long-term disability in adults

Intravenous magnesium fails to improve stroke-related disability

Researchers validate new method for calculating physical activity, sedentary behavior in obese people

Study disputes effectiveness of mortality as measure of quality of care provided to stroke patients

Researchers examine link between non-restorative sleep and widespread pain among older adults

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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